Feng, Zhaohui
Harvard University · Dana-Farber Cancer Institute
17 papers on CoChatORCID 0000-0002-8912-6456
Most cited papers
- Verified
The coordinate regulation of the p53 and mTOR pathways in cells
Feng, Z., Zhang, H., Levine, A. J., & Jin, S. (2005) · Proceedings of the National Academy of Sciences
PI3K/AKT/mTOR signaling in cancerCancer-related Molecular Pathways
Cited by 1,235
- Verified
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
Hu, W., Zhang, C., Wu, R., Sun, Y., Levine, A., & Feng, Z. (2010) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismCancer-related Molecular Pathways
Cited by 862
- Verified
Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats
Obici, S., Feng, Z., Karkanias, G., Baskin, D. G., & Rossetti, L. (2002) · Nature Neuroscience
Regulation of Appetite and ObesityHypothalamic control of reproductive hormones
Cited by 719
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Central Administration of Oleic Acid Inhibits Glucose Production and Food Intake
Obici, S., Feng, Z., Morgan, K., Stein, D., Karkanias, G., & Rossetti, L. (2002) · Diabetes
Regulation of Appetite and ObesityHypothalamic control of reproductive hormones
Cited by 654
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The Regulation of AMPK β1, TSC2, and PTEN Expression by p53: Stress, Cell and Tissue Specificity, and the Role of These Gene Products in Modulating the IGF-1-AKT-mTOR Pathways
Feng, Z., Hu, W., de Stanchina, E., Teresky, A. K., Jin, S., Lowe, S., & Levine, A. J. (2007) · Cancer Research
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 633
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Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production
Obici, S., Feng, Z., Arduini, A., Conti, R., & Rossetti, L. (2003) · Nature Medicine
Regulation of Appetite and ObesityPeroxisome Proliferator-Activated Receptors
Cited by 548
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Tumour-associated mutant p53 drives the Warburg effect
Zhang, C., Liu, J., Liang, Y., Wu, R., Zhao, Y., Hong, X., Lin, M., Yu, H., Liu, L., Levine, A. J., et al. (2013) · Nature Communications
Cancer, Hypoxia, and MetabolismCancer-related Molecular Pathways
Cited by 434
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Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
Zhang, C., Lin, M., Wu, R., Wang, X., Yang, B., Levine, A. J., Hu, W., & Feng, Z. (2011) · Proceedings of the National Academy of Sciences
Cancer-related Molecular PathwaysCancer, Hypoxia, and Metabolism
Cited by 431
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Central melanocortin receptors regulate insulin action
Obici, S., Feng, Z., Tan, J., Liu, L., Karkanias, G., & Rossetti, L. (2001) · Journal of Clinical Investigation
Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases
Cited by 370
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Overfeeding Rapidly Induces Leptin and Insulin Resistance
Wang, J., Obici, S., Morgan, K., Barzilai, N., Feng, Z., & Rossetti, L. (2001) · Diabetes
Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases
Cited by 355
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Coordination and communication between the p53 and IGF-1–AKT–TOR signal transduction pathways
Levine, A. J., Feng, Z., Mak, T. W., You, H., & Jin, S. (2006) · Genes & Development
PI3K/AKT/mTOR signaling in cancerCancer-related Molecular Pathways
Cited by 321
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Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy
Yue, X., Zhao, Y., Xu, Y., Zheng, M., Feng, Z., & Hu, W. (2017) · Journal of Molecular Biology
Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer
Cited by 308
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Declining p53 function in the aging process: A possible mechanism for the increased tumor incidence in older populations
Feng, Z., Hu, W., Teresky, A. K., Hernando, E., Cordon-Cardo, C., & Levine, A. J. (2007) · Proceedings of the National Academy of Sciences
Cancer-related Molecular PathwaysGenetics, Aging, and Longevity in Model Organisms
Cited by 264
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Chronic restraint stress attenuates p53 function and promotes tumorigenesis
Feng, Z., Liu, L., Zhang, C., Zheng, T., Wang, J., Lin, M., Zhao, Y., Wang, X., Levine, A. J., & Hu, W. (2012) · Proceedings of the National Academy of Sciences
Cancer-related Molecular PathwaysCancer, Stress, Anesthesia, and Immune Response
Cited by 209
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Cell of origin determines clinically relevant subtypes of MLL-rearranged AML
Krivtsov, A. V., Figueroa, M. E., Sinha, A. U., Stubbs, M. C., Feng, Z., Valk, P. J. M., Delwel, R., Döhner, K., Bullinger, L., Kung, A. L., et al. (2013) · Leukemia
Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes
Cited by 203
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Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans
Kang, H.-J., Feng, Z., Sun, Y., Atwal, G., Murphy, M. E., Rebbeck, T. R., Rosenwaks, Z., Levine, A. J., & Hu, W. (2009) · Proceedings of the National Academy of Sciences
Reproductive Biology and FertilityReproductive System and Pregnancy
Cited by 193
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High-resolution characterization of gene function using single-cell CRISPR tiling screen
Yang, L., Chan, A. K. N., Miyashita, K., Delaney, C. D., Wang, X., Li, H., Pokharel, S. P., Li, S., Li, M., Xu, X., et al. (2021) · Nature Communications
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 45
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