Cupples, L. Adrienne

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Berndt, S. I., Gustafsson, S., Mägi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., et al. (2013) · Nature Genetics

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 646

Homocysteine as a Predictive Factor for Hip Fracture in Older Persons

McLean, R. R., Jacques, P. F., Selhub, J., Tucker, K. L., Samelson, E. J., Broe, K. E., Hannan, M. T., Cupples, L. A., & Kiel, D. P. (2004) · New England Journal of Medicine

Bone health and osteoporosis researchFolate and B Vitamins Research

Cited by 589

Disclosure of APOE Genotype for Risk of Alzheimer's Disease

Green, R. C., Roberts, J. S., Cupples, L. A., Relkin, N. R., Whitehouse, P. J., Brown, T., Eckert, S. L., Butson, M., Sadovnick, A. D., Quaid, K. A., et al. (2009) · New England Journal of Medicine

Dementia and Cognitive Impairment ResearchEthics in Clinical Research

Cited by 554

Depression as a Risk Factor for Alzheimer Disease: The MIRAGE Study

Green, R. C., Cupples, L. A., Kurz, A., Auerbach, S., Go, R., Sadovnick, D., Duara, R., Kukull, W. A., Chui, H., Edeki, T., et al. (2003) · Archives of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 551

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

Zanoni, P., Khetarpal, S. A., Larach, D. B., Hancock-Cerutti, W. F., Millar, J. S., Cuchel, M., DerOhannessian, S., Kontush, A., Surendran, P., Saleheen, D., et al. (2016) · Science

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 545

Effect of Dietary Protein on Bone Loss in Elderly Men and Women: The Framingham Osteoporosis Study

Hannan, M. T., Tucker, K. L., Dawson-Hughes, B., Cupples, L. A., Felson, D. T., & Kiel, D. P. (2000) · Journal of Bone and Mineral Research

Bone health and osteoporosis researchNutrition and Health in Aging

Cited by 536

Recovery of trait heritability from whole genome sequence data

Wainschtein, P., Jain, D., Zheng, Z., TOPMed Anthropometry Working Group, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Cupples, L. A., Shadyab, A. H., McKnight, B., Shoemaker, B. M., Mitchell, B. D., et al. (2019) · Nature Genetics

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 515

Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study

Demissie, S., Levy, D., Benjamin, E. J., Cupples, L. A., Gardner, J. P., Herbert, A., Kimura, M., Larson, M. G., Meigs, J. B., Keaney, J. F., et al. (2006) · Aging Cell

Telomeres, Telomerase, and SenescenceCardiovascular Health and Disease Prevention

Cited by 508

Head injury and the risk of AD in the MIRAGE study

Guo, Z., Cupples, L. A., Kurz, A., Auerbach, S. H., Volicer, L., Chui, H., Green, R. C., Sadovnick, A. D., Duara, R., DeCarli, C., et al. (2000) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 506

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

Desikan, R. S., Fan, C. C., Wang, Y., Schork, A. J., Cabral, H. J., Cupples, L. A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., et al. (2017) · PLoS Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 395

Parental history is an independent risk factor for coronary artery disease: The Framingham Study

Myers, R. H., Kiely, D. K., Cupples, L. A., & Kannel, W. B. (1990) · American Heart Journal

Cardiovascular Health and Risk FactorsGenetic Associations and Epidemiology

Cited by 394

NIDDM and Blood Pressure as Risk Factors for Poor Cognitive Performance: The Framingham Study

Elias, P. K., Elias, M. F., D'Agostino, R. B., Cupples, L. A., Wilson, P. W., Silbershatz, H., & Wolf, P. A. (1997) · Diabetes Care

Dementia and Cognitive Impairment ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 368

Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis

Chasman, D. I., Paré, G., Mora, S., Hopewell, J. C., Peloso, G., Clarke, R., Cupples, L. A., Hamsten, A., Kathiresan, S., Mälarstig, A., et al. (2009) · PLoS Genetics

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 337

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Kilpeläinen, T. O., Zillikens, M. C., Stančákova, A., Finucane, F. M., Ried, J. S., Langenberg, C., Zhang, W., Beckmann, J. S., Luan, J., Vandenput, L., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 335

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old?

Lautenschlager, N. T., Cupples, L. A., Rao, V. S., Auerbach, S. A., Becker, R., Burke, J., Chui, H., Duara, R., Foley, E. J., Glatt, S. L., et al. (1996) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 298

High-density lipoprotein subpopulation profile and coronary heart disease prevalence in male participants of the Framingham Offspring Study.

Asztalos, B. F., Cupples, L. A., Demissie, S., Horvath, K. V., Cox, C. E., Batista, M. C., & Schaefer, E. J. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 298

Value of High-Density Lipoprotein (HDL) Subpopulations in Predicting Recurrent Cardiovascular Events in the Veterans Affairs HDL Intervention Trial

Asztalos, B. F., Collins, D., Cupples, L. A., Demissie, S., Horvath, K. V., Bloomfield, H. E., Robins, S. J., & Schaefer, E. J. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 268

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

Bis, J. C., Jian, X., Kunkle, B. W., Chen, Y., Hamilton-Nelson, K. L., Bush, W. S., Salerno, W. J., Lancour, D., Ma, Y., Renton, A. E., et al. (2020) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 248

Association of Low-Density Lipoprotein Cholesterol–Related Genetic Variants With Aortic Valve Calcium and Incident Aortic Stenosis

Smith, J. G., Luk, K., Schulz, C.-A., Engert, J. C., Do, R., Hindy, G., Rukh, G., Dufresne, L., Almgren, P., Owens, D. S., et al. (2014) · JAMA

Cardiac Valve Diseases and TreatmentsLipoproteins and Cardiovascular Health

Cited by 238

Association of clonal hematopoiesis with chronic obstructive pulmonary disease

Miller, P. G., Qiao, D., Rojas-Quintero, J., Honigberg, M. C., Sperling, A. S., Gibson, C. J., Bick, A. G., Niroula, A., McConkey, M. E., Sandoval, B., et al. (2022) · Blood

Chronic Obstructive Pulmonary Disease (COPD) ResearchAcute Myeloid Leukemia Research

Cited by 235

Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

Tanaka, T., Ngwa, J. S., van Rooij, F. J., Zillikens, M. C., Wojczynski, M. K., Frazier-Wood, A. C., Houston, D. K., Kanoni, S., Lemaitre, R. N., Luan, J., et al. (2013) · The American Journal of Clinical Nutrition

Nutrition, Genetics, and DiseaseGenetic Associations and Epidemiology

Cited by 226

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

the CARDIoGRAM Consortium, Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyCardiovascular Health and Disease Prevention

Cited by 212

A Genetic Risk Score Is Associated With Incident Cardiovascular Disease and Coronary Artery Calcium: The Framingham Heart Study

Thanassoulis, G., Peloso, G. M., Pencina, M. J., Hoffmann, U., Fox, C. S., Cupples, L. A., Levy, D., D'Agostino, R. B., Hwang, S.-J., & O'Donnell, C. J. (2012) · Circulation: Cardiovascular Genetics

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 211