Seeley, Randy J.

Leptin Receptor Long-form Splice-variant Protein Expression in Neuron Cell Bodies of the Brain and Co-localization with Neuropeptide Y mRNA in the Arcuate Nucleus

Baskin, D. G., Schwartz, M. W., Seeley, R. J., Woods, S. C., Porte, D., Breininger, J. F., Jonak, Z., Schaefer, J., Krouse, M., Burghardt, C., et al. (1999) · Journal of Histochemistry & Cytochemistry

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

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Obesity and gut flora

Bajzer, M., & Seeley, R. J. (2006) · Nature

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

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Obesity, diabetes and the central nervous system

Porte Jr., D., Seeley, R. J., Woods, S. C., Baskin, D. G., Figlewicz, D. P., & Schwartz, M. W. (1998) · Diabetologia

Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic Diseases

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Fibroblast Growth Factor-19 Action in the Brain Reduces Food Intake and Body Weight and Improves Glucose Tolerance in Male Rats

Ryan, K. K., Kohli, R., Gutierrez-Aguilar, R., Gaitonde, S. G., Woods, S. C., & Seeley, R. J. (2013) · Endocrinology

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

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The Integrative Role of CNS Fuel-Sensing Mechanisms in Energy Balance and Glucose Regulation

Sandoval, D., Cota, D., & Seeley, R. J. (2008) · Annual Review of Physiology

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

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Liraglutide modulates appetite and body weight through glucagon-like peptide 1 receptor-expressing glutamatergic neurons

Adams, J. M., Pei, H., Sandoval, D. A., Seeley, R. J., Chang, R. B., Liberles, S. D., & Olson, D. P. (2018) · Diabetes

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

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Violet-light suppression of thermogenesis by opsin 5 hypothalamic neurons

Zhang, K. X., D’Souza, S., Upton, B. A., Kernodle, S., Vemaraju, S., Nayak, G., Gaitonde, K. D., Holt, A. L., Linne, C. D., Smith, A. N., et al. (2020) · Nature

Adipose Tissue and MetabolismRegulation of Appetite and Obesity

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Synaptic plasticity in neuronal circuits regulating energy balance

Zeltser, L. M., Seeley, R. J., & Tschöp, M. H. (2012) · Nature Neuroscience

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

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Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation

Wong, C. K., Yusta, B., Koehler, J. A., Baggio, L. L., McLean, B. A., Matthews, D., Seeley, R. J., & Drucker, D. J. (2022) · Cell Metabolism

Diabetes Treatment and ManagementGut microbiota and health

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The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice

Burmeister, M. A., Ayala, J. E., Smouse, H., Landivar-Rocha, A., Brown, J. D., Drucker, D. J., Stoffers, D. A., Sandoval, D. A., Seeley, R. J., & Ayala, J. E. (2017) · Diabetes

Regulation of Appetite and ObesityDiabetes Treatment and Management

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Dietary sugars, not lipids, drive hypothalamic inflammation

Gao, Y., Bielohuby, M., Fleming, T., Grabner, G. F., Foppen, E., Bernhard, W., Guzmán-Ruiz, M., Layritz, C., Legutko, B., Zinser, E., et al. (2017) · Molecular Metabolism

Neuroinflammation and Neurodegeneration MechanismsRegulation of Appetite and Obesity

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Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding

Cheng, W., Gonzalez, I., Pan, W., Tsang, A. H., Adams, J., Ndoka, E., Gordian, D., Khoury, B., Roelofs, K., Evers, S. S., et al. (2020) · Cell Metabolism

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

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Low plasma leptin levels contribute to diabetic hyperphagia in rats.

Sindelar, D. K., Havel, P. J., Seeley, R. J., Wilkinson, C. W., Woods, S. C., & Schwartz, M. W. (1999) · Diabetes

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

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The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice

Baggio, L. L., Ussher, J. R., McLean, B. A., Cao, X., Kabir, M. G., Mulvihill, E. E., Mighiu, A. S., Zhang, H., Ludwig, A., Seeley, R. J., et al. (2017) · Molecular Metabolism

Diabetes Treatment and ManagementHeart Rate Variability and Autonomic Control

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The gut microbiota regulates hypothalamic inflammation and leptin sensitivity in Western diet-fed mice via a GLP-1R-dependent mechanism

Heiss, C. N., Mannerås-Holm, L., Lee, Y. S., Serrano-Lobo, J., Håkansson Gladh, A., Seeley, R. J., Drucker, D. J., Bäckhed, F., & Olofsson, L. E. (2021) · Cell Reports

Regulation of Appetite and ObesityGut microbiota and health

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Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action

Varin, E. M., Mulvihill, E. E., Baggio, L. L., Koehler, J. A., Cao, X., Seeley, R. J., & Drucker, D. J. (2019) · Cell Reports

Regulation of Appetite and ObesityDiabetes Treatment and Management

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Loss of Cytokine-STAT5 Signaling in the CNS and Pituitary Gland Alters Energy Balance and Leads to Obesity

Lee, J.-Y., Muenzberg, H., Gavrilova, O., Reed, J. A., Berryman, D., Villanueva, E. C., Louis, G. W., Leinninger, G. M., Bertuzzi, S., Seeley, R. J., et al. (2008) · PLoS ONE

Regulation of Appetite and ObesityCytokine Signaling Pathways and Interactions

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Sexually different actions of leptin in proopiomelanocortin neurons to regulate glucose homeostasis

Shi, H., Strader, A. D., Sorrell, J. E., Chambers, J. B., Woods, S. C., & Seeley, R. J. (2008) · American Journal of Physiology-Endocrinology and Metabolism

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

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Differential importance of endothelial and hematopoietic cell GLP-1Rs for cardiometabolic versus hepatic actions of semaglutide

McLean, B. A., Wong, C. K., Kaur, K. D., Seeley, R. J., & Drucker, D. J. (2021) · JCI Insight

Diabetes Treatment and ManagementAtherosclerosis and Cardiovascular Diseases

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Gastric bypass surgery attenuates ethanol consumption in ethanol-preferring rats

Davis, J. F., Schurdak, J. D., Magrisso, I. J., Mul, J. D., Grayson, B. E., Pfluger, P. T., Tschöp, M. H., Seeley, R. J., & Benoit, S. C. (2012) · Biological Psychiatry

Bariatric Surgery and OutcomesRegulation of Appetite and Obesity

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Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism

Huang, Z., Liu, L., Zhang, J., Conde, K., Phansalkar, J., Li, Z., Yao, L., Xu, Z., Wang, W., Zhou, J., et al. (2022) · Science Advances

Regulation of Appetite and ObesityPancreatic function and diabetes

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Glucagon-like peptide-1 receptor agonist treatment does not reduce abuse-related effects of opioid drugs

Bornebusch, A. B., Fink-Jensen, A., Wörtwein, G., Seeley, R. J., & Thomsen, M. (2019) · eneuro

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

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Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models

Rupp, A. C., Tomlinson, A. J., Affinati, A. H., Yacawych, W. T., Duensing, A. M., True, C., Lindsley, S. R., Kirigiti, M. A., MacKenzie, A., Polex-Wolf, J., et al. (2023) · Journal of Clinical Investigation

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

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Biologic responses to weight loss and weight regain: report from an American Diabetes Association research symposium.

Leibel, R. L., Seeley, R. J., Darsow, T., Berg, E. G., Smith, S. R., & Ratner, R. (2015) · Diabetes

Obesity, Physical Activity, DietBariatric Surgery and Outcomes

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