Convergent functional genomics of genome‐wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

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A Neurotrophic Model for Stress-Related Mood Disorders

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Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes

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Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

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Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

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A Common Allele on Chromosome 9 Associated with Coronary Heart Disease

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease

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Serum Brain-Derived Neurotrophic Factor, Depression, and Antidepressant Medications: Meta-Analyses and Implications

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Oligodendrocyte dysfunction in schizophrenia and bipolar disorder.

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Estimating the size of the human interactome

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A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder

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Whole-genome association study of bipolar disorder

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Circadian genes, rhythms and the biology of mood disorders

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Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression

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Distinguishing protein-coding and noncoding genes in the human genome

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The Brain-Derived Neurotrophic Factor Gene Confers Susceptibility to Bipolar Disorder: Evidence from a Family-Based Association Study

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Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions

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Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part III: Bipolar Disorder

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Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus

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Disrupted in Schizophrenia 1 (DISC1): Association with Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder

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Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder

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Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brains

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Dysregulation of the fibroblast growth factor system in major depression

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Toward constructing an endophenotype strategy for bipolar disorders

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Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans

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Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium

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Bipolar I Disorder and Schizophrenia: A 440–Single-Nucleotide Polymorphism Screen of 64 Candidate Genes among Ashkenazi Jewish Case-Parent Trios

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A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2

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Lithium and risk for Alzheimer's disease in elderly patients with bipolar disorder

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Role of GSK3β in behavioral abnormalities induced by serotonin deficiency

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A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior

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Biological rhythm disturbances in mood disorders

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Circadian clock-related polymorphisms in seasonal affective disorder and their relevance to diurnal preference

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Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders

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Evidence for a Relationship Between Genetic Variants at the Brain-Derived Neurotrophic Factor (BDNF) Locus and Major Depression

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Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression

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Suggestive evidence for association of the circadian genes <i>PERIOD3</i> and <i>ARNTL</i> with bipolar disorder

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Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia

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A role for cryptochromesin sleep regulation

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Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease‐associated changes

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A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22

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Molecular Clock Genes in Man and Lower Animals Possible Implications for Circadian Abnormalities in Depression

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Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression

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Endophenotypes in bipolar disorder

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Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23

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Combined Analysis from Eleven Linkage Studies of Bipolar Disorder Provides Strong Evidence of Susceptibility Loci on Chromosomes 6q and 8q

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Operation of the Schizophrenia Susceptibility Gene, Neuregulin 1, Across Traditional Diagnostic Boundaries to Increase Risk for Bipolar Disorder

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Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes

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Downregulation in components of the mitochondrial electron transport chain in the postmortem frontal cortex of subjects with bipolar disorder

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Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression

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Circadian rhythm genetics: from flies to mice to humans

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Prominent synaptic and metabolic abnormalities revealed by proteomic analysis of the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder

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Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach

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Genomewide Linkage Analyses of Bipolar Disorder: A New Sample of 250 Pedigrees from the National Institute of Mental Health Genetics Initiative

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Identifying blood biomarkers for mood disorders using convergent functional genomics

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Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm

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Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach

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Methods for Handling Multiple Testing

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A glycogen synthase kinase 3-β promoter gene single nucleotide polymorphism is associated with age at onset and response to total sleep deprivation in bipolar depression

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Patterns of gene expression in the limbic system of suicides with and without major depression

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Evidence for a Locus on Chromosome 1 That Influences Vulnerability to Alcoholism and Affective Disorder

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Variation at the mu-opioid receptor gene ( <i>OPRM1</i> ) influences attachment behavior in infant primates

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Genome‐wide linkage survey for genetic loci that influence the development of depressive disorders in families with recurrent, early‐onset, major depression

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Temporal relation between sleep and mood in patients with bipolar disorder

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Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia

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The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia

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Suggestive Linkage to Chromosomal Regions 13q31 and 22q12 in Families With Psychotic Bipolar Disorder

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Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders

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Linkage analysis of psychosis in bipolar pedigrees suggests novel putative loci for bipolar disorder and shared susceptibility with schizophrenia

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ALDH1 mRNA: presence in human dopamine neurons and decreases in substantia nigra in Parkinson's disease and in the ventral tegmental area in schizophrenia

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Amyloid-Associated Depression: A Prodromal Depression of Alzheimer Disease?

