Nedergaard, Maiken

Astroglial cradle in the life of the synapse

Verkhratsky, A., & Nedergaard, M. (2014) · Philosophical Transactions of the Royal Society B: Biological Sciences

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 266

The glymphatic system: implications for drugs for central nervous system diseases

Lohela, T. J., Lilius, T. O., & Nedergaard, M. (2022) · Nature Reviews Drug Discovery

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 254

Critical role of aquaporin-4 (AQP4) in astrocytic Ca 2+ signaling events elicited by cerebral edema

Thrane, A. S., Rappold, P. M., Fujita, T., Torres, A., Bekar, L. K., Takano, T., Peng, W., Wang, F., Rangroo Thrane, V., Enger, R., et al. (2011) · Proceedings of the National Academy of Sciences

Ion Transport and Channel RegulationCerebrospinal fluid and hydrocephalus

Cited by 254

Alexander Disease

Messing, A., Brenner, M., Feany, M. B., Nedergaard, M., & Goldman, J. E. (2012) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 250

Glymphatic influx and clearance are accelerated by neurovascular coupling

Holstein-Rønsbo, S., Gan, Y., Giannetto, M. J., Rasmussen, M. K., Sigurdsson, B., Beinlich, F. R. M., Rose, L., Untiet, V., Hablitz, L. M., Kelley, D. H., et al. (2023) · Nature Neuroscience

Cerebrospinal fluid and hydrocephalusTraumatic Brain Injury and Neurovascular Disturbances

Cited by 248

Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET

de Leon, M. J., Li, Y., Okamura, N., Tsui, W. H., Saint-Louis, L. A., Glodzik, L., Osorio, R. S., Fortea, J., Butler, T., Pirraglia, E., et al. (2017) · Journal of Nuclear Medicine

Cerebrospinal fluid and hydrocephalusAlzheimer's disease research and treatments

Cited by 246

Anesthesia with Dexmedetomidine and Low-dose Isoflurane Increases Solute Transport via the Glymphatic Pathway in Rat Brain When Compared with High-dose Isoflurane

Benveniste, H., Lee, H., Ding, F., Sun, Q., Al-Bizri, E., Makaryus, R., Probst, S., Nedergaard, M., Stein, E. A., & Lu, H. (2017) · Anesthesiology

Cerebrospinal fluid and hydrocephalusAnesthesia and Sedative Agents

Cited by 236

Glial Biology in Learning and Cognition

Fields, R. D., Araque, A., Johansen-Berg, H., Lim, S.-S., Lynch, G., Nave, K.-A., Nedergaard, M., Perez, R., Sejnowski, T., & Wake, H. (2014) · The Neuroscientist

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 232

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease

Benraiss, A., Wang, S., Herrlinger, S., Li, X., Chandler-Militello, D., Mauceri, J., Burm, H. B., Toner, M., Osipovitch, M., Jim Xu, Q., et al. (2016) · Nature Communications

Genetic Neurodegenerative DiseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 199

Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema

Hussain, R., Tithof, J., Wang, W., Cheetham-West, A., Song, W., Peng, W., Sigurdsson, B., Kim, D., Sun, Q., Peng, S., et al. (2023) · Nature

Traumatic Brain Injury and Neurovascular DisturbancesCerebrospinal fluid and hydrocephalus

Cited by 169

Two-photon NADH imaging exposes boundaries of oxygen diffusion in cortical vascular supply regions

Kasischke, K. A., Lambert, E. M., Panepento, B., Sun, A., Gelbard, H. A., Burgess, R. W., Foster, T. H., & Nedergaard, M. (2011) · Journal of Cerebral Blood Flow & Metabolism

Optical Imaging and Spectroscopy TechniquesAdvanced Fluorescence Microscopy Techniques

Cited by 160

The pathophysiology underlying repetitive mild traumatic brain injury in a novel mouse model of chronic traumatic encephalopathy.

