Krystal, John H.

Probing the pathophysiology of auditory/verbal hallucinations by combining functional magnetic resonance imaging and transcranial magnetic stimulation

Hoffman, R. E., Hampson, M., Wu, K., Anderson, A. W., Gore, J. C., Buchanan, R. J., Constable, R. T., Hawkins, K. A., Sahay, N., & Krystal, J. H. (2007) · Cerebral Cortex

Transcranial Magnetic Stimulation StudiesHallucinations in medical conditions

Cited by 169

Preliminary evidence for medication effects on functional abnormalities in the amygdala and anterior cingulate in bipolar disorder

Blumberg, H. P., Donegan, N. H., Sanislow, C. A., Collins, S., Lacadie, C., Skudlarski, P., Gueorguieva, R., Fulbright, R. K., McGlashan, T. H., Gore, J. C., et al. (2005) · Psychopharmacology

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 165

Effects of Ketamine in Treatment-Refractory Obsessive-Compulsive Disorder

Bloch, M. H., Wasylink, S., Landeros-Weisenberger, A., Panza, K. E., Billingslea, E., Leckman, J. F., Krystal, J. H., Bhagwagar, Z., Sanacora, G., & Pittenger, C. (2012) · Biological Psychiatry

Obsessive-Compulsive Spectrum DisordersTreatment of Major Depression

Cited by 162

Association of Combined Naltrexone and Ketamine With Depressive Symptoms in a Case series of Patients With Depression and Alcohol Use Disorder

Yoon, G., Petrakis, I. L., & Krystal, J. H. (2019) · JAMA Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 155

Association of a Prior Psychiatric Diagnosis With Mortality Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Infection

Li, L., Li, F., Fortunati, F., & Krystal, J. H. (2020) · JAMA Network Open

COVID-19 Clinical Research StudiesCOVID-19 and Mental Health

Cited by 154

Reduced global functional connectivity of the medial prefrontal cortex in major depressive disorder

Murrough, J. W., Abdallah, C. G., Anticevic, A., Collins, K. A., Geha, P., Averill, L. A., Schwartz, J., DeWilde, K. E., Averill, C., Jia‐Wei Yang, G., et al. (2016) · Human Brain Mapping

Functional Brain Connectivity StudiesTreatment of Major Depression

Cited by 153

Functional hierarchy underlies preferential connectivity disturbances in schizophrenia

Yang, G. J., Murray, J. D., Wang, X.-J., Glahn, D. C., Pearlson, G. D., Repovs, G., Krystal, J. H., & Anticevic, A. (2016) · Proceedings of the National Academy of Sciences

Functional Brain Connectivity StudiesSchizophrenia research and treatment

Cited by 153

The Impact of NMDA Receptor Blockade on Human Working Memory-Related Prefrontal Function and Connectivity

Driesen, N. R., McCarthy, G., Bhagwagar, Z., Bloch, M. H., Calhoun, V. D., D'Souza, D. C., Gueorguieva, R., He, G., Leung, H.-C., Ramani, R., et al. (2013) · Neuropsychopharmacology

Neural and Behavioral Psychology StudiesNeuroscience and Neuropharmacology Research

Cited by 148

Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression

Esterlis, I., DellaGioia, N., Pietrzak, R. H., Matuskey, D., Nabulsi, N., Abdallah, C. G., Yang, J., Pittenger, C., Sanacora, G., Krystal, J. H., et al. (2018) · Molecular Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 148

Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic

Krystal, J. H., Abdallah, C. G., Averill, L. A., Kelmendi, B., Harpaz-Rotem, I., Sanacora, G., Southwick, S. M., & Duman, R. S. (2017) · Current Psychiatry Reports

Posttraumatic Stress Disorder ResearchTreatment of Major Depression

Cited by 145

Efficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode: A Systematic Review and Meta-analysis

Rhee, T. G., Shim, S. R., Forester, B. P., Nierenberg, A. A., McIntyre, R. S., Papakostas, G. I., Krystal, J. H., Sanacora, G., & Wilkinson, S. T. (2022) · JAMA Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 141

RETRACTED: Impaired Visual Cortical Plasticity in Schizophrenia

Çavuş, I., Reinhart, R. M. G., Roach, B. J., Gueorguieva, R., Teyler, T. J., Clapp, W. C., Ford, J. M., Krystal, J. H., & Mathalon, D. H. (2012) · Biological Psychiatry

