Rappsilber, Juri

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

Rappsilber, J., Mann, M., & Ishihama, Y. (2007) · Nature Protocols

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 4,641

Exponentially Modified Protein Abundance Index (emPAI) for Estimation of Absolute Protein Amount in Proteomics by the Number of Sequenced Peptides per Protein

Ishihama, Y., Oda, Y., Tabata, T., Sato, T., Nagasu, T., Rappsilber, J., & Mann, M. (2005) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 2,055

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

Williams, K., Christensen, J., Pedersen, M. T., Johansen, J. V., Cloos, P. A. C., Rappsilber, J., & Helin, K. (2011) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,021

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

Lyst, M. J., Ekiert, R., Ebert, D. H., Merusi, C., Nowak, J., Selfridge, J., Guy, J., Kastan, N. R., Robinson, N. D., de Lima Alves, F., et al. (2013) · Nature Neuroscience

Genetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation

Cited by 410

The IntAct database: efficient access to fine-grained molecular interaction data

del Toro, N., Shrivastava, A., Ragueneau, E., Meldal, B., Combe, C., Barrera, E., Perfetto, L., How, K., Ratan, P., Shirodkar, G., et al. (2022) · Nucleic Acids Research

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 405

xiNET: cross-link network maps with residue resolution

Combe, C. W., Fischer, L., & Rappsilber, J. (2015) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 296

In-cell architecture of an actively transcribing-translating expressome

O’Reilly, F. J., Xue, L., Graziadei, A., Sinn, L., Lenz, S., Tegunov, D., Blötz, C., Singh, N., Hagen, W. J. H., Cramer, P., et al. (2020) · Science

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 284

Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A‐ARF locus

Dietrich, N., Bracken, A. P., Trinh, E., Schjerling, C. K., Koseki, H., Rappsilber, J., Helin, K., & Hansen, K. H. (2007) · The EMBO Journal

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 187

Visualizing translation dynamics at atomic detail inside a bacterial cell

Xue, L., Lenz, S., Zimmermann-Kogadeeva, M., Tegunov, D., Cramer, P., Bork, P., Rappsilber, J., & Mahamid, J. (2022) · Nature

RNA and protein synthesis mechanismsAdvanced Electron Microscopy Techniques and Applications

Cited by 184

Tissue-specific control of brain-enriched miR-7 biogenesis

Choudhury, N. R., de Lima Alves, F., de Andrés-Aguayo, L., Graf, T., Cáceres, J. F., Rappsilber, J., & Michlewski, G. (2013) · Genes & Development

MicroRNA in disease regulationRNA Research and Splicing

Cited by 158

Reliable identification of protein-protein interactions by crosslinking mass spectrometry

Lenz, S., Sinn, L. R., O’Reilly, F. J., Fischer, L., Wegner, F., & Rappsilber, J. (2021) · Nature Communications

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 157

Protein complexes in cells by AI-assisted structural proteomics

O‘Reilly, F. J., Graziadei, A., Forbrig, C., Bremenkamp, R., Charles, K., Lenz, S., Elfmann, C., Fischer, L., Stülke, J., & Rappsilber, J. (2022) · Molecular Systems Biology

Protein Structure and DynamicsAdvanced Proteomics Techniques and Applications

Cited by 147

The structure of human thyroglobulin

Coscia, F., Taler-Verčič, A., Chang, V. T., Sinn, L., O’Reilly, F. J., Izoré, T., Renko, M., Berger, I., Rappsilber, J., Turk, D., et al. (2020) · Nature

Thyroid Disorders and TreatmentsEnzyme Structure and Function

Cited by 147

DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network

Carraro, M., Hendriks, I. A., Hammond, C. M., Solis, V., Völker-Albert, M., Elsborg, J. D., Weisser, M. B., Spanos, C., Montoya, G., Rappsilber, J., et al. (2022) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 62

Prdm5 Regulates Collagen Gene Transcription by Association with RNA Polymerase II in Developing Bone

Galli, G. G., Honnens de Lichtenberg, K., Carrara, M., Hans, W., Wuelling, M., Mentz, B., Multhaupt, H. A., Fog, C. K., Jensen, K. T., Rappsilber, J., et al. (2012) · PLoS Genetics

Bone Metabolism and DiseasesBone and Dental Protein Studies

Cited by 61

PLK1-mediated phosphorylation cascade activates Mis18 complex to ensure centromere inheritance

Parashara, P., Medina-Pritchard, B., Abad, M. A., Sotelo-Parrilla, P., Thamkachy, R., Grundei, D., Zou, J., Spanos, C., Kumar, C. N., Basquin, C., et al. (2024) · Science

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 36

Substrate specificity of the TRAMP nuclear surveillance complexes

Delan-Forino, C., Spanos, C., Rappsilber, J., & Tollervey, D. (2020) · Nature Communications

RNA Research and SplicingNuclear Structure and Function

Cited by 36

PLK1-Mediated Phosphorylation Cascade Activates the Mis18 Complex to Ensure Centromere Inheritance

Parashara, P., Medina-Pritchard, B., Abad, M. A., Sotelo-Parrilla, P., Thamkachy, R., Grundei, D., Zou, J., Das, V., Yan, Z., Kelly, D. A., et al. (2024) · Science

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 36

Molecular basis of mRNA delivery to the bacterial ribosome

Webster, M. W., Chauvier, A., Rahil, H., Graziadei, A., Charles, K., Miropolskaya, N., Takacs, M., Saint-André, C., Rappsilber, J., Walter, N. G., et al. (2024) · Science

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 32

Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition

Syred, H. M., Welburn, J., Rappsilber, J., & Ohkura, H. (2013) · Molecular & Cellular Proteomics

Microtubule and mitosis dynamicsBiotin and Related Studies

Cited by 25

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit

Milligan, L., Sayou, C., Tuck, A., Auchynnikava, T., Reid, J. E., Alexander, R., Alves, F. D. L., Allshire, R., Spanos, C., Rappsilber, J., et al. (2017) · eLife

RNA Research and SplicingGenomics and Chromatin Dynamics

Cited by 23

Mapping the invisible chromatin transactions of prophase chromosome remodeling

Samejima, I., Spanos, C., Samejima, K., Rappsilber, J., Kustatscher, G., & Earnshaw, W. C. (2022) · Molecular Cell

Genomics and Chromatin DynamicsMicrotubule and mitosis dynamics

Cited by 21

Mapping the invisible chromatin transactions of prophase chromosome remodelling

Samejima, I., Spanos, C., Samejima, K., Rappsilber, J., Kustatscher, G., & Earnshaw, W. C. (2021) · Molecular Cell

Genomics and Chromatin DynamicsMicrotubule and mitosis dynamics

Cited by 21

Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance

Yaseen, I., White, S. A., Torres-Garcia, S., Spanos, C., Lafos, M., Gaberdiel, E., Yeboah, R., El Karoui, M., Rappsilber, J., Pidoux, A. L., et al. (2022) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 20