Chambon, Pierre

The nuclear receptor superfamily: the second decade

Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., et al. (1995) · Cell

Estrogen and related hormone effectsNuclear Receptors and Signaling

Cited by 6,964

A decade of molecular biology of retinoic acid receptors

Chambon, P. (1996) · The FASEB Journal

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 2,889

A human retinoic acid receptor which belongs to the family of nuclear receptors

Petkovich, M., Brand, N. J., Krust, A., & Chambon, P. (1987) · Nature

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 2,214

Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

Kato, S., Endoh, H., Masuhiro, Y., Kitamoto, T., Uchiyama, S., Sasaki, H., Masushige, S., Gotoh, Y., Nishida, E., Kawashima, H., et al. (1995) · Science

Estrogen and related hormone effectsProtein Kinase Regulation and GTPase Signaling

Cited by 1,964

Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B

Kastner, P., Krust, A., Turcotte, B., Stropp, U., Tora, L., Gronemeyer, H., & Chambon, P. (1990) · The EMBO Journal

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 1,534

Functional domains of the human estrogen receptor

Kumar, V., Green, S., Stack, G., Berry, M., Jin, J.-R., & Chambon, P. (1987) · Cell

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 1,316

In vivo sequence requirements of the SV40 early promoter region

Benoist, C., & Chambon, P. (1981) · Nature

Genomics and Chromatin DynamicsPolyomavirus and related diseases

Cited by 1,074

Effect of single and compound knockouts of estrogen receptors α (ERα) and β (ERβ) on mouse reproductive phenotypes

Dupont, S., Krust, A., Gansmuller, A., Dierich, A., Chambon, P., & Mark, M. (2000) · Development

Estrogen and related hormone effectsReproductive Biology and Fertility

Cited by 1,064

Estrogen Prevents Bone Loss via Estrogen Receptor α and Induction of Fas Ligand in Osteoclasts

Nakamura, T., Imai, Y., Matsumoto, T., Sato, S., Takeuchi, K., Igarashi, K., Harada, Y., Azuma, Y., Krust, A., Yamamoto, Y., et al. (2007) · Cell

Bone Metabolism and DiseasesEstrogen and related hormone effects

Cited by 1,013

Ligand-activated site-specific recombination in mice.

Feil, R., Brocard, J., Mascrez, B., LeMeur, M., Metzger, D., & Chambon, P. (1996) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 907

Multiplicity generates diversity in the retinoic acid signalling pathways

Leid, M., Kastner, P., & Chambon, P. (1992) · Trends in Biochemical Sciences

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 821

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

Moreau, P., Hen, R., Wasylyk, B., Everett, R., Gaub, M. P., & Chambon, P. (1981) · Nucleic Acids Research

Polyomavirus and related diseasesGenomics and Chromatin Dynamics

Cited by 761

Nicotinamide mononucleotide activation of a new DNA-dependent polyadenylic acid synthesizing nuclear enzyme

Chambon, P., Weill, J. D., & Mandel, P. (1963) · Biochemical and Biophysical Research Communications

Advanced biosensing and bioanalysis techniquesElectrochemical sensors and biosensors

Cited by 654

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18

Le Douarin, B., Zechel, C., Garnier, J. M., Lutz, Y., Tora, L., Pierrat, P., Heery, D., Gronemeyer, H., Chambon, P., & Losson, R. (1995) · The EMBO Journal

Estrogen and related hormone effectsNuclear Receptors and Signaling

Cited by 619

Regeneration of fat cells from myofibroblasts during wound healing

Plikus, M. V., Guerrero-Juarez, C. F., Ito, M., Li, Y. R., Dedhia, P. H., Zheng, Y., Shao, M., Gay, D. L., Ramos, R., Hsi, T.-C., et al. (2017) · Science

Wound Healing and TreatmentsHair Growth and Disorders

Cited by 584

Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase.

Metzger, D., Clifford, J., Chiba, H., & Chambon, P. (1995) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 570

Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs

Mukherji, A., Kobiita, A., Ye, T., & Chambon, P. (2013) · Cell

Circadian rhythm and melatoninGut microbiota and health

Cited by 560

Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor

Surjit, M., Ganti, K. P., Mukherji, A., Ye, T., Hua, G., Metzger, D., Li, M., & Chambon, P. (2011) · Cell

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 551

Retinoid X receptor gamma signaling accelerates CNS remyelination

Huang, J. K., Jarjour, A. A., Nait Oumesmar, B., Kerninon, C., Williams, A., Krezel, W., Kagechika, H., Bauer, J., Zhao, C., Evercooren, A. B.-V., et al. (2011) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 547

Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development

Niederreither, K., McCaffery, P., Dräger, U. C., Chambon, P., & Dollé, P. (1997) · Mechanisms of Development

Retinoids in leukemia and cellular processesDevelopmental Biology and Gene Regulation

Cited by 523

International Union of Pharmacology. LXIII. Retinoid X receptors

Germain, P., Chambon, P., Eichele, G., Evans, R. M., Lazar, M. A., Leid, M., De Lera, A. R., Lotan, R., Mangelsdorf, D. J., & Gronemeyer, H. (2006) · Pharmacological Reviews

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 496

Impaired skin wound healing in peroxisome proliferator–activated receptor (PPAR)α and PPAR β mutant mice

Michalik, L., Desvergne, B., Tan, N. S., Basu-Modak, S., Escher, P., Rieusset, J., Peters, J. M., Kaya, G., Gonzalez, F. J., Zakany, J., et al. (2001) · The Journal of Cell Biology

Peroxisome Proliferator-Activated ReceptorsWound Healing and Treatments

Cited by 406

Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

Kadkhodaei, B., Ito, T., Joodmardi, E., Mattsson, B., Rouillard, C., Carta, M., Muramatsu, S.-I., Sumi-Ichinose, C., Nomura, T., Metzger, D., et al. (2009) · The Journal of Neuroscience

Nuclear Receptors and SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 382

Function of retinoic acid receptors during embryonic development

Mark, M., Ghyselinck, N. B., & Chambon, P. (2009) · Nuclear Receptor Signaling

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 363