Krystal, John H.

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H. J., Nurnberger, J. I., et al. (2017) · JAMA Psychiatry

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 90

Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients

Cavus, I., Pan, J. W., Hetherington, H. P., Abi‐Saab, W., Zaveri, H. P., Vives, K. P., Krystal, J. H., Spencer, S. S., & Spencer, D. D. (2008) · Epilepsia

Epilepsy research and treatmentNeuroscience and Neuropharmacology Research

Cited by 89

Real-time fMRI neurofeedback with War Veterans with chronic PTSD: a feasibility study

Gerin, M. I., Fichtenholtz, H., Roy, A., Walsh, C. J., Krystal, J. H., Southwick, S., & Hampson, M. (2016) · Frontiers in Psychiatry

Posttraumatic Stress Disorder ResearchTraumatic Brain Injury Research

Cited by 84

Maintenance of antidepressant and antisuicidal effects by D-cycloserine among patients with treatment-resistant depression who responded to low-dose ketamine infusion: a double-blind randomized placebo–control study

Chen, M.-H., Cheng, C.-M., Gueorguieva, R., Lin, W.-C., Li, C.-T., Hong, C.-J., Tu, P.-C., Bai, Y.-M., Tsai, S.-J., Krystal, J. H., et al. (2019) · Neuropsychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 84

The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects

Hallak, J. E. C., Dursun, S. M., Bosi, D. C., de Macedo, L. R. H., Machado-de-Sousa, J. P., Abrão, J., Crippa, J. A. S., McGuire, P., Krystal, J. H., Baker, G. B., et al. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Cannabis and Cannabinoid ResearchPsychedelics and Drug Studies

Cited by 83

Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress

Licznerski, P., Duric, V., Banasr, M., Alavian, K. N., Ota, K. T., Kang, H. J., Jonas, E. A., Ursano, R., Krystal, J. H., Duman, R. S., et al. (2015) · PLOS Biology

Posttraumatic Stress Disorder ResearchStress Responses and Cortisol

Cited by 79

Imaging the effect of ketamine on synaptic density (SV2A) in the living brain

Holmes, S. E., Finnema, S. J., Naganawa, M., DellaGioia, N., Holden, D., Fowles, K., Davis, M., Ropchan, J., Emory, P., Ye, Y., et al. (2022) · Molecular Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 78

Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia.

Krystal, J. H., Tolin, D. F., Sanacora, G., Castner, S. A., Williams, G. V., Aikins, D. E., Hoffman, R. E., & D'Souza, D. C. (2009) · Drug Discovery Today

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 76

Minimal clinically important differences (MCID) in assessing outcomes of post-traumatic stress disorder

Stefanovics, E. A., Rosenheck, R. A., Jones, K. M., Huang, G., & Krystal, J. H. (2018) · Psychiatric Quarterly

Posttraumatic Stress Disorder ResearchPsychometric Methodologies and Testing

Cited by 74

Multimodal Investigation of Network Level Effects Using Intrinsic Functional Connectivity, Anatomical Covariance, and Structure-to-Function Correlations in Unmedicated Major Depressive Disorder

Scheinost, D., Holmes, S. E., DellaGioia, N., Schleifer, C., Matuskey, D., Abdallah, C. G., Hampson, M., Krystal, J. H., Anticevic, A., & Esterlis, I. (2018) · Neuropsychopharmacology

Functional Brain Connectivity StudiesTreatment of Major Depression

Cited by 73

A placebo-controlled, cross-over trial of lamotrigine in depersonalization disorder

Sierra, M., Phillips, M. L., Ivin, G., Krystal, J., & David, A. S. (2003) · Journal of Psychopharmacology

Psychosomatic Disorders and Their TreatmentsTreatment of Major Depression

Cited by 73

Characteristics of panic attack subtypes: Assessment of spontaneous panic, situational panic, sleep panic, and limited symptom attacks

Krystal, J. H., Woods, S. W., Hill, C. L., & Charney, D. S. (1991) · Comprehensive Psychiatry

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychosomatic Disorders and Their Treatments

Cited by 73

Trajectories of relapse in randomised, placebo-controlled trials of treatment discontinuation in major depressive disorder: An individual patient-level data meta-analysis

