Pinton, Paolo

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 6,680

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca 2+ Responses

Rizzuto, R., Pinton, P., Carrington, W., Fay, F. S., Fogarty, K. E., Lifshitz, L. M., Tuft, R. A., & Pozzan, T. (1998) · Science

Mitochondrial Function and PathologyIon Channels and Receptors

Cited by 2,257

Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis

Giorgio, M., Migliaccio, E., Orsini, F., Paolucci, D., Moroni, M., Contursi, C., Pelliccia, G., Luzi, L., Minucci, S., Marcaccio, M., et al. (2005) · Cell

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 1,176

Regulation of autophagy by cytoplasmic p53

Tasdemir, E., Maiuri, M. C., Galluzzi, L., Vitale, I., Djavaheri-Mergny, M., D'Amelio, M., Criollo, A., Morselli, E., Zhu, C., Harper, F., et al. (2008) · Nature Cell Biology

Autophagy in Disease and TherapyCancer-related Molecular Pathways

Cited by 1,132

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., et al. (2015) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 1,002

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

Wieckowski, M. R., Giorgi, C., Lebiedzinska, M., Duszynski, J., & Pinton, P. (2009) · Nature Protocols

Mitochondrial Function and PathologyIon Channels and Receptors

Cited by 979

The machineries, regulation and cellular functions of mitochondrial calcium

Giorgi, C., Marchi, S., & Pinton, P. (2018) · Nature Reviews Molecular Cell Biology

Mitochondrial Function and PathologyCalcium signaling and nucleotide metabolism

Cited by 941

ATP synthesis and storage

Bonora, M., Patergnani, S., Rimessi, A., De Marchi, E., Suski, J. M., Bononi, A., Giorgi, C., Marchi, S., Missiroli, S., Poletti, F., et al. (2012) · Purinergic Signalling

Adenosine and Purinergic SignalingATP Synthase and ATPases Research

Cited by 644

The Golgi apparatus is an inositol 1,4,5‐trisphosphate‐sensitive Ca2+ store, with functional properties distinct from those of the endoplasmic reticulum

Pinton, P., Pozzan, T., & Rizzuto, R. (1998) · The EMBO Journal

Calcium signaling and nucleotide metabolismIon Channels and Receptors

Cited by 435

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

Bonora, M., Wieckowski, M. R., Chinopoulos, C., Kepp, O., Kroemer, G., Galluzzi, L., & Pinton, P. (2015) · Oncogene

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 330

PTEN Counteracts FBXL2 to Promote IP3R3- and Ca2+-Mediated Apoptosis Limiting Tumour Growth

Kuchay, S., Giorgi, C., Simoneschi, D., Pagan, J., Missiroli, S., Saraf, A., Florens, L., Washburn, M. P., Collazo-Lorduy, A., Castillo-Martin, M., et al. (2017) · Nature

Cell death mechanisms and regulationIon Channels and Receptors

Cited by 251

Ca2+ Fluxes and Cancer

Marchi, S., Giorgi, C., Galluzzi, L., & Pinton, P. (2020) · Molecular Cell

Ion Channels and ReceptorsCalcium signaling and nucleotide metabolism

Cited by 235

Mitochondria in non-alcoholic fatty liver disease

Simões, I. C. M., Fontes, A., Pinton, P., Zischka, H., & Wieckowski, M. R. (2018) · The International Journal of Biochemistry & Cell Biology

Liver Disease Diagnosis and TreatmentMitochondrial Function and Pathology

Cited by 234

The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein

Franceschini, A., Capece, M., Chiozzi, P., Falzoni, S., Sanz, J. M., Sarti, A. C., Bonora, M., Pinton, P., & Di Virgilio, F. (2015) · The FASEB Journal

Adenosine and Purinergic SignalingInflammasome and immune disorders

Cited by 225

The Mitochondrial Permeability Transition Pore and Cancer: Molecular Mechanisms Involved in Cell Death

Bonora, M., & Pinton, P. (2014) · Frontiers in Oncology

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 208

Mitochondrial Function and Dysfunction in Dilated Cardiomyopathy

Ramaccini, D., Montoya-Uribe, V., Aan, F. J., Modesti, L., Potes, Y., Wieckowski, M. R., Krga, I., Glibetić, M., Pinton, P., Giorgi, C., et al. (2021) · Frontiers in Cell and Developmental Biology

Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion

Cited by 136

Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology

Bonora, M., Patergnani, S., Ramaccini, D., Morciano, G., Pedriali, G., Kahsay, A., Bouhamida, E., Giorgi, C., Wieckowski, M., & Pinton, P. (2020) · Biomolecules

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 135

Germline BAP1 mutations induce a Warburg effect

Bononi, A., Yang, H., Giorgi, C., Patergnani, S., Pellegrini, L., Su, M., Xie, G., Signorato, V., Pastorino, S., Morris, P., et al. (2017) · Cell Death & Differentiation

Cancer, Hypoxia, and MetabolismChromatin Remodeling and Cancer

Cited by 133

Metformin Prevents Glucose-Induced Protein Kinase C-β2 Activation in Human Umbilical Vein Endothelial Cells Through an Antioxidant Mechanism

Gallo, A., Ceolotto, G., Pinton, P., Iori, E., Murphy, E., Rutter, G. A., Rizzuto, R., Semplicini, A., & Avogaro, A. (2005) · Diabetes

Metabolism, Diabetes, and CancerAdvanced Glycation End Products research

Cited by 95

The Interplay of Hypoxia Signaling on Mitochondrial Dysfunction and Inflammation in Cardiovascular Diseases and Cancer: From Molecular Mechanisms to Therapeutic Approaches

Bouhamida, E., Morciano, G., Perrone, M., Kahsay, A. E., Della Sala, M., Wieckowski, M. R., Fiorica, F., Pinton, P., Giorgi, C., & Patergnani, S. (2022) · Biology

Cancer, Hypoxia, and MetabolismCardiac Ischemia and Reperfusion

Cited by 87

Differential recruitment of PKC isoforms in HeLa cells during redox stress

Rimessi, A., Rizzuto, R., & Pinton, P. (2007) · Cell Stress & Chaperones

Protein Kinase Regulation and GTPase SignalingRedox biology and oxidative stress

Cited by 27

TFG binds LC3C to regulate ULK1 localization and autophagosome formation

Carinci, M., Testa, B., Bordi, M., Milletti, G., Bonora, M., Antonucci, L., Ferraina, C., Carro, M., Kumar, M., Ceglie, D., et al. (2021) · The EMBO Journal

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 25