Kinzler, Kenneth W.
The University of Sydney · The University of Melbourne · Walter and Eliza Hall Institute of Medical Research · Peter MacCallum Cancer Centre · Eastern Health · Sidney Kimmel Cancer Center · Western Health · Sidney Kimmel Comprehensive Cancer Center
69 papers on CoChatORCID 0000-0001-5591-1176
Most cited papers
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Intratumoral injection of Clostridium novyi -NT spores induces antitumor responses
Roberts, N. J., Zhang, L., Janku, F., Collins, A., Bai, R.-Y., Staedtke, V., Rusk, A. W., Tung, D., Miller, M., Roix, J., et al. (2014) · Science Translational Medicine
Bacterial Cancer TherapyClostridium difficile and Clostridium perfringens research
Cited by 400
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Disruption of HAUSP gene stabilizes p53.
Cummins, J. M., Rago, C., Kohli, M., Kinzler, K. W., Lengauer, C., & Vogelstein, B. (2004) · Nature
Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways
Cited by 379
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SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer
Blackford, A., Serrano, O. K., Wolfgang, C. L., Parmigiani, G., Jones, S., Zhang, X., Parsons, D. W., Lin, J. C.-H., Leary, R. J., Eshleman, J. R., et al. (2009) · Clinical Cancer Research
Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics
Cited by 371
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Targeting a neoantigen derived from a common TP53 mutation
Hsiue, E. H.-C., Wright, K. M., Douglass, J., Hwang, M. S., Mog, B. J., Pearlman, A. H., Paul, S., DiNapoli, S. R., Konig, M. F., Wang, Q., et al. (2021) · Science
Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers
Cited by 367
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Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer
Roberts, N. J., Norris, A. L., Petersen, G. M., Bondy, M. L., Brand, R., Gallinger, S., Kurtz, R. C., Olson, S. H., Rustgi, A. K., Schwartz, A. G., et al. (2016) · Cancer Discovery
Pancreatic and Hepatic Oncology ResearchGenetic factors in colorectal cancer
Cited by 361
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Sensitive digital quantification of DNA methylation in clinical samples
Li, M., Chen, W.-D., Papadopoulos, N., Goodman, S. N., Bjerregaard, N. C., Laurberg, S., Levin, B., Juhl, H., Arber, N., Moinova, H., et al. (2009) · Nature Biotechnology
Epigenetics and DNA MethylationCancer Genomics and Diagnostics
Cited by 341
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Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers.
Kinde, I., Bettegowda, C., Wang, Y., Wu, J., Agrawal, N., Shih, I.-M., Kurman, R., Dao, F., Levine, D. A., Giuntoli, R., et al. (2013) · Science Translational Medicine
Cancer Genomics and DiagnosticsCervical Cancer and HPV Research
Cited by 327
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Next-Generation Stool DNA Test Accurately Detects Colorectal Cancer and Large Adenomas
Ahlquist, D. A., Zou, H., Domanico, M., Mahoney, D. W., Yab, T. C., Taylor, W. R., Butz, M. L., Thibodeau, S. N., Rabeneck, L., Paszat, L. F., et al. (2012) · Gastroenterology
Colorectal Cancer Screening and DetectionGenetic factors in colorectal cancer
Cited by 315
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Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer
Hao, Y., Samuels, Y., Li, Q., Krokowski, D., Guan, B.-J., Wang, C., Jin, Z., Dong, B., Cao, B., Feng, X., et al. (2016) · Nature Communications
Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer
Cited by 290
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Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome
Staedtke, V., Bai, R.-Y., Kim, K., Darvas, M., Davila, M. L., Riggins, G. J., Rothman, P. B., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., et al. (2018) · Nature
Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses
Cited by 277
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BEAMing up for detection and quantification of rare sequence variants
Li, M., Diehl, F., Dressman, D., Vogelstein, B., & Kinzler, K. W. (2006) · Nature Methods
