Arolt, Volker

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

eQTLGen, Wray, N. R., 23andMe, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 3,005

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

Howard, D. M., Adams, M. J., Clarke, T.-K., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., et al. (2019) · Nature Neuroscience

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 2,565

Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group

for the ENIGMA-Major Depressive Disorder Working Group, Schmaal, L., Hibar, D. P., Sämann, P. G., Hall, G. B., Baune, B. T., Jahanshad, N., Cheung, J. W., van Erp, T. G. M., Bos, D., et al. (2017) · Molecular Psychiatry

Treatment of Major DepressionNeural and Behavioral Psychology Studies

Cited by 1,330

Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging

Dannlowski, U., Stuhrmann, A., Beutelmann, V., Zwanzger, P., Lenzen, T., Grotegerd, D., Domschke, K., Hohoff, C., Ohrmann, P., Bauer, J., et al. (2012) · Biological Psychiatry

Child Abuse and TraumaPosttraumatic Stress Disorder Research

Cited by 954

Human Fear Conditioning and Extinction in Neuroimaging: A Systematic Review

Sehlmeyer, C., Schöning, S., Zwitserlood, P., Pfleiderer, B., Kircher, T., Arolt, V., & Konrad, C. (2009) · PLoS ONE

Memory and Neural MechanismsNeural and Behavioral Psychology Studies

Cited by 543

Childhood maltreatment is associated with an automatic negative emotion processing bias in the amygdala

Dannlowski, U., Kugel, H., Huber, F., Stuhrmann, A., Redlich, R., Grotegerd, D., Dohm, K., Sehlmeyer, C., Konrad, C., Baune, B. T., et al. (2013) · Human Brain Mapping

Child Abuse and TraumaStress Responses and Cortisol

Cited by 249

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., et al. (2022) · Biological Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 238

Reduced amygdala–prefrontal coupling in major depression: association with MAOA genotype and illness severity

Dannlowski, U., Ohrmann, P., Konrad, C., Domschke, K., Bauer, J., Kugel, H., Hohoff, C., Schöning, S., Kersting, A., Baune, B. T., et al. (2009) · The International Journal of Neuropsychopharmacology

Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on Behavior

Cited by 216

Hippocampal atrophy in major depression: a function of childhood maltreatment rather than diagnosis?

Opel, N., Redlich, R., Zwanzger, P., Grotegerd, D., Arolt, V., Heindel, W., Konrad, C., Kugel, H., & Dannlowski, U. (2014) · Neuropsychopharmacology

Child Abuse and TraumaStress Responses and Cortisol

Cited by 214

Oxytocin receptor gene methylation: converging multilevel evidence for a role in social anxiety

Ziegler, C., Dannlowski, U., Bräuer, D., Stevens, S., Laeger, I., Wittmann, H., Kugel, H., Dobel, C., Hurlemann, R., Reif, A., et al. (2015) · Neuropsychopharmacology

Neuroendocrine regulation and behaviorAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 193

MAOA gene hypomethylation in panic disorder-reversibility of an epigenetic risk pattern by psychotherapy

Ziegler, C., Richter, J., Mahr, M., Gajewska, A., Schiele, M. A., Gehrmann, A., Schmidt, B., Lesch, K.-P., Lang, T., Helbig-Lang, S., et al. (2016) · Translational Psychiatry

Epigenetics and DNA MethylationAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 183

Neural correlates of trait anxiety in fear extinction

Sehlmeyer, C., Dannlowski, U., Schöning, S., Kugel, H., Pyka, M., Pfleiderer, B., Zwitserlood, P., Schiffbauer, H., Heindel, W., Arolt, V., et al. (2011) · Psychological Medicine

Memory and Neural MechanismsAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 165

Insular and hippocampal gray matter volume reductions in patients with major depressive disorder

