Espeland, Mark A.

Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial

Pahor, M., Guralnik, J. M., Ambrosius, W. T., Blair, S., Bonds, D. E., Church, T. S., Espeland, M. A., Fielding, R. A., Gill, T. M., Groessl, E. J., et al. (2014) · JAMA

Balance, Gait, and Falls PreventionFrailty in Older Adults

Cited by 1,427

Sodium Reduction and Weight Loss in the Treatment of Hypertension in Older Persons: A Randomized Controlled Trial of Nonpharmacologic Interventions in the Elderly (TONE)

Whelton, P. K., Appel, L. J., Espeland, M. A., Applegate, W. B., Ettinger, Jr., Kostis, J. B., Kumanyika, S., Lacy, C. R., Johnson, K. C., Folmar, S., et al. (1998) · JAMA

Sodium Intake and HealthBlood Pressure and Hypertension Studies

Cited by 1,200

Metformin as a tool to target aging

Barzilai, N., Crandall, J. P., Kritchevsky, S. B., & Espeland, M. A. (2016) · Cell Metabolism

Metabolism, Diabetes, and CancerGenetics, Aging, and Longevity in Model Organisms

Cited by 1,096

Effect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes: The CAROLINA Randomized Clinical Trial

Rosenstock, J., Kahn, S. E., Johansen, O. E., Zinman, B., Espeland, M. A., Woerle, H. J., Pfarr, E., Keller, A., Mattheus, M., Baanstra, D., et al. (2019) · JAMA

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 612

Physical rehabilitation for older patients hospitalized for heart failure

Kitzman, D. W., Whellan, D. J., Duncan, P., Pastva, A. M., Mentz, R. J., Reeves, G. R., Nelson, M. B., Chen, H., Upadhya, B., Reed, S. D., et al. (2021) · New England Journal of Medicine

Frailty in Older AdultsHeart Failure Treatment and Management

Cited by 594

World‐Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

Kivipelto, M., Mangialasche, F., Snyder, H. M., Allegri, R., Andrieu, S., Arai, H., Baker, L., Belleville, S., Brodaty, H., Brucki, S. M., et al. (2020) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchCognitive Abilities and Testing

Cited by 553

Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial

Sink, K. M., Espeland, M. A., Castro, C. M., Church, T., Cohen, R., Dodson, J. A., Guralnik, J., Hendrie, H. C., Jennings, J., Katula, J., et al. (2015) · JAMA

Dementia and Cognitive Impairment ResearchPhysical Activity and Health

Cited by 402

A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup

Justice, J. N., Ferrucci, L., Newman, A. B., Aroda, V. R., Bahnson, J. L., Divers, J., Espeland, M. A., Marcovina, S., Pollak, M. N., Kritchevsky, S. B., et al. (2018) · GeroScience

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 359

A practical solution to pseudoreplication bias in single-cell studies

Zimmerman, K. D., Espeland, M. A., & Langefeld, C. D. (2021) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 356

Pseudoreplication bias in single-cell studies; a practical solution

Zimmerman, K. D., Espeland, M. A., & Langefeld, C. D. (2020) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 332

Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial

Baker, L. D., Espeland, M. A., Whitmer, R. A., Snyder, H. M., Leng, X., Lovato, L., Papp, K. V., Yu, M., Kivipelto, M., Alexander, A. S., et al. (2025) · JAMA

Dementia and Cognitive Impairment ResearchNutritional Studies and Diet

Cited by 270

Sex biology contributions to vulnerability to Alzheimer's disease: a think tank convened by the Women's Alzheimer's Research Initiative

Snyder, H. M., Asthana, S., Bain, L., Brinton, R., Craft, S., Dubal, D. B., Espeland, M. A., Gatz, M., Mielke, M. M., Raber, J., et al. (2016) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchSex and Gender in Healthcare

Cited by 262

Design and baseline characteristics of the CARdiovascular Outcome Trial of LINAgliptin Versus Glimepiride in Type 2 Diabetes (CAROLINA ® )

Marx, N., Rosenstock, J., Kahn, S. E., Zinman, B., Kastelein, J. J., Lachin, J. M., Espeland, M. A., Bluhmki, E., Mattheus, M., Ryckaert, B., et al. (2015) · Diabetes and Vascular Disease Research

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 212

Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: the action for health in diabetes

