Vogelstein, Bert

The Antisense Transcriptomes of Human Cells

He, Y., Vogelstein, B., Velculescu, V. E., Papadopoulos, N., & Kinzler, K. W. (2008) · Science

Cancer-related molecular mechanisms researchGenomics and Chromatin Dynamics

Cited by 531

Activating Mutations of the Noonan Syndrome-Associated SHP2/PTPN11 Gene in Human Solid Tumors and Adult Acute Myelogenous Leukemia

Bentires-Alj, M., Paez, J. G., David, F. S., Keilhack, H., Halmos, B., Naoki, K., Maris, J. M., Richardson, A., Bardelli, A., Sugarbaker, D. J., et al. (2004) · Cancer Research

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 509

ATM Mutations in Patients with Hereditary Pancreatic Cancer

Roberts, N. J., Jiao, Y., Yu, J., Kopelovich, L., Petersen, G. M., Bondy, M. L., Gallinger, S., Schwartz, A. G., Syngal, S., Cote, M. L., et al. (2012) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchGenetic factors in colorectal cancer

Cited by 491

A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts

Springer, S., Wang, Y., Dal Molin, M., Masica, D. L., Jiao, Y., Kinde, I., Blackford, A., Raman, S. P., Wolfgang, C. L., Tomita, T., et al. (2015) · Gastroenterology

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 477

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

Reitman, Z. J., Jin, G., Karoly, E. D., Spasojevic, I., Yang, J., Kinzler, K. W., He, Y., Bigner, D. D., Vogelstein, B., & Yan, H. (2011) · Proceedings of the National Academy of Sciences

Glioma Diagnosis and TreatmentCancer, Hypoxia, and Metabolism

Cited by 449

Epitope Landscape in Breast and Colorectal Cancer

Segal, N. H., Parsons, D. W., Peggs, K. S., Velculescu, V., Kinzler, K. W., Vogelstein, B., & Allison, J. P. (2008) · Cancer Research

vaccines and immunoinformatics approachesImmunotherapy and Immune Responses

Cited by 416

Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer

Makohon-Moore, A. P., Zhang, M., Reiter, J. G., Bozic, I., Allen, B., Kundu, D., Chatterjee, K., Wong, F., Jiao, Y., Kohutek, Z. A., et al. (2017) · Nature Genetics

Cancer Genomics and DiagnosticsPancreatic and Hepatic Oncology Research

Cited by 403

Intratumoral injection of Clostridium novyi -NT spores induces antitumor responses

Roberts, N. J., Zhang, L., Janku, F., Collins, A., Bai, R.-Y., Staedtke, V., Rusk, A. W., Tung, D., Miller, M., Roix, J., et al. (2014) · Science Translational Medicine

Bacterial Cancer TherapyClostridium difficile and Clostridium perfringens research

Cited by 400

Disruption of HAUSP gene stabilizes p53.

Cummins, J. M., Rago, C., Kohli, M., Kinzler, K. W., Lengauer, C., & Vogelstein, B. (2004) · Nature

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 379

SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer

Blackford, A., Serrano, O. K., Wolfgang, C. L., Parmigiani, G., Jones, S., Zhang, X., Parsons, D. W., Lin, J. C.-H., Leary, R. J., Eshleman, J. R., et al. (2009) · Clinical Cancer Research

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 371

Targeting a neoantigen derived from a common TP53 mutation

Hsiue, E. H.-C., Wright, K. M., Douglass, J., Hwang, M. S., Mog, B. J., Pearlman, A. H., Paul, S., DiNapoli, S. R., Konig, M. F., Wang, Q., et al. (2021) · Science

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 367

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer

Roberts, N. J., Norris, A. L., Petersen, G. M., Bondy, M. L., Brand, R., Gallinger, S., Kurtz, R. C., Olson, S. H., Rustgi, A. K., Schwartz, A. G., et al. (2016) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchGenetic factors in colorectal cancer

Cited by 361

Sensitive digital quantification of DNA methylation in clinical samples

Li, M., Chen, W.-D., Papadopoulos, N., Goodman, S. N., Bjerregaard, N. C., Laurberg, S., Levin, B., Juhl, H., Arber, N., Moinova, H., et al. (2009) · Nature Biotechnology

Epigenetics and DNA MethylationCancer Genomics and Diagnostics

Cited by 341

Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers.

