Otto, Markus

Fluid biomarkers in frontotemporal dementia: past, present and future

Swift, I. J., Sogorb-Esteve, A., Heller, C., Synofzik, M., Otto, M., Graff, C., Galimberti, D., Todd, E., Heslegrave, A. J., van der Ende, E. L., et al. (2021) · Journal of Neurology, Neurosurgery & Psychiatry

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 122

Poly‐GP in cerebrospinal fluid links C9orf72‐associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD

Lehmer, C., Oeckl, P., Weishaupt, J. H., Volk, A. E., Diehl‐Schmid, J., Schroeter, M. L., Lauer, M., Kornhuber, J., Levin, J., Fassbender, K., et al. (2017) · EMBO Molecular Medicine

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 118

Serum neurofilament light chain in behavioral variant frontotemporal dementia

Steinacker, P., Anderl-Straub, S., Diehl-Schmid, J., Semler, E., Uttner, I., von Arnim, C. A. F., Barthel, H., Danek, A., Fassbender, K., Fliessbach, K., et al. (2018) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 116

Neuronal pentraxins as biomarkers of synaptic activity: from physiological functions to pathological changes in neurodegeneration

Gómez de San José, N., Massa, F., Halbgebauer, S., Oeckl, P., Steinacker, P., & Otto, M. (2022) · Journal of Neural Transmission

Biomarkers in Disease MechanismsNeuroscience and Neuropharmacology Research

Cited by 112

Plasma neurofilament light for prediction of disease progression in familial frontotemporal lobar degeneration

Rojas, J. C., Wang, P., Staffaroni, A. M., Heller, C., Cobigo, Y., Wolf, A., Goh, S.-Y. M., Ljubenkov, P. A., Heuer, H. W., Fong, J. C., et al. (2021) · Neurology

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 106

Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia

van der Ende, E. L., Xiao, M., Xu, D., Poos, J. M., Panman, J. L., Jiskoot, L. C., Meeter, L. H., Dopper, E. G., Papma, J. M., Heller, C., et al. (2020) · Journal of Neurology, Neurosurgery & Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 94

Serum GFAP differentiates Alzheimer’s disease from frontotemporal dementia and predicts MCI-to-dementia conversion

Oeckl, P., Anderl-Straub, S., Von Arnim, C. A. F., Baldeiras, I., Diehl-Schmid, J., Grimmer, T., Halbgebauer, S., Kort, A. M., Lima, M., Marques, T. M., et al. (2022) · Journal of Neurology, Neurosurgery & Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 94

Incidence of Syndromes Associated With Frontotemporal Lobar Degeneration in 9 European Countries

Logroscino, G., Piccininni, M., Graff, C., Hardiman, O., Ludolph, A. C., Moreno, F., Otto, M., Remes, A. M., Rowe, J. B., Seelaar, H., et al. (2023) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 91

Glial fibrillary acidic protein as blood biomarker for differential diagnosis and severity of major depressive disorder

Steinacker, P., Al Shweiki, M. R., Oeckl, P., Graf, H., Ludolph, A. C., Schönfeldt-Lecuona, C., & Otto, M. (2021) · Journal of Psychiatric Research

Treatment of Major DepressionTryptophan and brain disorders

Cited by 84

Identification of novel cerebrospinal fluid biomarker candidates for dementia with Lewy bodies: a proteomic approach

van Steenoven, I., Koel-Simmelink, M. J. A., Vergouw, L. J. M., Tijms, B. M., Piersma, S. R., Pham, T. V., Bridel, C., Ferri, G.-L., Cocco, C., Noli, B., et al. (2020) · Molecular Neurodegeneration

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 83

Predicting behavioral variant frontotemporal dementia with pattern classification in multi-center structural MRI data

Meyer, S., Mueller, K., Stuke, K., Bisenius, S., Diehl-Schmid, J., Jessen, F., Kassubek, J., Kornhuber, J., Ludolph, A. C., Prudlo, J., et al. (2017) · NeuroImage: Clinical

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 83

Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt–Jakob disease

Buerger, K., Otto, M., Teipel, S. J., Zinkowski, R., Blennow, K., DeBernardis, J., Kerkman, D., Schröder, J., Schönknecht, P., Cepek, L., et al. (2006) · Neurobiology of Aging

