Schork, Nicholas J.

Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders

Stein, M. B., Schork, N. J., & Gelernter, J. (2008) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 247

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., et al. (2022) · Biological Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 238

Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach

Ogden, C. A., Rich, M. E., Schork, N. J., Paulus, M. P., Geyer, M. A., Lohr, J. B., Kuczenski, R., & Niculescu, A. B. (2004) · Molecular Psychiatry

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 221

A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa

Wang, K., Zhang, H., Bloss, C. S., Duvvuri, V, Kaye, W., Schork, N. J., Berrettini, W., Hakonarson, H., & the Price Foundation Collaborative Group (2011) · Molecular Psychiatry

Eating Disorders and BehaviorsGenetic Associations and Epidemiology

Cited by 212

Link between gut‐microbiome derived metabolite and shared gene‐effects with hepatic steatosis and fibrosis in NAFLD

Caussy, C., Hsu, C., Lo, M., Liu, A., Bettencourt, R., Ajmera, V. H., Bassirian, S., Hooker, J., Sy, E., Richards, L., et al. (2018) · Hepatology

Liver Disease Diagnosis and TreatmentGut microbiota and health

Cited by 205

Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages

Chow, M. L., Pramparo, T., Winn, M. E., Barnes, C. C., Li, H.-R., Weiss, L., Fan, J.-B., Murray, S., April, C., Belinson, H., et al. (2012) · PLoS Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 202

Convergent functional genomics of genome‐wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms

Le‐Niculescu, H., Patel, S. D., Bhat, M., Kuczenski, R., Faraone, S. V., Tsuang, M. T., McMahon, F. J., Schork, N. J., Nurnberger, J. I., & Niculescu, A. B. (2009) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 201

Discovery and validation of blood biomarkers for suicidality

Le-Niculescu, H., Levey, D. F., Ayalew, M., Palmer, L., Gavrin, L. M., Jain, N., Winiger, E., Bhosrekar, S., Shankar, G., Radel, M., et al. (2013) · Molecular Psychiatry

Suicide and Self-Harm StudiesBipolar Disorder and Treatment

Cited by 193

Sex-specific determinants of increased left ventricular mass in the Tecumseh blood pressure study

Marcus, R., Krause, L., Weder, A. B., Dominguez-Meja, A., Schork, N. J., & Julius, S. (1994) · Circulation

Cardiovascular Function and Risk FactorsBlood Pressure and Hypertension Studies

Cited by 174

Distinct longevity mechanisms across and within species and their association with aging

Tyshkovskiy, A., Ma, S., Shindyapina, A. V., Tikhonov, S., Lee, S.-G., Bozaykut, P., Castro, J. P., Seluanov, A., Schork, N. J., Gorbunova, V., et al. (2023) · Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 162

The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity

Le Stunff, C., Fallin, D., Schork, N. J., & Bougnères, P. (2000) · Nature Genetics

Pancreatic function and diabetesGenetic Associations and Epidemiology

Cited by 154

Singleton deletions throughout the genome increase risk of bipolar disorder

Zhang, D., Cheng, L., Qian, Y., Alliey-Rodriguez, N., Kelsoe, J. R., Greenwood, T., Nievergelt, C., Barrett, T. B., McKinney, R., Schork, N., et al. (2009) · Molecular Psychiatry

Bipolar Disorder and TreatmentGenomic variations and chromosomal abnormalities

Cited by 148

Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia

Torkamani, A., Dean, B., Schork, N. J., & Thomas, E. A. (2010) · Genome Research

Schizophrenia research and treatmentBioinformatics and Genomic Networks

Cited by 134

Accommodating Linkage Disequilibrium in Genetic-Association Analyses via Ridge Regression

Malo, N., Libiger, O., & Schork, N. J. (2008) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 133

Whole-genome mutational burden analysis of three pluripotency induction methods

Bhutani, K., Nazor, K. L., Williams, R., Tran, H., Dai, H., Džakula, Ž., Cho, E. H., Pang, A. W. C., Rao, M., Cao, H., et al. (2016) · Nature Communications

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 129

Gain‐of‐function ADCY5 mutations in familial dyskinesia with facial myokymia

Chen, Y., Friedman, J. R., Chen, D., Chan, G. C. ‐., Bloss, C. S., Hisama, F. M., Topol, S. E., Carson, A. R., Pham, P. H., Bonkowski, E. S., et al. (2014) · Annals of Neurology

Neurological and metabolic disordersDeep Brain Stimulation and Movement Disorders

Cited by 126

Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk

Zhang, L., Rao, F., Zhang, K., Khandrika, S., Das, M., Vaingankar, S. M., Bao, X., Rana, B. K., Smith, D. W., Wessel, J., et al. (2007) · Journal of Clinical Investigation

Genetic Associations and EpidemiologyHeart Rate Variability and Autonomic Control

Cited by 90

Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans

Tang, H., Jorgenson, E., Gadde, M., Kardia, S. L. R., Rao, D. C., Zhu, X., Schork, N. J., Hanis, C. L., & Risch, N. (2006) · Human Genetics

Race, Genetics, and SocietyGenetic Associations and Epidemiology

Cited by 87

Linkage Disequilibrium Analysis of Biallelic DNA Markers, Human Quantitative Trait Loci, and Threshold-Defined Case and Control Subjects

Schork, N. J., Nath, S. K., Fallin, D., & Chakravarti, A. (2000) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 86

Dental Caries and Microbial Acid Production in Twins

Bretz, W. A., Corby, P. M. A., Hart, T. C., Costa, S., Coelho, M. Q., Weyant, R. J., Robinson, M., & Schork, N. J. (2005) · Caries Research

Dental Health and Care UtilizationOral microbiology and periodontitis research

Cited by 82

Generalized Analysis of Molecular Variance

Nievergelt, C. M., Libiger, O., & Schork, N. J. (2007) · PLoS Genetics

Genetic diversity and population structureForensic and Genetic Research

Cited by 80

Cell type discovery and representation in the era of high-content single cell phenotyping

Bakken, T., Cowell, L., Aevermann, B. D., Novotny, M., Hodge, R., Miller, J. A., Lee, A., Chang, I., McCorrison, J., Pulendran, B., et al. (2017) · BMC Bioinformatics

Single-cell and spatial transcriptomicsBiomedical Text Mining and Ontologies

Cited by 55

Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease

Vélez, J. I., Chandrasekharappa, S. C., Henao, E., Martinez, A. F., Harper, U., Jones, M., Solomon, B. D., Lopez, L., Garcia, G., Aguirre-Acevedo, D. C., et al. (2013) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 44

Comparison of Genetic Distance Measures Using Human SNP Genotype Data

Libiger, O., Nievergelt, C. M., & Schork, N. J. (2009) · Human Biology

Forensic and Genetic ResearchGenetic diversity and population structure

Cited by 34