Kinde, I., Bettegowda, C., Wang, Y., Wu, J., Agrawal, N., Shih, I.-M., Kurman, R., Dao, F., Levine, D. A., Giuntoli, R., et al. (2013) · Science Translational Medicine

Cancer Genomics and DiagnosticsCervical Cancer and HPV Research

Cited by 327

Next-Generation Stool DNA Test Accurately Detects Colorectal Cancer and Large Adenomas

Ahlquist, D. A., Zou, H., Domanico, M., Mahoney, D. W., Yab, T. C., Taylor, W. R., Butz, M. L., Thibodeau, S. N., Rabeneck, L., Paszat, L. F., et al. (2012) · Gastroenterology

Colorectal Cancer Screening and DetectionGenetic factors in colorectal cancer

Cited by 315

Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer

Hao, Y., Samuels, Y., Li, Q., Krokowski, D., Guan, B.-J., Wang, C., Jin, Z., Dong, B., Cao, B., Feng, X., et al. (2016) · Nature Communications

Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer

Cited by 290

Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome

Staedtke, V., Bai, R.-Y., Kim, K., Darvas, M., Davila, M. L., Riggins, G. J., Rothman, P. B., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., et al. (2018) · Nature

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 277

BEAMing up for detection and quantification of rare sequence variants

Li, M., Diehl, F., Dressman, D., Vogelstein, B., & Kinzler, K. W. (2006) · Nature Methods

Advanced biosensing and bioanalysis techniquesMolecular Biology Techniques and Applications

Cited by 261

TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine

Kinde, I., Munari, E., Faraj, S. F., Hruban, R. H., Schoenberg, M., Bivalacqua, T., Allaf, M., Springer, S., Wang, Y., Diaz, L. A., et al. (2013) · Cancer Research

Bladder and Urothelial Cancer TreatmentsUrinary and Genital Oncology Studies

Cited by 253

Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing

Hoang, M. L., Kinde, I., Tomasetti, C., McMahon, K. W., Rosenquist, T. A., Grollman, A. P., Kinzler, K. W., Vogelstein, B., & Papadopoulos, N. (2016) · Proceedings of the National Academy of Sciences

Cancer Genomics and DiagnosticsGenomics and Phylogenetic Studies

Cited by 224

A multimodality test to guide the management of patients with a pancreatic cyst

Springer, S., Masica, D. L., Dal Molin, M., Douville, C., Thoburn, C. J., Afsari, B., Li, L., Cohen, J. D., Thompson, E., Allen, P. J., et al. (2019) · Science Translational Medicine

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 217

Characterization of MAD2B and Other Mitotic Spindle Checkpoint Genes

Cahill, D. P., da Costa, L. T., Carson-Walter, E. B., Kinzler, K. W., Vogelstein, B., & Lengauer, C. (1999) · Genomics

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

Cited by 212

X-Linked Inhibitor of Apoptosis Protein (XIAP) Is a Nonredundant Modulator of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)- Mediated Apoptosis in Human Cancer Cells

Cummins, J. M., Kohli, M., Rago, C., Kinzler, K. W., Vogelstein, B., & Bunz, F. (2004) · Cancer Research

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 200

Utility of CT Radiomics Features in Differentiation of Pancreatic Ductal Adenocarcinoma From Normal Pancreatic Tissue.

Chu, L. C., Park, S., Kawamoto, S., Fouladi, D. F., Shayesteh, S., Zinreich, E. S., Graves, J. S., Horton, K. M., Hruban, R. H., Yuille, A. L., et al. (2019) · American Journal of Roentgenology

Radiomics and Machine Learning in Medical ImagingPancreatic and Hepatic Oncology Research

Cited by 193