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 130

Neurobiological aspects of PTSD: review of clinical and preclinical studies

Krystal, J. H., Kosten, T. R., Southwick, S., Mason, J. W., Perry, B. D., & Giller, E. L. (1989) · Behavior Therapy

Posttraumatic Stress Disorder ResearchStress Responses and Cortisol

Cited by 121

Ketamine as a promising prototype for a new generation of rapid‐acting antidepressants

Abdallah, C. G., Averill, L. A., & Krystal, J. H. (2015) · Annals of the New York Academy of Sciences

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 121

Impairment of working memory maintenance and response in schizophrenia: functional magnetic resonance imaging evidence

Driesen, N. R., Leung, H.-C., Calhoun, V. D., Constable, R. T., Gueorguieva, R., Hoffman, R., Skudlarski, P., Goldman-Rakic, P. S., & Krystal, J. H. (2008) · Biological Psychiatry

Schizophrenia research and treatmentNeural and Behavioral Psychology Studies

Cited by 119

Psychiatric safety of ketamine in psychopharmacology research

Perry, E. B., Cramer, J. A., Cho, H.-S., Petrakis, I. L., Karper, L. P., Genovese, A., O’Donnell, E., Krystal, J. H., D’Souza, D. C., & Yale Ketamine Study Group (2007) · Psychopharmacology

Treatment of Major DepressionPsychedelics and Drug Studies

Cited by 117

Prefrontal Connectivity and Glutamate Transmission: Relevance to Depression Pathophysiology and Ketamine Treatment

Abdallah, C. G., Averill, C. L., Salas, R., Averill, L. A., Baldwin, P. R., Krystal, J. H., Mathew, S. J., & Mathalon, D. H. (2017) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Treatment of Major DepressionFunctional Brain Connectivity Studies

Cited by 111

Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial

Abdallah, C. G., Roache, J. D., Gueorguieva, R., Averill, L. A., Young-McCaughan, S., Shiroma, P. R., Purohit, P., Brundige, A., Murff, W., Ahn, K.-H., et al. (2022) · Neuropsychopharmacology

Posttraumatic Stress Disorder ResearchTreatment of Major Depression

Cited by 111

Comorbidity of psychiatric and substance abuse disorders

George, T. P., & Krystal, J. H. (2000) · Current Opinion in Psychiatry

Substance Abuse Treatment and OutcomesSchizophrenia research and treatment

Cited by 106

Ketamine effects on memory reconsolidation favor a learning model of delusions

Corlett, P. R., Cambridge, V., Gardner, J. M., Piggot, J. S., Turner, D. C., Everitt, J. C., Arana, F. S., Morgan, H. L., Milton, A. L., Lee, J. L., et al. (2013) · PLoS ONE

Memory and Neural MechanismsMemory Processes and Influences

Cited by 105

Relationship between ketamine-induced psychotic symptoms and NMDA receptor occupancy—a [123I]CNS-1261 SPET study

Stone, J. M., Erlandsson, K., Arstad, E., Squassante, L., Teneggi, V., Bressan, R. A., Krystal, J. H., Ell, P. J., & Pilowsky, L. S. (2008) · Psychopharmacology

Schizophrenia research and treatmentTreatment of Major Depression

Cited by 103

Utility of Imaging-Based Biomarkers for Glutamate-Targeted Drug Development in Psychotic Disorders: A Randomized Clinical Trial

Javitt, D. C., Carter, C. S., Krystal, J. H., Kantrowitz, J. T., Girgis, R. R., Kegeles, L. S., Ragland, J. D., Maddock, R. J., Lesh, T. A., Tanase, C., et al. (2018) · JAMA Psychiatry

Schizophrenia research and treatmentTreatment of Major Depression

Cited by 100

Glutamatergic Modulation of Auditory Information Processing in the Human Brain

Gunduz-Bruce, H., Reinhart, R. M. G., Roach, B. J., Gueorguieva, R., Oliver, S., D'Souza, D. C., Ford, J. M., Krystal, J. H., & Mathalon, D. H. (2012) · Biological Psychiatry

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 93

Reduced amygdala serotonin transporter binding in posttraumatic stress disorder

Murrough, J. W., Huang, Y., Hu, J., Henry, S., Williams, W., Gallezot, J.-D., Bailey, C. R., Krystal, J. H., Carson, R. E., & Neumeister, A. (2011) · Biological Psychiatry

Posttraumatic Stress Disorder ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 92