Espeland, M. A., Glick, H. A., Bertoni, A., Brancati, F. L., Bray, G. A., Clark, J. M., Curtis, J. M., Egan, C., Evans, M., Foreyt, J. P., et al. (2014) · Diabetes Care

Diabetes Treatment and ManagementDiabetes Management and Education

Cited by 174

The Brain Chart of Aging: Machine‐learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans

Habes, M., Pomponio, R., Shou, H., Doshi, J., Mamourian, E., Erus, G., Nasrallah, I., Launer, L. J., Rashid, T., Bilgel, M., et al. (2021) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchCerebrovascular and genetic disorders

Cited by 173

Higher RBC EPA + DHA corresponds with larger total brain and hippocampal volumes: WHIMS-MRI Study

Pottala, J. V., Yaffe, K., Robinson, J. G., Espeland, M. A., Wallace, R., & Harris, W. S. (2014) · Neurology

Fatty Acid Research and HealthDementia and Cognitive Impairment Research

Cited by 169

Weight Loss Prevents Urinary Incontinence in Women With Type 2 Diabetes: Results From the Look AHEAD Trial

Phelan, S., Kanaya, A. M., Subak, L. L., Hogan, P. E., Espeland, M. A., Wing, R. R., Burgio, K. L., DiLillo, V., Gorin, A. A., West, D. S., et al. (2012) · Journal of Urology

Pelvic floor disorders treatmentsUrinary Bladder and Prostate Research

Cited by 107

Effects of cocoa extract and a multivitamin on cognitive function: a randomized clinical trial

Baker, L. D., Manson, J. E., Rapp, S. R., Sesso, H. D., Gaussoin, S. A., Shumaker, S. A., & Espeland, M. A. (2023) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchPhytochemicals and Antioxidant Activities

Cited by 88

Development of clinical trials to extend healthy lifespan

Justice, J. N., Niedernhofer, L., Robbins, P. D., Aroda, V. R., Espeland, M. A., Kritchevsky, S. B., Kuchel, G. A., & Barzilai, N. (2018) · Cardiovascular Endocrinology & Metabolism

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 84

Intensive weight loss intervention and cancer risk in adults with type 2 diabetes: Analysis of the look ahead randomized clinical trial

Look AHEAD Research Group, Yeh, H., Bantle, J. P., Cassidy‐Begay, M., Blackburn, G., Bray, G. A., Byers, T., Clark, J. M., Coday, M., Egan, C., et al. (2020) · Obesity

Cancer Risks and FactorsMetabolism, Diabetes, and Cancer

Cited by 82

Intensive weight loss intervention in older individuals: results from the Action for Health in Diabetes Type 2 diabetes mellitus trial

Espeland, M. A., Rejeski, W. J., West, D. S., Bray, G. A., Clark, J. M., Peters, A. L., Chen, H., Johnson, K. C., Horton, E. S., Hazuda, H. P., et al. (2013) · Journal of the American Geriatrics Society

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 66

Impact of multidomain lifestyle intervention on frailty through the lens of deficit accumulation in adults with type 2 diabetes mellitus

Simpson, F. R., Pajewski, N. M., Nicklas, B., Kritchevsky, S., Bertoni, A., Ingram, F., Ojeranti, D., Espeland, M. A., & Trial, F. T. I. F. A. A. I. O. A. D. A. S. O. T. A. F. H. I. D. (. A. (2020) · The Journals of Gerontology: Series A

Frailty in Older AdultsDiabetes Treatment and Management

Cited by 66

Impact of intensive lifestyle intervention on disability-free life expectancy: the Look AHEAD study

Gregg, E. W., Lin, J., Bardenheier, B., Chen, H., Rejeski, W. J., Zhuo, X., Hergenroeder, A. L., Kritchevsky, S. B., Peters, A. L., Wagenknecht, L. E., et al. (2018) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 64

Effect of a long-term intensive lifestyle intervention on cognitive function: Action for Health in Diabetes study

Rapp, S. R., Luchsinger, J. A., Baker, L. D., Blackburn, G. L., Hazuda, H. P., Demos‐McDermott, K. E., Jeffery, R. W., Keller, J. N., McCaffery, J. M., Pajewski, N. M., et al. (2017) · Journal of the American Geriatrics Society

Dementia and Cognitive Impairment ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 62