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 70

Characterizing the Clinical Features and Atrophy Patterns of MAPT -Related Frontotemporal Dementia With Disease Progression Modeling

Young, A. L., Bocchetta, M., Russell, L. L., Convery, R. S., Peakman, G., Todd, E., Cash, D. M., Greaves, C. V., van Swieten, J., Jiskoot, L., et al. (2021) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 62

Biomarkers for diseases with TDP-43 pathology

Steinacker, P., Barschke, P., & Otto, M. (2019) · Molecular and Cellular Neuroscience

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 57

Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: a German–Austrian retrospective multicenter study in patients with a clinically-isolated syndrome

Huss, A. M., Halbgebauer, S., Öckl, P., Trebst, C., Spreer, A., Borisow, N., Harrer, A., Brecht, I., Balint, B., Stich, O., et al. (2016) · Journal of Neurology

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 54

Predicting primary progressive aphasias with support vector machine approaches in structural MRI data

Bisenius, S., Mueller, K., Diehl-Schmid, J., Fassbender, K., Grimmer, T., Jessen, F., Kassubek, J., Kornhuber, J., Landwehrmeyer, B., Ludolph, A., et al. (2017) · NeuroImage: Clinical

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 51

Different CSF protein profiles in amyotrophic lateral sclerosis and frontotemporal dementia with C9orf72 hexanucleotide repeat expansion

Barschke, P., Oeckl, P., Steinacker, P., Al Shweiki, M. R., Weishaupt, J. H., Landwehrmeyer, G. B., Anderl-Straub, S., Weydt, P., Diehl-Schmid, J., Danek, A., et al. (2020) · Journal of Neurology, Neurosurgery & Psychiatry

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 45

Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia

Sogorb-Esteve, A., Nilsson, J., Swift, I. J., Heller, C., Bocchetta, M., Russell, L. L., Peakman, G., Convery, R. S., van Swieten, J. C., Seelaar, H., et al. (2022) · Alzheimer's Research & Therapy

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 39

Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration

Tavares, T. P., Mitchell, D. G. V., Coleman, K. K., Coleman, B. L., Shoesmith, C. L., Butler, C. R., Santana, I., Danek, A., Gerhard, A., de Mendonca, A., et al. (2020) · Journal of Neurology, Neurosurgery & Psychiatry

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 39

Incremental value of serum neurofilament light chain and glial fibrillary acidic protein as blood-based biomarkers for predicting functional outcome in severe acute ischemic stroke

Vollmuth, C., Fiessler, C., Montellano, F. A., Kollikowski, A. M., Essig, F., Oeckl, P., Barba, L., Steinacker, P., Schulz, C., Ungethüm, K., et al. (2024) · European Stroke Journal

Acute Ischemic Stroke ManagementStroke Rehabilitation and Recovery

Cited by 38

Progranulin as a candidate biomarker for therapeutic trial in patients with ALS and FTLD

Feneberg, E., Steinacker, P., Volk, A. E., Weishaupt, J. H., Wollmer, M. A., Boxer, A., Tumani, H., Ludolph, A. C., & Otto, M. (2016) · Journal of Neural Transmission

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 36

Education modulates brain maintenance in presymptomatic frontotemporal dementia

Gazzina, S., Grassi, M., Premi, E., Cosseddu, M., Alberici, A., Archetti, S., Gasparotti, R., Van Swieten, J., Galimberti, D., Sanchez-Valle, R., et al. (2019) · Journal of Neurology, Neurosurgery & Psychiatry

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 33

Oligoclonal bands and kappa free light chains: Competing parameters or complementary biomarkers?

Konen, F. F., Wurster, U., Schwenkenbecher, P., Gerritzen, A., Groß, C. C., Eichhorn, P., Harrer, A., Isenmann, S., Lewczuk, P., Lewerenz, J., et al. (2025) · Autoimmunity Reviews

Multiple Sclerosis Research StudiesPeripheral Neuropathies and Disorders

Cited by 31

Sequence of proteome profiles in preclinical and symptomatic Alzheimer's disease

Li, X., Tsolis, K. C., Koper, M. J., Ronisz, A., Ospitalieri, S., von Arnim, C. A. F., Vandenberghe, R., Tousseyn, T., Scheuerle, A., Economou, A., et al. (2021) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 27