Eisch, Amelia J.

Neurobiology of Depression

Nestler, E. J., Barrot, M., DiLeone, R. J., Eisch, A. J., Gold, S. J., & Monteggia, L. M. (2002) · Neuron

Treatment of Major DepressionStress Responses and Cortisol

Cited by 3,217

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

Malberg, J. E., Eisch, A. J., Nestler, E. J., & Duman, R. S. (2000) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 3,111

Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions

Krishnan, V., Han, M.-H., Graham, D. L., Berton, O., Renthal, W., Russo, S. J., LaPlant, Q., Graham, A., Lutter, M., Lagace, D. C., et al. (2007) · Cell

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 2,307

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

LaPlant, Q., Vialou, V., Covington, H. E., Dumitriu, D., Feng, J., Warren, B. L., Maze, I., Dietz, D. M., Watts, E. L., Iñiguez, S. D., et al. (2010) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorEpigenetics and DNA Methylation

Cited by 612

Opiates inhibit neurogenesis in the adult rat hippocampus

Eisch, A. J., Barrot, M., Schad, C. A., Self, D. W., & Nestler, E. J. (2000) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsNeuropeptides and Animal Physiology

Cited by 599

Depression and Hippocampal Neurogenesis: A Road to Remission?

Eisch, A. J., & Petrik, D. (2012) · Science

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 516

CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli

Barrot, M., Olivier, J. D. A., Perrotti, L. I., DiLeone, R. J., Berton, O., Eisch, A. J., Impey, S., Storm, D. R., Neve, R. L., Yin, J. C., et al. (2002) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 508

Dynamic Contribution of Nestin-Expressing Stem Cells to Adult Neurogenesis

Lagace, D. C., Whitman, M. C., Noonan, M. A., Ables, J. L., DeCarolis, N. A., Arguello, A. A., Donovan, M. H., Fischer, S. J., Farnbauch, L. A., Beech, R. D., et al. (2007) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 502

Neurod1 is essential for the survival and maturation of adult-born neurons

Gao, Z., Ure, K., Ables, J. L., Lagace, D. C., Nave, K.-A., Goebbels, S., Eisch, A. J., & Hsieh, J. (2009) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 473

Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline

Cho, K.-O., Lybrand, Z. R., Ito, N., Brulet, R., Tafacory, F., Zhang, L., Good, L., Ure, K., Kernie, S. G., Birnbaum, S. G., et al. (2015) · Nature Communications

Epilepsy research and treatmentNeurogenesis and neuroplasticity mechanisms

Cited by 451

Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression

Eisch, A. J., Bolaños, C. A., de Wit, J., Simonak, R. D., Pudiak, C. M., Barrot, M., Verhaagen, J., & Nestler, E. J. (2003) · Biological Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 420

Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal

Georgescu, D., Zachariou, V., Barrot, M., Mieda, M., Willie, J. T., Eisch, A. J., Yanagisawa, M., Nestler, E. J., & DiLeone, R. J. (2003) · The Journal of Neuroscience

Neuropeptides and Animal PhysiologySleep and Wakefulness Research

Cited by 373

Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance

Lagace, D. C., Donovan, M. H., DeCarolis, N. A., Farnbauch, L. A., Malhotra, S., Berton, O., Nestler, E. J., Krishnan, V., & Eisch, A. J. (2010) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 314

Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells

Ables, J. L., DeCarolis, N. A., Johnson, M. A., Rivera, P. D., Gao, Z., Cooper, D. C., Radtke, F., Hsieh, J., & Eisch, A. J. (2010) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 292

IκB Kinase Regulates Social Defeat Stress-Induced Synaptic and Behavioral Plasticity

Christoffel, D. J., Golden, S. A., Dumitriu, D., Robison, A. J., Janssen, W. G., Ahn, H. F., Krishnan, V., Reyes, C. M., Han, M.-H., Ables, J. L., et al. (2011) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 267

The neurogenesis hypothesis of affective and anxiety disorders: Are we mistaking the scaffolding for the building?

Petrik, D., Lagace, D. C., & Eisch, A. J. (2012) · Neuropharmacology

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 241

AKT Signaling within the Ventral Tegmental Area Regulates Cellular and Behavioral Responses to Stressful Stimuli

Krishnan, V., Han, M.-H., Mazei-Robison, M., Iñiguez, S. D., Ables, J. L., Vialou, V., Berton, O., Ghose, S., Covington, H. E., Wiley, M. D., et al. (2008) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 176

Kctd13 deletion reduces synaptic transmission via increased RhoA

Escamilla, C. O., Filonova, I., Walker, A. K., Xuan, Z. X., Holehonnur, R., Espinosa, F., Liu, S., Thyme, S. B., López-García, I. A., Mendoza, D. B., et al. (2017) · Nature

Genetics and Neurodevelopmental DisordersGenomic variations and chromosomal abnormalities

Cited by 165

The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

Walker, A. K., Rivera, P. D., Wang, Q., Chuang, J.-C., Tran, S., Osborne-Lawrence, S., Estill, S. J., Starwalt, R., Huntington, P., Morlock, L., et al. (2015) · Molecular Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 161

Galactic cosmic ray simulation at the NASA Space Radiation Laboratory

Norbury, J. W., Schimmerling, W., Slaba, T. C., Azzam, E. I., Badavi, F. F., Baiocco, G., Benton, E., Bindi, V., Blakely, E. A., Blattnig, S. R., et al. (2016) · Life Sciences in Space Research

Radiation Therapy and DosimetryEffects of Radiation Exposure

Cited by 155

Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: Unraveling the genome to understand the mind

Hsieh, J., & Eisch, A. J. (2010) · Neurobiology of Disease

Neurogenesis and neuroplasticity mechanismsEpigenetics and DNA Methylation

Cited by 144

Chronic morphine induces premature mitosis of proliferating cells in the adult mouse subgranular zone

Mandyam, C. D., Norris, R. D., & Eisch, A. J. (2004) · Journal of Neuroscience Research

Neurogenesis and neuroplasticity mechanismsNeuropeptides and Animal Physiology

Cited by 116

Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment

Celen, C., Chuang, J.-C., Luo, X., Nijem, N., Walker, A. K., Chen, F., Zhang, S., Chung, A. S., Nguyen, L. H., Nassour, I., et al. (2017) · eLife

Genetics and Neurodevelopmental DisordersChromatin Remodeling and Cancer

Cited by 113

Cell-autonomous inactivation of the reelin pathway impairs adult neurogenesis in the hippocampus

Teixeira, C. M., Kron, M. M., Masachs, N., Zhang, H., Lagace, D. C., Martinez, A., Reillo, I., Duan, X., Bosch, C., Pujadas, L., et al. (2012) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 97