Petraglia, A., Plog, B., Dayawansa, S., Dashnaw, M., Czerniecka, K., Walker, C., Chen, M., Hyrien, O., Iliff, J., Deane, R., et al. (2014) · Surgical Neurology International

Traumatic Brain Injury ResearchTraumatic Brain Injury and Neurovascular Disturbances

Cited by 151

Voluntary running enhances glymphatic influx in awake behaving, young mice

von Holstein-Rathlou, S., Petersen, N. C., & Nedergaard, M. (2018) · Neuroscience Letters

Cerebrospinal fluid and hydrocephalusTraumatic Brain Injury and Neurovascular Disturbances

Cited by 147

Neuronal Transgene Expression in Dominant-Negative SNARE Mice

Fujita, T., Chen, M. J., Li, B., Smith, N. A., Peng, W., Sun, W., Toner, M. J., Kress, B. T., Wang, L., Benraiss, A., et al. (2014) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 141

The homeostatic astroglia emerges from evolutionary specialization of neural cells

Verkhratsky, A., & Nedergaard, M. (2016) · Philosophical Transactions of the Royal Society B: Biological Sciences

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 133

Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations

Helakari, H., Korhonen, V., Holst, S. C., Piispala, J., Kallio, M., Väyrynen, T., Huotari, N., Raitamaa, L., Tuunanen, J., Kananen, J., et al. (2022) · The Journal of Neuroscience

Sleep and Wakefulness ResearchCerebrospinal fluid and hydrocephalus

Cited by 131

Brain energetics during the sleep-wake cycle

DiNuzzo, M., & Nedergaard, M. (2017) · Current Opinion in Neurobiology

Sleep and Wakefulness ResearchNeuroscience and Neuropharmacology Research

Cited by 130

Cleaning the sleeping brain – the potential restorative function of the glymphatic system

Hauglund, N. L., Pavan, C., & Nedergaard, M. (2020) · Current Opinion in Physiology

Cerebrospinal fluid and hydrocephalusSleep and Wakefulness Research

Cited by 129

Quantitative Gd‐DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA‐SPGR at 9.4T

Lee, H., Mortensen, K., Sanggaard, S., Koch, P., Brunner, H., Quistorff, B., Nedergaard, M., & Benveniste, H. (2018) · Magnetic Resonance in Medicine

Advanced MRI Techniques and ApplicationsNMR spectroscopy and applications

Cited by 110

Cerebral Metabolic Changes During Sleep

Aalling, N. N., Nedergaard, M., & DiNuzzo, M. (2018) · Current Neurology and Neuroscience Reports

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 101

Oxygen imaging of hypoxic pockets in the mouse cerebral cortex

Beinlich, F. R. M., Asiminas, A., Untiet, V., Bojarowska, Z., Plá, V., Sigurdsson, B., Timmel, V., Gehrig, L., Graber, M. H., Hirase, H., et al. (2024) · Science

Optical Imaging and Spectroscopy TechniquesAdvanced Fluorescence Microscopy Techniques

Cited by 82

5-HT 2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional ‘serotonin-specific reuptake inhibitors’

Zhang, S., Li, B., Lovatt, D., Xu, J., Song, D., Goldman, S. A., Nedergaard, M., Hertz, L., & Peng, L. (2010) · Neuron Glia Biology

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 69

A real-time in vivo clearance assay for quantification of glymphatic efflux

Plá, V., Bork, P., Harnpramukkul, A., Olveda, G., Ladrón-de-Guevara, A., Giannetto, M. J., Hussain, R., Wang, W., Kelley, D. H., Hablitz, L. M., et al. (2022) · Cell Reports

Cerebrospinal fluid and hydrocephalusIon Transport and Channel Regulation

Cited by 64

B lymphocytes ameliorate Alzheimer’s disease-like neuropathology via interleukin-35

Feng, W., Zhang, Y., Ding, S., Chen, S., Wang, T., Wang, Z., Zou, Y., Sheng, C., Chen, Y., Pang, Y., et al. (2023) · Brain, Behavior, and Immunity

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 62