Advanced biosensing and bioanalysis techniquesMolecular Biology Techniques and Applications
Cited by 261
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TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine
Kinde, I., Munari, E., Faraj, S. F., Hruban, R. H., Schoenberg, M., Bivalacqua, T., Allaf, M., Springer, S., Wang, Y., Diaz, L. A., et al. (2013) · Cancer Research
Bladder and Urothelial Cancer TreatmentsUrinary and Genital Oncology Studies
Cited by 253
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Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing
Hoang, M. L., Kinde, I., Tomasetti, C., McMahon, K. W., Rosenquist, T. A., Grollman, A. P., Kinzler, K. W., Vogelstein, B., & Papadopoulos, N. (2016) · Proceedings of the National Academy of Sciences
Cancer Genomics and DiagnosticsGenomics and Phylogenetic Studies
Cited by 224
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A multimodality test to guide the management of patients with a pancreatic cyst
Springer, S., Masica, D. L., Dal Molin, M., Douville, C., Thoburn, C. J., Afsari, B., Li, L., Cohen, J. D., Thompson, E., Allen, P. J., et al. (2019) · Science Translational Medicine
Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment
Cited by 217
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Characterization of MAD2B and Other Mitotic Spindle Checkpoint Genes
Cahill, D. P., da Costa, L. T., Carson-Walter, E. B., Kinzler, K. W., Vogelstein, B., & Lengauer, C. (1999) · Genomics
Microtubule and mitosis dynamicsCancer-related Molecular Pathways
Cited by 212
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X-Linked Inhibitor of Apoptosis Protein (XIAP) Is a Nonredundant Modulator of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)- Mediated Apoptosis in Human Cancer Cells
Cummins, J. M., Kohli, M., Rago, C., Kinzler, K. W., Vogelstein, B., & Bunz, F. (2004) · Cancer Research
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 200
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Utility of CT Radiomics Features in Differentiation of Pancreatic Ductal Adenocarcinoma From Normal Pancreatic Tissue.
Chu, L. C., Park, S., Kawamoto, S., Fouladi, D. F., Shayesteh, S., Zinreich, E. S., Graves, J. S., Horton, K. M., Hruban, R. H., Yuille, A. L., et al. (2019) · American Journal of Roentgenology
Radiomics and Machine Learning in Medical ImagingPancreatic and Hepatic Oncology Research
Cited by 193
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Bispecific antibodies targeting mutant RAS neoantigens
Douglass, J., Hsiue, E. H.-C., Mog, B. J., Hwang, M. S., DiNapoli, S. R., Pearlman, A. H., Miller, M. S., Wright, K. M., Azurmendi, P. A., Wang, Q., et al. (2021) · Science Immunology
Monoclonal and Polyclonal Antibodies ResearchCancer Immunotherapy and Biomarkers
Cited by 171
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Precancerous neoplastic cells can move through the pancreatic ductal system
Makohon-Moore, A. P., Matsukuma, K., Zhang, M., Reiter, J. G., Gerold, J. M., Jiao, Y., Sikkema, L., Attiyeh, M. A., Yachida, S., Sandone, C., et al. (2018) · Nature
Cancer Genomics and DiagnosticsPancreatic and Hepatic Oncology Research
Cited by 120
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Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis
Dal Molin, M., Zhang, M., de Wilde, R. F., Ottenhof, N. A., Rezaee, N., Wolfgang, C. L., Blackford, A., Vogelstein, B., Kinzler, K. W., Papadopoulos, N., et al. (2015) · Clinical Cancer Research
Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics
Cited by 101
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Classification of pancreatic cystic neoplasms using radiomic feature analysis is equivalent to an experienced academic radiologist: A step toward computer-augmented diagnostics for radiologists
Chu, L. C., Park, S., Soleimani, S., Fouladi, D. F., Shayesteh, S., He, J., Javed, A. A., Wolfgang, C. L., Vogelstein, B., Kinzler, K. W., et al. (2022) · Abdominal Radiology
Radiomics and Machine Learning in Medical ImagingPancreatic and Hepatic Oncology Research
Cited by 39
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