Fliers, Eric

Circadian disruption and SCN control of energy metabolism

Kalsbeek, A., Scheer, F. A., Perreau-Lenz, S., La Fleur, S. E., Yi, C.-X., Fliers, E., & Buijs, R. M. (2011) · FEBS Letters

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 133

MECHANISMS IN ENDOCRINOLOGY: Beyond the fixed setpoint of the hypothalamus–pituitary–thyroid axis

Fliers, E., Kalsbeek, A., & Boelen, A. (2014) · European Journal of Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 124

The influence of thyroid function on the coagulation system and its clinical consequences

Elbers, L. P. B., Fliers, E., & Cannegieter, S. C. (2018) · Journal of Thrombosis and Haemostasis

Thyroid Disorders and TreatmentsBlood Coagulation and Thrombosis Mechanisms

Cited by 123

White Adipose Tissue: Getting Nervous

Fliers, E., Kreier, F., Voshol, P. J., Havekes, L. M., Sauerwein, H. P., Kalsbeek, A., Buijs, R. M., & Romijn, J. A. (2003) · Journal of Neuroendocrinology

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 114

Extrahypothalamic vasopressin and oxytocin in the human brain; presence of vasopressin cells in the bed nucleus of the stria terminalis

Fliers, E., Guldenaar, S. E. F., Wal, N. V. D., & Swaab, D. F. (1986) · Brain Research

Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology

Cited by 114

Polymorphisms in the brain‐specific thyroid hormone transporter OATP1C1 are associated with fatigue and depression in hypothyroid patients

Van Der Deure, W. M., Appelhof, B. C., Peeters, R. P., Wiersinga, W. M., Wekking, E. M., Huyser, J., Schene, A. H., Tijssen, J. G. P., Hoogendijk, W. J. G., Visser, T. J., et al. (2008) · Clinical Endocrinology

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 97

Mutations in TBL1X Are Associated With Central Hypothyroidism

Heinen, C. A., Losekoot, M., Sun, Y., Watson, P. J., Fairall, L., Joustra, S. D., Zwaveling-Soonawala, N., Oostdijk, W., van den Akker, E. L. T., Alders, M., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGenomics and Rare Diseases

Cited by 92

IGSF1 Deficiency: Lessons From an Extensive Case Series and Recommendations for Clinical Management

Joustra, S. D., Heinen, C. A., Schoenmakers, N., Bonomi, M., Ballieux, B. E. P. B., Turgeon, M.-O., Bernard, D. J., Fliers, E., van Trotsenburg, A. S. P., Losekoot, M., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Immunodeficiency and Autoimmune DisordersThyroid Disorders and Treatments

Cited by 91

Polymorphisms in type 2 deiodinase are not associated with well-being, neurocognitive functioning, and preference for combined thyroxine/3,5,3′-triiodothyronine therapy

Appelhof, B. C., Peeters, R. P., Wiersinga, W. M., Visser, T. J., Wekking, E. M., Huyser, J., Schene, A. H., Tijssen, J. G. P., Hoogendijk, W. J. G., & Fliers, E. (2005) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 91

A Novel Role for the Thyroid Hormone-Activating Enzyme Type 2 Deiodinase in the Inflammatory Response of Macrophages

Kwakkel, J., Surovtseva, O. V., de Vries, E. M., Stap, J., Fliers, E., & Boelen, A. (2014) · Endocrinology

Thyroid Disorders and TreatmentsImmune Response and Inflammation

Cited by 88

Changes in the central component of the hypothalamus-pituitary-thyroid axis in a rabbit model of prolonged critical illness

Mebis, L., Debaveye, Y., Ellger, B., Derde, S., Ververs, E.-J., Langouche, L., Darras, V. M., Fliers, E., Visser, T. J., & Van den Berghe, G. (2009) · Critical Care

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 82

Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document

Jonklaas, J., Bianco, A. C., Cappola, A. R., Celi, F. S., Fliers, E., Heuer, H., McAninch, E. A., Moeller, L. C., Nygaard, B., Sawka, A. M., et al. (2021) · European Thyroid Journal

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 78

Treatment of Amiodarone-Induced Thyrotoxicosis Type 2: A Randomized Clinical Trial

