Herzig, Stephan

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

Herzig, S., Long, F., Jhala, U. S., Hedrick, S., Quinn, R., Bauer, A., Rudolph, D., Schutz, G., Yoon, C., Puigserver, P., et al. (2001) · Nature

Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors

Cited by 1,440

TRB3: A tribbles Homolog That Inhibits Akt/PKB Activation by Insulin in Liver

Du, K., Herzig, S., Kulkarni, R. N., & Montminy, M. (2003) · Science

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 842

PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3

Koo, S.-H., Satoh, H., Herzig, S., Lee, C.-H., Hedrick, S., Kulkarni, R., Evans, R. M., Olefsky, J., & Montminy, M. (2004) · Nature Medicine

Peroxisome Proliferator-Activated ReceptorsMetabolism, Diabetes, and Cancer

Cited by 550

Glucocorticoids, metabolism and metabolic diseases

Vegiopoulos, A., & Herzig, S. (2007) · Molecular and Cellular Endocrinology

Estrogen and related hormone effectsAdipokines, Inflammation, and Metabolic Diseases

Cited by 535

The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling

Zhang, Q., Delessa, C. T., Augustin, R., Bakhti, M., Colldén, G., Drucker, D. J., Feuchtinger, A., Caceres, C. G., Grandl, G., Harger, A., et al. (2021) · Cell Metabolism

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 322

Selective enrichment of newly synthesized proteins for quantitative secretome analysis

Eichelbaum, K., Winter, M., Diaz, M. B., Herzig, S., & Krijgsveld, J. (2012) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsClick Chemistry and Applications

Cited by 248

A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution

Maida, A., Zota, A., Sjøberg, K. A., Schumacher, J., Sijmonsma, T. P., Pfenninger, A., Christensen, M. M., Gantert, T., Fuhrmeister, J., Rothermel, U., et al. (2016) · Journal of Clinical Investigation

Fibroblast Growth Factor ResearchDiet, Metabolism, and Disease

Cited by 170

Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication

Loft, A., Alfaro, A. J., Schmidt, S. F., Pedersen, F. B., Terkelsen, M. K., Puglia, M., Chow, K. K., Feuchtinger, A., Troullinaki, M., Maida, A., et al. (2021) · Cell Metabolism

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 129

Functional Inactivation of the Genome-Wide Association Study Obesity Gene Neuronal Growth Regulator 1 in Mice Causes a Body Mass Phenotype

Lee, A. W. S., Hengstler, H., Schwald, K., Berriel-Diaz, M., Loreth, D., Kirsch, M., Kretz, O., Haas, C. A., de Angelis, M. H., Herzig, S., et al. (2012) · PLoS ONE

Regulation of Appetite and ObesityGenetic Associations and Epidemiology

Cited by 84

A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis

Loft, A., Schmidt, S. F., Caratti, G., Stifel, U., Havelund, J., Sekar, R., Kwon, Y., Sulaj, A., Chow, K. K., Alfaro, A. J., et al. (2022) · Cell Metabolism

Dietary Effects on HealthPeroxisome Proliferator-Activated Receptors

Cited by 76

Jak-TGFβ cross-talk links transient adipose tissue inflammation to beige adipogenesis

Babaei, R., Schuster, M., Meln, I., Lerch, S., Ghandour, R. A., Pisani, D. F., Bayindir-Buchhalter, I., Marx, J., Wu, S., Schoiswohl, G., et al. (2018) · Science Signaling

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 53

Molecular regulation of urea cycle function by the liver glucocorticoid receptor

Okun, J. G., Conway, S., Schmidt, K. V., Schumacher, J., Wang, X., de Guia, R., Zota, A., Klement, J., Seibert, O., Peters, A., et al. (2015) · Molecular Metabolism

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 53

PPP2R5C couples hepatic glucose and lipid homeostasis

Cheng, Y.-S., Seibert, O., Klöting, N., Dietrich, A., Straßburger, K., Fernández-Veledo, S., Vendrell, J. J., Zorzano, A., Blüher, M., Herzig, S., et al. (2015) · PLoS Genetics

Metabolism, Diabetes, and CancerDiet, Metabolism, and Disease

Cited by 43

Virtual reality-empowered deep-learning analysis of brain cells

Kaltenecker, D., Al-Maskari, R., Negwer, M., Hoeher, L., Kofler, F., Zhao, S., Todorov, M., Rong, Z., Paetzold, J. C., Wiestler, B., et al. (2024) · Nature Methods

Cell Image Analysis TechniquesSingle-cell and spatial transcriptomics

Cited by 38

Control of diabetic hyperglycaemia and insulin resistance through TSC22D4

Ekim Üstünel, B., Friedrich, K., Maida, A., Wang, X., Krones-Herzig, A., Seibert, O., Sommerfeld, A., Jones, A., Sijmonsma, T. P., Sticht, C., et al. (2016) · Nature Communications

Adipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer

Cited by 36

Obesity and cancer—extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseases

Pellegata, N. S., Berriel Diaz, M., Rohm, M., & Herzig, S. (2022) · Cancer and Metastasis Reviews

Cancer Risks and FactorsCancer, Lipids, and Metabolism

Cited by 33

Chronic intermittent fasting impairs β cell maturation and function in adolescent mice

Matta, L., Weber, P., Erener, S., Walth-Hummel, A., Hass, D., Bühler, L. K., Klepac, K., Szendroedi, J., Guerra, J., Rohm, M., et al. (2025) · Cell Reports

Dietary Effects on HealthPancreatic function and diabetes

Cited by 22

Fasting‐sensitive SUMO‐switch on Prox1 controls hepatic cholesterol metabolism

Alfaro, A. J., Dittner, C., Becker, J., Loft, A., Mhamane, A., Maida, A., Georgiadi, A., Tsokanos, F., Klepac, K., Molocea, C., et al. (2023) · The EMBO Reports

Cholesterol and Lipid MetabolismLiver Disease Diagnosis and Treatment

Cited by 14

A deep-learning framework reveals whole-body perturbations at cell level

Kaltenecker, D., Horvath, I., Al-Maskari, R., Chen, Y., Kolabas, Z. I., Hoeher, L., Todorov, M., Minde, D.-P., Kapoor, S., Turhan, S. G., et al. (2026) · Nature

Cell Image Analysis TechniquesSingle-cell and spatial transcriptomics

Cited by 5