Mechoulam, Raphael

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

Devane, W. A., Hanuš, L., Breuer, A., Pertwee, R. G., Stevenson, L. A., Griffin, G., Gibson, D., Mandelbaum, A., Etinger, A., & Mechoulam, R. (1992) · Science

Cannabis and Cannabinoid ResearchFatty Acid Research and Health

Cited by 5,633

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

Mechoulam, R., Ben-Shabat, S., Hanus, L., Ligumsky, M., Kaminski, N. E., Schatz, A. R., Gopher, A., Almog, S., Martin, B. R., Compton, D. R., et al. (1995) · Biochemical Pharmacology

Cannabis and Cannabinoid ResearchFatty Acid Research and Health

Cited by 2,913

The endocannabinoid system and the brain.

Mechoulam, R., & Parker, L. A. (2013) · Annual Review of Psychology

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 1,090

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

Malfait, A. M., Gallily, R., Sumariwalla, P. F., Malik, A. S., Andreakos, E., Mechoulam, R., & Feldmann, M. (2000) · Proceedings of the National Academy of Sciences

Cannabis and Cannabinoid ResearchNatural Compounds in Disease Treatment

Cited by 669

Cannabidiol—recent advances

Mechoulam, R., Peters, M., Murillo‐Rodriguez, E., & Hanuš, L. O. (2007) · Chemistry & Biodiversity

Cannabis and Cannabinoid ResearchMedicinal Plant Extracts Effects

Cited by 515

Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease

Lastres-Becker, I., Molina-Holgado, F., Ramos, J. A., Mechoulam, R., & Fernández-Ruiz, J. (2005) · Neurobiology of Disease

Cannabis and Cannabinoid ResearchParkinson's Disease Mechanisms and Treatments

Cited by 407

Early phytocannabinoid chemistry to endocannabinoids and beyond

Mechoulam, R., Hanuš, L. O., Pertwee, R., & Howlett, A. C. (2014) · Nature Reviews Neuroscience

Cannabis and Cannabinoid ResearchForensic Toxicology and Drug Analysis

Cited by 393

Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties

García-Arencibia, M., González, S., de Lago, E., Ramos, J. A., Mechoulam, R., & Fernández-Ruiz, J. (2007) · Brain Research

Cannabis and Cannabinoid ResearchParkinson's Disease Mechanisms and Treatments

Cited by 320

Cannabidiol, a non‐psychotropic component of cannabis, attenuates vomiting and nausea‐like behaviour via indirect agonism of 5‐HT1A somatodendritic autoreceptors in the dorsal raphe nucleus

Rock, E., Bolognini, D., Limebeer, C., Cascio, M., Anavi‐Goffer, S., Fletcher, P., Mechoulam, R., Pertwee, R., & Parker, L. (2012) · British Journal of Pharmacology

Cannabis and Cannabinoid ResearchNausea and vomiting management

Cited by 255

Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test

Linares, I. M., Zuardi, A. W., Pereira, L. C., Queiroz, R. H., Mechoulam, R., Guimarães, F. S., & Crippa, J. A. (2019) · Brazilian Journal of Psychiatry

Cannabis and Cannabinoid ResearchMedicinal Plant Extracts Effects

Cited by 241

Cannabinoid CB2receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease

Sagredo, O., González, S., Aroyo, I., Pazos, M. R., Benito, C., Lastres‐Becker, I., Romero, J. P., Tolón, R. M., Mechoulam, R., Brouillet, E., et al. (2009) · Glia

Cannabis and Cannabinoid ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 201

Real life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy

Bar-Lev Schleider, L., Mechoulam, R., Saban, N., Meiri, G., & Novack, V. (2019) · Scientific Reports

Cannabis and Cannabinoid ResearchAutism Spectrum Disorder Research

Cited by 186

Beyond THC and Endocannabinoids

Pacher, P., Kogan, N. M., & Mechoulam, R. (2020) · Annual Review of Pharmacology and Toxicology

Cannabis and Cannabinoid ResearchFatty Acid Research and Health

Cited by 175

Effect of low doses of ?9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats

Parker, L. A., Burton, P., Sorge, R. E., Yakiwchuk, C., & Mechoulam, R. (2004) · Psychopharmacology

Cannabis and Cannabinoid ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 171

Cannabidiol reduced the striatal atrophy caused 3‐nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1and adenosine A2Areceptors

Sagredo, O., Ramos, J. A., Decio, A., Mechoulam, R., & Fernández‐Ruiz, J. (2007) · European Journal of Neuroscience

Cannabis and Cannabinoid ResearchParkinson's Disease Mechanisms and Treatments

Cited by 147

A novel synthetic, nonpsychoactive cannabinoid acid (HU‐320) with antiinflammatory properties in murine collagen‐induced arthritis

Sumariwalla, P. F., Gallily, R., Tchilibon, S., Fride, E., Mechoulam, R., & Feldmann, M. (2004) · Arthritis & Rheumatism

Cannabis and Cannabinoid ResearchNatural Compounds in Disease Treatment

Cited by 134

Prohedonic effect of cannabidiol in a rat model of depression

Shoval, G., Shbiro, L., Hershkovitz, L., Hazut, N., Zalsman, G., Mechoulam, R., & Weller, A. (2016) · Neuropsychobiology

Cannabis and Cannabinoid ResearchTreatment of Major Depression

Cited by 110

Cannabidiol presents an inverted U-shaped dose-response curve in the simulated public speaking test

Linares, I., Zuardi, A. W., Pereira, L. C. G., Queiroz, R. H. C., Mechoulam, R., Guimarães, F. S., & Crippa, J. A. S. (2016) · European Neuropsychopharmacology

Cannabis and Cannabinoid ResearchMedicinal Plant Extracts Effects

Cited by 31

HU-444, a Novel, Potent Anti-Inflammatory, Nonpsychotropic Cannabinoid

Haj, C. G., Sumariwalla, P. F., Hanuš, L., Kogan, N. M., Yektin, Z., Mechoulam, R., Feldmann, M., & Gallily, R. (2015) · The Journal of Pharmacology and Experimental Therapeutics

Cannabis and Cannabinoid ResearchInflammatory mediators and NSAID effects

Cited by 26

The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells

Dagon, Y., Avraham, Y., Link, G., Zolotarev, O., Mechoulam, R., & Berry, E. M. (2007) · Neurobiology of Disease

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 22