Glimcher, Laurie H.

Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Özcan, U., Cao, Q., Yilmaz, E., Lee, A.-H., Iwakoshi, N. N., Özdelen, E., Tuncman, G., Görgün, C., Glimcher, L. H., & Hotamisligil, G. S. (2004) · Science

Endoplasmic Reticulum Stress and DiseaseAdipokines, Inflammation, and Metabolic Diseases

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A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, C. G., & Glimcher, L. H. (2000) · Cell

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 3,589

Distinct Effects of T-bet in T H 1 Lineage Commitment and IFN-γ Production in CD4 and CD8 T Cells

Szabo, S. J., Sullivan, B. M., Stemmann, C., Satoskar, A. R., Sleckman, B. P., & Glimcher, L. H. (2002) · Science

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 1,172

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

Martinon, F., Chen, X., Lee, A.-H., & Glimcher, L. H. (2010) · Nature Immunology

Immune Response and InflammationEndoplasmic Reticulum Stress and Disease

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ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis

Cubillos-Ruiz, J. R., Silberman, P. C., Rutkowski, M. R., Chopra, S., Perales-Puchalt, A., Song, M., Zhang, S., Bettigole, S. E., Gupta, D., Holcomb, K., et al. (2015) · Cell

Immunotherapy and Immune ResponsesEndoplasmic Reticulum Stress and Disease

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Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

Iwakoshi, N. N., Lee, A.-H., Vallabhajosyula, P., Otipoby, K. L., Rajewsky, K., & Glimcher, L. H. (2003) · Nature Immunology

Endoplasmic Reticulum Stress and DiseaseT-cell and B-cell Immunology

Cited by 880

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

Garrett, W. S., Gallini, C. A., Yatsunenko, T., Michaud, M., DuBois, A., Delaney, M. L., Punit, S., Karlsson, M., Bry, L., Glickman, J. N., et al. (2010) · Cell Host & Microbe

Gut microbiota and healthInflammatory Bowel Disease

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The transcription factor NF-ATc is essential for cardiac valve formation

Ranger, A. M., Grusby, M. J., Hodge, M. R., Gravallese, E. M., de la Brousse, F. C., Hoey, T., Mickanin, C., Baldwin, H. S., & Glimcher, L. H. (1998) · Nature

Congenital heart defects researchSignaling Pathways in Disease

Cited by 586

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

Hetz, C., Thielen, P., Matus, S., Nassif, M., Court, F., Kiffin, R., Martinez, G., Cuervo, A. M., Brown, R. H., & Glimcher, L. H. (2009) · Genes & Development

Amyotrophic Lateral Sclerosis ResearchEndoplasmic Reticulum Stress and Disease

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T Helper Cell Fate Specified by Kinase-Mediated Interaction of T-bet with GATA-3

Hwang, E. S., Szabo, S. J., Schwartzberg, P. L., & Glimcher, L. H. (2005) · Science

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

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T-bet: a bridge between innate and adaptive immunity

Lazarevic, V., Glimcher, L. H., & Lord, G. M. (2013) · Nature Reviews Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

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An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease

Zhang, S., Ermann, J., Succi, M. D., Zhou, A., Hamilton, M. J., Cao, B., Korzenik, J. R., Glickman, J. N., Vemula, P. K., Glimcher, L. H., et al. (2015) · Science Translational Medicine

Advanced Drug Delivery SystemsInflammatory Bowel Disease

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Transcriptional regulation of Th1/Th2 polarization

Rengarajan, J., Szabo, S. J., & Glimcher, L. H. (2000) · Immunology Today

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

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NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells

Horsley, V., Aliprantis, A. O., Polak, L., Glimcher, L. H., & Fuchs, E. (2008) · Cell

Hair Growth and DisordersSignaling Pathways in Disease

Cited by 424

IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

Song, M., Sandoval, T. A., Chae, C.-S., Chopra, S., Tan, C., Rutkowski, M. R., Raundhal, M., Chaurio, R. A., Payne, K. K., Konrad, C., et al. (2018) · Nature

Endoplasmic Reticulum Stress and DiseaseCancer Immunotherapy and Biomarkers

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Signaling pathways in Th2 development

Mowen, K. A., & Glimcher, L. H. (2004) · Immunological Reviews

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

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XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

Todd, D. J., McHeyzer-Williams, L. J., Kowal, C., Lee, A.-H., Volpe, B. T., Diamond, B., McHeyzer-Williams, M. G., & Glimcher, L. H. (2009) · Journal of Experimental Medicine

Endoplasmic Reticulum Stress and DiseaseT-cell and B-cell Immunology

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Regulation of Memory Formation by the Transcription Factor XBP1

Martínez, G., Vidal, R. L., Mardones, P., Serrano, F. G., Ardiles, A. O., Wirth, C., Valdés, P., Thielen, P., Schneider, B. L., Kerr, B., et al. (2016) · Cell Reports

Memory and Neural MechanismsEndoplasmic Reticulum Stress and Disease

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Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3

Jones, D. C., Schweitzer, M. N., Wein, M., Sigrist, K., Takagi, T., Ishii, S., & Glimcher, L. H. (2010) · Proceedings of the National Academy of Sciences

Bone Metabolism and DiseasesOsteoarthritis Treatment and Mechanisms

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