Eskes, S. A., Endert, E., Fliers, E., Geskus, R. B., Dullaart, R. P. F., Links, T. P., & Wiersinga, W. M. (2012) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 78

A specific mutation in TBL1XR1 causes Pierpont syndrome

Heinen, C. A., Jongejan, A., Watson, P. J., Redeker, B., Boelen, A., Boudzovitch-Surovtseva, O., Forzano, F., Hordijk, R., Kelley, R., Olney, A. H., et al. (2016) · Journal of Medical Genetics

Genomics and Rare DiseasesGenetics and Neurodevelopmental Disorders

Cited by 73

Distribution of thyrotropin-releasing hormone (TRH)-containing cells and fibers in the human hypothalamus

Fliers, E., Noppen, N. W. A. M., Wiersinga, W. M., Visser, T. J., & Swaab, D. F. (1994) · Journal of Comparative Neurology

Hypothalamic control of reproductive hormonesNeuropeptides and Animal Physiology

Cited by 73

Type 3 Deiodinase Is Highly Expressed in Infiltrating Neutrophilic Granulocytes in Response to Acute Bacterial Infection

Boelen, A., Boorsma, J., Kwakkel, J., Wieland, C. W., Renckens, R., Visser, T. J., Fliers, E., & Wiersinga, W. M. (2008) · Thyroid

Thyroid Disorders and TreatmentsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 70

The hypothalamic-pituitary-thyroid axis in critical illness

Fliers, E., Alkemade, A., & Wiersinga, W. M. (2001) · Best Practice & Research Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 69

Resistance to Thyroid Hormone Alpha in an 18-Month-Old Girl: Clinical, Therapeutic, and Molecular Characteristics

van Gucht, A. L. M., Meima, M. E., Zwaveling-Soonawala, N., Visser, W. E., Fliers, E., Wennink, J. M. B., Henny, C., Visser, T. J., Peeters, R. P., & van Trotsenburg, A. S. P. (2016) · Thyroid

Thyroid Disorders and TreatmentsGenomics and Rare Diseases

Cited by 67

Pilot study on the assessment of the setpoint of the hypothalamus-pituitary-thyroid axis in healthy volunteers

Benhadi, N., Fliers, E., Visser, T. J., Reitsma, J. B., & Wiersinga, W. M. (2010) · European Journal of Endocrinology

Thyroid Disorders and TreatmentsClinical Laboratory Practices and Quality Control

Cited by 66

Chronic local inflammation in mice results in decreased TRH and type 3 deiodinase mRNA expression in the hypothalamic paraventricular nucleus independently of diminished food intake

Boelen, A., Kwakkel, J., Wiersinga, W. M., & Fliers, E. (2006) · Journal of Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 64

Impaired Bacterial Clearance in Type 3 Deiodinase-Deficient Mice Infected with Streptococcus pneumoniae

Boelen, A., Kwakkel, J., Wieland, C. W., St. Germain, D. L., Fliers, E., & Hernandez, A. (2009) · Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 63

Regulation of Intracellular Triiodothyronine Is Essential for Optimal Macrophage Function

van der Spek, A. H., Surovtseva, O. V., Jim, K. K., van Oudenaren, A., Brouwer, M. C., Vandenbroucke-Grauls, C. M. J. E., Leenen, P. J. M., van de Beek, D., Hernandez, A., Fliers, E., et al. (2018) · Endocrinology

Thyroid Disorders and TreatmentsImmune cells in cancer

Cited by 62

Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner

Milanova, I. V., Kalsbeek, M. J. T., Wang, X.-L., Korpel, N. L., Stenvers, D. J., Wolff, S. E. C., de Goede, P., Heijboer, A. C., Fliers, E., la Fleur, S. E., et al. (2019) · Frontiers in Endocrinology

Neuroinflammation and Neurodegeneration MechanismsCircadian rhythm and melatonin

Cited by 53

Thr92Ala polymorphism in the type 2 deiodinase is not associated with T4 dose in athyroid patients or patients with Hashimoto thyroiditis

Heemstra, K. A., Hoftijzer, H. C., Van Der Deure, W. M., Peeters, R. P., Fliers, E., Appelhof, B. C., Wiersinga, W. M., Corssmit, E. P. M., Visser, T. J., & Smit, J. W. A. (2009) · Clinical Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 51