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Mitochondrially Mediated Plasticity in the Pathophysiology and Treatment of Bipolar Disorder

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A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees

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The Diagnosis, Symptomatology, and Epidemiology of Seasonal Affective Disorder

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Searching for Unique Endophenotypes for Schizophrenia and Bipolar Disorder Within Neural Circuits and Their Molecular Regulatory Mechanisms

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Mouse brain gene expression changes after acute and chronic amphetamine

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PhenoChipping of psychotic disorders: A novel approach for deconstructing and quantitating psychiatric phenotypes

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Proposed endophenotypes of dysthymia: evolutionary, clinical and pharmacogenomic considerations

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An apparently dominant bipolar affective disorder (BPAD) locus on chromosome 20p11.2–q11.2 in a large Turkish pedigree

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Gene expression and association analysis of LIM (PDLIM5) in major depression

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A halotype-based study of lithium responding patients with bipolar affective disorder on the Faroe Islands

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Linkage and association between serotonin 2A receptor gene polymorphisms and bipolar I disorder

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Association analyses of the neuregulin 1 gene with schizophrenia and manic psychosis in a Hispanic population

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Impact of Venlafaxine on Gene Expression Profile in Lymphocytes of the Elderly with Major Depression – Evolution of Antidepressants and the Role of the “Neuro-Immune” System

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Association study of nicotinic-receptor variants and major depressive disorder

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A Promoter Haplotype of the Inositol Monophosphatase 2 Gene (IMPA2) at 18p11.2 Confers a Possible Risk for Bipolar Disorder by Enhancing Transcription

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PC12 cell model of inducible expression of mutant DISC1: New evidence for a dominant-negative mechanism of abnormal neuronal differentiation

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Drug-Induced Decrease of Protein Kinase A Activity Reveals Alteration in BDNF Expression of Bipolar Affective Disorder

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Suggestive linkage of a chromosomal locus on 18p11 to cyclothymic temperament in bipolar disorder families

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Additional, physically ordered markers increase linkage signal for bipolar disorder on chromosome 18q22

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Association study of bipolar disorder using a functional polymorphism (Ser311→Cys) in the dopamine D2 receptor gene

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A functional polymorphism of the µ-opioid receptor gene is associated with completed suicides

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Association analysis of the glycogen synthase kinase-3β gene in bipolar disorder

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Convergent functional genomics: application to bipolar disorder

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Association of ALDH1 Promoter Polymorphisms With Alcohol-Related Phenotypes in Trinidad and Tobago*

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Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations

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Analysis of Synapsin III –196 Promoter Mutation in Schizophrenia and Bipolar Disorder

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Genomics and genome-wide association studies: An integrative approach to expression QTL mapping

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Finding Genes for Bipolar Disorder in the Functional Genomics Era: From Convergent Functional Genomics to Phenomics and Back

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Association analysis of the pituitary adenyl cyclase activating peptide gene (PACAP) on chromosome 18p11 with schizophrenia and bipolar disorders

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Possible linkage of schizophrenia and bipolar affective disorder to chromosome 3q29

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Sex Hormones, Darwinism, and Depression

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Genomic studies of mood disorders -- the brain as a muscle?

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Genetic linkage and bipolar disorder: a cautionary note

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MET BDNF protects against morphological S allele effects of 5-HTTLPR

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ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

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Circadian rhythm disruption and mental health

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The genetics of bipolar disorder

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Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker in bipolar disorder: a meta-analysis of 52 studies

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Traumatic stress, oxidative stress and post-traumatic stress disorder: neurodegeneration and the accelerated-aging hypothesis

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Biomarkers in bipolar disorder: a positional paper from the international society for bipolar disorders biomarkers task force.

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Identification of Pathways for Bipolar Disorder: A Meta-analysis

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RBFOX1 regulates both splicing and transcriptional networks in human neuronal development

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Discovery and validation of blood biomarkers for suicidality

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Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci

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SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorder

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Interactions of the serotonin and circadian systems: nature and nurture in rhythms and blues

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Genetic approaches to understanding post-traumatic stress disorder

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Sleep- and circadian rhythm–associated pathways as therapeutic targets in bipolar disorder

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Orchestration of Neurodevelopmental Programs by RBFOX1

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NFIB haploinsufficiency is associated with intellectual disability and macrocephaly

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Gene expression alterations in bipolar disorder postmortem brains

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Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder

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Developmental Expression Mapping of a Gene Implicated in Multiple Neurodevelopmental Disorders, &lt;i&gt;A2bp1 (Fox1)&lt;/i&gt;

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Genetics and erectile dysfunction: leveraging early foundations for new discoveries

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Lessons and implications from association studies and post-GWAS analyses of cervical cancer

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Protein-Protein interactions uncover candidate ‘core genes’ within omnigenic disease networks

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Genetic Architecture of Depression: Where Do We Stand Now?

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Gene and Pathway-Based Analysis: Second Wave of Genome-wide Association Studies

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