Pedersen, Oluf

A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene.

Højlund, K., Hansen, T., Lajer, M., Henriksen, J. E., Levin, K., Lindholm, J., Pedersen, O., & Beck-Nielsen, H. (2004) · Diabetes

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 130

Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease

Hitman, G. A., Hawrami, K., McCarthy, M. I., Viswanathan, M., Snehalatha, C., Ramachandran, A., Tuomilehto, J., Tuomilehto-Wolf, E., Nissinen, A., & Pedersen, O. (1995) · Diabetologia

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 124

Evidence of a liver–alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

Wewer Albrechtsen, N. J., Færch, K., Jensen, T. M., Witte, D. R., Pedersen, J., Mahendran, Y., Jonsson, A. E., Galsgaard, K. D., Winther-Sørensen, M., Torekov, S. S., et al. (2018) · Diabetologia

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 119

Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss

Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J.-E., Pedersen, O., Hansen, T., Madsbad, S., Holst, J. J., & Torekov, S. S. (2015) · International Journal of Obesity

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 118

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Wood, A. R., Jonsson, A., Jackson, A. U., Wang, N., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., et al. (2017) · Diabetes

Genetic Associations and EpidemiologyPancreatic function and diabetes

Cited by 117

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Cade, B. E., Gottlieb, D. J., Hruby, A., Jacques, P. F., Lamon-Fava, S., Richardson, K., et al. (2015) · The American Journal of Clinical Nutrition

Sleep and related disordersCircadian rhythm and melatonin

Cited by 112

Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models

Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., et al. (2023) · Nature Biotechnology

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 111

Intensive Integrated Therapy of Type 2 Diabetes

Gæde, P., & Pedersen, O. (2004) · Diabetes

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 108

Plasma N-terminal pro-brain natriuretic peptide as a major risk marker for cardiovascular disease in patients with type 2 diabetes and microalbuminuria

G�de, P., Hildebrandt, P., Hess, G., Parving, H.-H., & Pedersen, O. (2005) · Diabetologia

Heart Failure Treatment and ManagementChronic Kidney Disease and Diabetes

Cited by 105

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

Eriksson, J., Haring, R., Grarup, N., Vandenput, L., Wallaschofski, H., Lorentzen, E., Hansen, T., Mellström, D., Pedersen, O., Nauck, M., et al. (2017) · PLOS ONE

Hormonal and reproductive studiesGenetic Associations and Epidemiology

Cited by 101

Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus.

Vestergaard, H., Lund, S., Larsen, F. S., Bjerrum, O. J., & Pedersen, O. (1993) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 98

Predicting and elucidating the etiology of fatty liver disease: a machine learning modeling and validation study in the IMI DIRECT cohorts

Atabaki-Pasdar, N., Ohlsson, M., Viñuela, A., Frau, F., Pomares-Millan, H., Haid, M., Jones, A. G., Thomas, E. L., Koivula, R. W., Kurbasic, A., et al. (2020) · PLOS Medicine

Liver Disease Diagnosis and TreatmentAlcohol Consumption and Health Effects

Cited by 97

Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study

Oellgaard, J., Gæde, P., Rossing, P., Rørth, R., Køber, L., Parving, H.-H., & Pedersen, O. (2018) · Diabetologia

Diabetes Treatment and ManagementHeart Failure Treatment and Management

Cited by 86

A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin

Hansen, L., Hansen, T., Vestergaard, H., Bjørbæk, C., Echwald, S. M., Clausen, J. O., Chen, Y. H., Chen, M. X., Cohen, P. T. W., & Pedersen, O. (1995) · Human Molecular Genetics

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 84

KCNQ1 Long QT Syndrome Patients Have Hyperinsulinemia and Symptomatic Hypoglycemia

Torekov, S. S., Iepsen, E., Christiansen, M., Linneberg, A., Pedersen, O., Holst, J. J., Kanters, J. K., & Hansen, T. (2014) · Diabetes

Cardiac electrophysiology and arrhythmiasPancreatic function and diabetes

Cited by 84

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes

Xie, W., Wood, A. R., Lyssenko, V., Weedon, M. N., Knowles, J. W., Alkayyali, S., Assimes, T. L., Quertermous, T., Abbasi, F., Paananen, J., et al. (2013) · Diabetes

Genetic Associations and EpidemiologyMetabolomics and Mass Spectrometry Studies

Cited by 83

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., et al. (2024) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 79

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

Merino, J., Dashti, H. S., Li, S. X., Sarnowski, C., Justice, A. E., Graff, M., Papoutsakis, C., Smith, C. E., Dedoussis, G. V., Lemaitre, R. N., et al. (2019) · Molecular Psychiatry

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 66

Impaired Expression of Glycogen Synthase mRNA in Skeletal Muscle of NIDDM Patients

Vestergaard, H., Bjørbæk, C., Andersen, P. H., Bak, J. F., & Pedersen, O. (1991) · Diabetes

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 64

Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans

Hansen, T. H., Madsen, M. T. B., Jørgensen, N. R., Cohen, A. S., Hansen, T., Vestergaard, H., Pedersen, O., & Allin, K. H. (2018) · European Journal of Clinical Nutrition

Bone health and osteoporosis researchVitamin D Research Studies

Cited by 62

Genetic Variants in Promoters and Coding Regions of the Muscle Glycogen Synthase and the Insulin-Responsive GLUT4 Genes in NIDDM

Bjørbæk, C., Echwald, S. M., Hubricht, P., Vestergaard, H., Hansen, T., Zierath, J., & Pedersen, O. (1994) · Diabetes

Genetic Associations and EpidemiologyMetabolism, Diabetes, and Cancer

Cited by 61

Cloning of a Human Insulin-Stimulated Protein Kinase (ISPK-1) Gene and Analysis of Coding Regions and mRNA Levels of the ISPK-1 and the Protein Phosphatase-1 Genes in Muscle From NIDDM Patients

Bjørbæk, C., Vik, T. A., Echwald, S. M., Yang, P.-Y., Vestergaard, H., Wang, J. P., Webb, G. C., Richmond, K., Hansen, T., Erikson, R. L., et al. (1995) · Diabetes

Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus

Cited by 59

Association of the glycogen synthase locus on 19q13 with NIDDM in Pima Indians

Majer, M., Mott, D. M., Mochizuki, H., Rowles, J. C., Pedersen, O., Knowler, W. C., Bogardus, C., & Prochazka, M. (1996) · Diabetologia

Genetic Associations and EpidemiologyMetabolism, Diabetes, and Cancer

Cited by 53

Elevation of Serum Insulin Concentration During Euglycemic Hyperinsulinemic Clamp Studies Leads to Similar Activation of Insulin Receptor Kinase in Skeletal Muscle of Subjects With and Without NIDDM

Klein, H. H., Vestergaard, H., Kotzke, G., & Pedersen, O. (1995) · Diabetes

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 50