Stark, George R.

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

Darnell, J. E., Kerr, L. M., & Stark, G. R. (1994) · Science

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 6,080

HOW CELLS RESPOND TO INTERFERONS

Stark, G. R., Kerr, I. M., Williams, B. R. G., Silverman, R. H., & Schreiber, R. D. (1998) · Annual Review of Biochemistry

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 3,932

Interferons at age 50: past, current and future impact on biomedicine

Borden, E. C., Sen, G. C., Uze, G., Silverman, R. H., Ransohoff, R. M., Foster, G. R., & Stark, G. R. (2007) · Nature Reviews Drug Discovery

interferon and immune responsesImmune Response and Inflammation

Cited by 1,154

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.

Agarwal, M. L., Agarwal, A., Taylor, W. R., & Stark, G. R. (1995) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 858

A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

Shuai, K., Stark, G. R., Kerr, L. M., & Darnell, J. E. (1993) · Science

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 802

Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFκB

Yang, J., Liao, X., Agarwal, M. K., Barnes, L., Auron, P. E., & Stark, G. R. (2007) · Genes & Development

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 611

Stat1-dependent and -independent pathways in IFN-γ-dependent signaling

Ramana, C. V., Gil, M. P., Schreiber, R. D., & Stark, G. R. (2002) · Trends in Immunology

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 555

Complex modulation of cell type-specific signaling in response to type I interferons

van Boxel-Dezaire, A. H. H., Rani, M. R. S., & Stark, G. R. (2006) · Immunity

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 530

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon‐alpha and ‐gamma signal transduction pathways.

Müller, M., Laxton, C., Briscoe, J., Schindler, C., Improta, T., Darnell, J. E., Stark, G. R., & Kerr, I. M. (1993) · The EMBO Journal

interferon and immune responsesCytokine Signaling Pathways and Interactions

Cited by 411

Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation

Yang, J., Chatterjee-Kishore, M., Staugaitis, S. M., Nguyen, H., Schlessinger, K., Levy, D. E., & Stark, G. R. (2005) · Cancer Research

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

Cited by 405

Roles of unphosphorylated STATs in signaling

Yang, J., & Stark, G. R. (2008) · Cell Research

Cytokine Signaling Pathways and InteractionsGenomics and Chromatin Dynamics

Cited by 347

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

Yang, J., Huang, J., Dasgupta, M., Sears, N., Miyagi, M., Wang, B., Chance, M. R., Chen, X., Du, Y., Wang, Y., et al. (2010) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsGenomics and Chromatin Dynamics

Cited by 340

STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor

Wang, Y., van Boxel-Dezaire, A. H. H., Cheon, H., Yang, J., & Stark, G. R. (2013) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 327

Levels of HdmX expression dictate the sensitivity of normal and transformed cells to Nutlin-3

Patton, J. T., Mayo, L. D., Singhi, A. D., Gudkov, A. V., Stark, G. R., & Jackson, M. W. (2006) · Cancer Research

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 189

p130/E2F4 Binds to and Represses the cdc2 Promoter in Response to p53

Taylor, W. R., Schönthal, A. H., Galante, J., & Stark, G. R. (2001) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 110

p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2

Jackson, M. W., Agarwal, M. K., Yang, J., Bruss, P., Uchiumi, T., Agarwal, M. L., Stark, G. R., & Taylor (2005) · Journal of Cell Science

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 92

Critical Role for Lysine 685 in Gene Expression Mediated by Transcription Factor Unphosphorylated STAT3

Dasgupta, M., Unal, H., Willard, B., Yang, J., Karnik, S. S., & Stark, G. R. (2014) · Journal of Biological Chemistry

Cytokine Signaling Pathways and InteractionsGenomics and Chromatin Dynamics

Cited by 64

Hdm2 Nuclear Export, Regulated by Insulin-like Growth Factor-I/MAPK/p90Rsk Signaling, Mediates the Transformation of Human Cells

Jackson, M. W., Patt, L. E., LaRusch, G. A., Donner, D. B., Stark, G. R., & Mayo, L. D. (2006) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 29