Gueorguieva, R., Chekroud, A. M., & Krystal, J. H. (2017) · The Lancet Psychiatry

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 67

Similar psychotic and cognitive profile between ketamine dependence with persistent psychosis and schizophrenia

Cheng, W.-J., Chen, C.-H., Chen, C.-K., Huang, M.-C., Pietrzak, R. H., Krystal, J. H., & Xu, K. (2018) · Schizophrenia Research

Schizophrenia research and treatmentForensic Toxicology and Drug Analysis

Cited by 65

A New Rapid-Acting Antidepressant

Krystal, J. H., Charney, D. S., & Duman, R. S. (2020) · Cell

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 63

MDMA and MDMA-assisted therapy

Wolfgang, A. S., Fonzo, G. A., Gray, J. C., Krystal, J. H., Grzenda, A., Widge, A. S., Kraguljac, N. V., McDonald, W. M., Rodriguez, C. I., & Nemeroff, C. B. (2025) · American Journal of Psychiatry

Psychedelics and Drug StudiesPosttraumatic Stress Disorder Research

Cited by 62

The Association of PTSD Symptom Severity With Localized Hippocampus and Amygdala Abnormalities

Akiki, T. J., Averill, C. L., Wrocklage, K. M., Schweinsburg, B., Scott, J. C., Martini, B., Averill, L. A., Southwick, S. M., Krystal, J. H., & Abdallah, C. G. (2017) · Chronic Stress

Posttraumatic Stress Disorder ResearchTraumatic Brain Injury Research

Cited by 58

Late-Life Exacerbation of PTSD Symptoms in US Veterans: Results From the National Health and Resilience in Veterans Study

Mota, N., Tsai, J., Kirwin, P. D., Harpaz-Rotem, I., Krystal, J. H., Southwick, S. M., & Pietrzak, R. H. (2016) · The Journal of Clinical Psychiatry

Posttraumatic Stress Disorder ResearchTraumatic Brain Injury Research

Cited by 57

Clinical and Financial Outcomes Associated With a Workplace Mental Health Program Before and During the COVID-19 Pandemic

Bondar, J., Babich Morrow, C., Gueorguieva, R., Brown, M., Hawrilenko, M., Krystal, J. H., Corlett, P. R., & Chekroud, A. M. (2022) · JAMA Network Open

Workplace Health and Well-beingDigital Mental Health Interventions

Cited by 53

Metabotropic Glutamatergic Receptor 5 and Stress Disorders: Knowledge Gained From Receptor Imaging Studies

Esterlis, I., Holmes, S. E., Sharma, P., Krystal, J. H., & DeLorenzo, C. (2018) · Biological Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 50

Role of N-Methyl D-aspartate receptors in action-based predictive coding deficits in schizophrenia

Kort, N. S., Ford, J. M., Roach, B. J., Gunduz-Bruce, H., Krystal, J. H., Jaeger, J., Reinhart, R. M. G., & Mathalon, D. H. (2017) · Biological Psychiatry

Schizophrenia research and treatmentMental Health and Psychiatry

Cited by 48

International Task Force on Benzodiazepines

Balon, R., Chouinard, G., Cosci, F., Dubovsky, S. L., Fava, G. A., Freire, R. C., Greenblatt, D. J., Krystal, J. H., Nardi, A. E., Rickels, K., et al. (2018) · Psychotherapy and Psychosomatics

Pharmaceutical Practices and Patient OutcomesAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 35

mTORC1 inhibitor effects on rapid ketamine-induced reductions in suicidal ideation in patients with treatment-resistant depression

Averill, L. A., Averill, C. L., Gueorguieva, R., Fouda, S., Sherif, M., Ahn, K.-H., Ranganathan, M., D'Souza, D. C., Southwick, S. M., Sanacora, G., et al. (2022) · Journal of Affective Disorders

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 33

β2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder

Czermak, C., Staley, J. K., Kasserman, S., Bois, F., Young, T., Henry, S., Tamagnan, G. D., Seibyl, J. P., Krystal, J. H., & Neumeister, A. (2008) · The International Journal of Neuropsychopharmacology

Nicotinic Acetylcholine Receptors StudyPosttraumatic Stress Disorder Research

Cited by 31