Stratmann, M., Konrad, C., Kugel, H., Krug, A., Schöning, S., Ohrmann, P., Uhlmann, C., Postert, C., Suslow, T., Heindel, W., et al. (2014) · PLoS ONE

Treatment of Major DepressionNeural and Behavioral Psychology Studies

Cited by 164

Reward processing in unipolar and bipolar depression: A functional MRI study

Redlich, R., Dohm, K., Grotegerd, D., Opel, N., Zwitserlood, P., Heindel, W., Arolt, V., Kugel, H., & Dannlowski, U. (2015) · Neuropsychopharmacology

Bipolar Disorder and TreatmentNeural and Behavioral Psychology Studies

Cited by 164

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., et al. (2019) · Nature Communications

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 143

The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response

Biernacka, J. M., Sangkuhl, K., Jenkins, G., Whaley, R. M., Barman, P., Batzler, A., Altman, R. B., Arolt, V, Brockmöller, J., Chen, C. H., et al. (2015) · Translational Psychiatry

Treatment of Major DepressionGenetic Associations and Epidemiology

Cited by 140

Obesity and major depression: body-mass index (BMI) is associated with a severe course of disease and specific neurostructural alterations

Opel, N., Redlich, R., Grotegerd, D., Dohm, K., Heindel, W., Kugel, H., Arolt, V., & Dannlowski, U. (2015) · Psychoneuroendocrinology

Treatment of Major DepressionNeural and Behavioral Psychology Studies

Cited by 138

Systematic misestimation of machine learning performance in neuroimaging studies of depression

Flint, C., Cearns, M., Opel, N., Redlich, R., Mehler, D. M. A., Emden, D., Winter, N. R., Leenings, R., Eickhoff, S. B., Kircher, T., et al. (2021) · Neuropsychopharmacology

Functional Brain Connectivity StudiesArtificial Intelligence in Healthcare

Cited by 120

Cognitive impairment and in vivo metabolites in first-episode neuroleptic-naive and chronic medicated schizophrenic patients: a proton magnetic resonance spectroscopy study

Ohrmann, P., Siegmund, A., Suslow, T., Pedersen, A., Spitzberg, K., Kersting, A., Rothermundt, M., Arolt, V., Heindel, W., & Pfleiderer, B. (2007) · Journal of Psychiatric Research

Schizophrenia research and treatmentAdvanced MRI Techniques and Applications

Cited by 116

S100B potently activates p65/c-Rel transcriptional complexes in hippocampal neurons: Clinical implications for the role of S100B in excitotoxic brain injury

Kögel, D., Peters, M., König, H.-G., Hashemi, S. M. A., Bui, N. T., Arolt, V., Rothermundt, M., & Prehn, J. H. M. (2004) · Neuroscience

S100 Proteins and AnnexinsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 82

Working‐memory fMRI reveals cingulate hyperactivation in euthymic major depression

Schöning, S., Zwitserlood, P., Engelien, A., Behnken, A., Kugel, H., Schiffbauer, H., Lipina, K., Pachur, C., Kersting, A., Dannlowski, U., et al. (2009) · Human Brain Mapping

Neural and Behavioral Psychology StudiesTreatment of Major Depression

Cited by 81

Neural activation underlying acute grief in women after the loss of an unborn child

Kersting, A., Ohrmann, P., Pedersen, A., Kroker, K., Samberg, D., Bauer, J., Kugel, H., Koelkebeck, K., Steinhard, J., Heindel, W., et al. (2009) · American Journal of Psychiatry

Grief, Bereavement, and Mental HealthDeath Anxiety and Social Exclusion

Cited by 67

Attachment style and oxytocin receptor gene variation interact in influencing social anxiety

Notzon, S., Domschke, K., Holitschke, K., Ziegler, C., Arolt, V., Pauli, P., Reif, A., Deckert, J., & Zwanzger, P. (2016) · The World Journal of Biological Psychiatry

Neuroendocrine regulation and behaviorAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 65