Smith, Colin

Small vessel disease: mechanisms and clinical implications

Wardlaw, J. M., Smith, C., & Dichgans, M. (2019) · The Lancet Neurology

Cerebrovascular and genetic disordersNeurological Disease Mechanisms and Treatments

Cited by 1,777

Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging

Wardlaw, J. M., Smith, C., & Dichgans, M. (2013) · The Lancet Neurology

Cerebrovascular and genetic disordersNeurological Disease Mechanisms and Treatments

Cited by 1,657

Neuroimaging standards for research into small vessel disease—advances since 2013

Duering, M., Biessels, G. J., Brodtmann, A., Chen, C., Cordonnier, C., de Leeuw, F.-E., Debette, S., Frayne, R., Jouvent, E., Rost, N. S., et al. (2023) · The Lancet Neurology

Cerebrovascular and genetic disordersNeurological Disease Mechanisms and Treatments

Cited by 1,144

Common genetic variants influence human subcortical brain structures

Initiative, T. A. D. N., Hibar, D. P., The CHARGE Consortium, EPIGEN, IMAGEN, SYS, Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., et al. (2015) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 858

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

the Alzheimer’s Disease Neuroimaging Initiative, E. C., Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., et al. (2014) · Brain Imaging and Behavior

Genetic Associations and EpidemiologyFunctional Brain Connectivity Studies

Cited by 838

The transcriptional landscape of age in human peripheral blood

Peters, M. J., Joehanes, R., Pilling, L. C., Schurmann, C., Conneely, K. N., Powell, J., Reinmaa, E., Sutphin, G. L., Zhernakova, A., Schramm, K., et al. (2015) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsEpigenetics and DNA Methylation

Cited by 725

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

Charidimou, A., Boulouis, G., Frosch, M. P., Baron, J.-C., Pasi, M., Albucher, J. F., Banerjee, G., Barbato, C., Bonneville, F., Brandner, S., et al. (2022) · The Lancet Neurology

Intracerebral and Subarachnoid Hemorrhage ResearchCerebrovascular and genetic disorders

Cited by 723

Genetic variability in the regulation of gene expression in ten regions of the human brain

UK Brain Expression Consortium, Ramasamy, A., North American Brain Expression Consortium, Trabzuni, D., Guelfi, S., Varghese, V., Smith, C., Walker, R., De, T., Coin, L., et al. (2014) · Nature Neuroscience

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 644

Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome

Illingworth, R. S., Gruenewald-Schneider, U., Webb, S., Kerr, A. R. W., James, K. D., Turner, D. J., Smith, C., Harrison, D. J., Andrews, R., & Bird, A. P. (2010) · PLoS Genetics

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 550

Aging-related tau astrogliopathy (ARTAG): Harmonized evaluation strategy

Kovacs, G. G., Ferrer, I., Grinberg, L. T., Alafuzoff, I., Attems, J., Budka, H., Cairns, N. J., Crary, J. F., Duyckaerts, C., Ghetti, B., et al. (2016) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 532

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

Cruchaga, C., Karch, C. M., Jin, S. C., Benitez, B. A., Cai, Y., Guerreiro, R., Harari, O., Norton, J., Budde, J., Bertelsen, S., et al. (2014) · Nature

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 461

Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

Soreq, L., Rose, J., Soreq, E., Hardy, J., Trabzuni, D., Cookson, M. R., Smith, C., Ryten, M., Patani, R., & Ule, J. (2017) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 419

Long-term intracerebral inflammatory response after traumatic brain injury

Gentleman, S. M., Leclercq, P. D., Moyes, L., Graham, D. I., Smith, C., Griffin, W. S. T., & Nicoll, J. A. R. (2004) · Forensic Science International

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 272

MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies

Trabzuni, D., Wray, S., Vandrovcova, J., Ramasamy, A., Walker, R., Smith, C., Luk, C., Gibbs, J. R., Dillman, A., Hernandez, D. G., et al. (2012) · Human Molecular Genetics

Alzheimer's disease research and treatmentsRNA Research and Splicing

Cited by 252

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

Trabzuni, D., Ryten, M., Walker, R., Smith, C., Imran, S., Ramasamy, A., Weale, M. E., & Hardy, J. (2011) · Journal of Neurochemistry

Molecular Biology Techniques and ApplicationsGene expression and cancer classification

Cited by 229

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology

Jiwaji, Z., Tiwari, S. S., Avilés-Reyes, R. X., Hooley, M., Hampton, D., Torvell, M., Johnson, D. A., McQueen, J., Baxter, P., Sabari-Sankar, K., et al. (2022) · Nature Communications

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 223

Insights into TREM2 biology by network analysis of human brain gene expression data

Forabosco, P., Ramasamy, A., Trabzuni, D., Walker, R., Smith, C., Bras, J., Levine, A. P., Hardy, J., Pocock, J. M., Guerreiro, R., et al. (2013) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 180

Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer’s Disease

Pickett, E. K., Herrmann, A. G., McQueen, J., Abt, K., Dando, O., Tulloch, J., Jain, P., Dunnett, S., Sohrabi, S., Fjeldstad, M. P., et al. (2019) · Cell Reports

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 179

Pathology of Lacunar Ischemic Stroke in Humans—A Systematic Review

Bailey, E. L., Smith, C., Sudlow, C. L. M., & Wardlaw, J. M. (2012) · Brain Pathology

Acute Ischemic Stroke ManagementIntracerebral and Subarachnoid Hemorrhage Research

Cited by 178

Effects of Antemortem and Postmortem Variables on Human Brain mRNA Quality: A BrainNet Europe Study

Durrenberger, P. F., Fernando, S., Kashefi, S. N., Ferrer, I., Hauw, J.-J., Seilhean, D., Smith, C., Walker, R., Al-Sarraj, S., Troakes, C., et al. (2010) · Journal of Neuropathology & Experimental Neurology

Molecular Biology Techniques and ApplicationsRNA Research and Splicing

Cited by 161

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health.

SenNet Consortium, Writing Group, Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., et al. (2022) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 122

Tau immunohistochemistry in acute brain injury

Smith, C., Graham, D. I., Murray, L. S., & Nicoll, J. A. R. (2003) · Neuropathology and Applied Neurobiology

Traumatic Brain Injury ResearchAlzheimer's disease research and treatments

Cited by 110

Is the Spontaneously Hypertensive Stroke Prone Rat a Pertinent Model of Sub Cortical Ischemic Stroke? A Systematic Review

Bailey, E. L., Smith, C., Sudlow, C. L. M., & Wardlaw, J. M. (2011) · International Journal of Stroke

Neurological Disease Mechanisms and TreatmentsAcute Ischemic Stroke Management

Cited by 102

Cerebral small vessel endothelial structural changes predate hypertension in stroke prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5-to 21-week old rats

Bailey, E. L., Wardlaw, J. M., Graham, D., Dominiczak, A. F., Sudlow, C. L. M., & Smith, C. (2011) · Neuropathology and Applied Neurobiology

Barrier Structure and Function StudiesCerebrovascular and genetic disorders

Cited by 100