Schrauwen, Patrick

High-fat diet, muscular lipotoxicity and insulin resistance

Schrauwen, P. (2007) · Proceedings of the Nutrition Society

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 153

Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise

Catoire, M., Alex, S., Paraskevopulos, N., Mattijssen, F., Evers-van Gogh, I., Schaart, G., Jeppesen, J., Kneppers, A., Mensink, M., Voshol, P. J., et al. (2014) · Proceedings of the National Academy of Sciences

Lipid metabolism and disordersPeroxisome Proliferator-Activated Receptors

Cited by 150

Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels

Bosma, M., Hesselink, M. K. C., Sparks, L. M., Timmers, S., Ferraz, M. J., Mattijssen, F., van Beurden, D., Schaart, G., de Baets, M. H., Verheyen, F. K., et al. (2012) · Diabetes

Lipid metabolism and biosynthesisAdipose Tissue and Metabolism

Cited by 149

Effect of training in the fasted state on metabolic responses during exercise with carbohydrate intake

De Bock, K., Derave, W., Eijnde, B. O., Hesselink, M. K., Koninckx, E., Rose, A. J., Schrauwen, P., Bonen, A., Richter, E. A., & Hespel, P. (2008) · Journal of Applied Physiology

Muscle metabolism and nutritionCardiovascular and exercise physiology

Cited by 144

The effects of 30-days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men

Konings, E., Timmers, S., Boekschoten, M. V., Goossens, G. H., Jocken, J. W., Afman, L. A., Müller, M., Schrauwen, P., Mariman, E. C., & Blaak, E. E. (2014) · International Journal of Obesity

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 143

Evidence for a Direct Effect of the NAD+ Precursor Acipimox on Muscle Mitochondrial Function in Humans

van de Weijer, T., Phielix, E., Bilet, L., Williams, E. G., Ropelle, E. R., Bierwagen, A., Livingstone, R., Nowotny, P., Sparks, L. M., Paglialunga, S., et al. (2015) · Diabetes

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 139

Resveratrol and obesity: can resveratrol relieve metabolic disturbances?

de Ligt, M., Timmers, S., & Schrauwen, P. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 135

Human Skeletal Muscle Mitochondrial Uncoupling Is Associated with Cold Induced Adaptive Thermogenesis

Wijers, S. L. J., Schrauwen, P., Saris, W. H. M., & van Marken Lichtenbelt, W. D. (2008) · PLoS ONE

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 135

Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians.

Schrauwen, P., Xia, J., Bogardus, C., Pratley, R. E., & Ravussin, E. (1999) · Diabetes

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 129

Three weeks on a high-fat diet increases intrahepatic lipid accumulation and decreases metabolic flexibility in healthy overweight men

van Herpen, N. A., Schrauwen-Hinderling, V. B., Schaart, G., Mensink, R. P., & Schrauwen, P. (2011) · The Journal of Clinical Endocrinology & Metabolism

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 124

Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes

Sparks, L. M., Johannsen, N. M., Church, T. S., Earnest, C. P., Moonen-Kornips, E., Moro, C., Hesselink, M. K. C., Smith, S. R., & Schrauwen, P. (2013) · The Journal of Clinical Endocrinology & Metabolism

Cardiovascular and exercise physiologyAdipose Tissue and Metabolism

Cited by 123

TNF-α impairs regulation of muscle oxidative phenotype: implications for cachexia?

Remels, A. H. V., Gosker, H. R., Schrauwen, P., Hommelberg, P. P. H., Sliwinski, P., Polkey, M., Galdiz, J., Wouters, E. F. M., Langen, R. C. J., & Schols, A. M. W. J. (2010) · The FASEB Journal

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 122

Pronounced Effects of Acute Endurance Exercise on Gene Expression in Resting and Exercising Human Skeletal Muscle

Catoire, M., Mensink, M., Boekschoten, M. V., Hangelbroek, R., Müller, M., Schrauwen, P., & Kersten, S. (2012) · PLoS ONE

Exercise and Physiological ResponsesCardiovascular and exercise physiology

Cited by 116

Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes

Schrauwen, P., Hesselink, M. K. C., Blaak, E. E., Borghouts, L. B., Schaart, G., Saris, W. H. M., & Keizer, H. A. (2001) · Diabetes

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 112

Healthy aging and muscle function are positively associated with NAD+ abundance in humans

Janssens, G. E., Grevendonk, L., Perez, R. Z., Schomakers, B. V., de Vogel-van den Bosch, J., Geurts, J. M. W., van Weeghel, M., Schrauwen, P., Houtkooper, R. H., & Hoeks, J. (2022) · Nature Aging

Sirtuins and Resveratrol in MedicineNutrition and Health in Aging

Cited by 103

Glucose ingestion during exercise blunts exercise-induced gene expression of skeletal muscle fat oxidative genes

Civitarese, A. E., Hesselink, M. K. C., Russell, A. P., Ravussin, E., & Schrauwen, P. (2005) · American Journal of Physiology-Endocrinology and Metabolism

Muscle metabolism and nutritionMetabolism, Diabetes, and Cancer

Cited by 99

High Oxidative Capacity Due to Chronic Exercise Training Attenuates Lipid-Induced Insulin Resistance

Phielix, E., Meex, R., Ouwens, D. M., Sparks, L., Hoeks, J., Schaart, G., Moonen-Kornips, E., Hesselink, M. K. C., & Schrauwen, P. (2012) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 99

Muscle mitochondria and insulin resistance: a human perspective

Hoeks, J., & Schrauwen, P. (2012) · Trends in Endocrinology & Metabolism

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 94

Effects of exercise training on intrahepatic lipid content in humans

Brouwers, B., Hesselink, M. K. C., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2016) · Diabetologia

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 94

Relationships between Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes Mellitus

van de Weijer, T., Sparks, L. M., Phielix, E., Meex, R. C., van Herpen, N. A., Hesselink, M. K. C., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2013) · PLoS ONE

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 87

Human Uncoupling Protein‐3 and Obesity: An Update

Hesselink, M. K. C., Mensink, M., & Schrauwen, P. (2003) · Obesity Research

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 85

Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

Houzelle, A., Jörgensen, J. A., Schaart, G., Daemen, S., van Polanen, N., Fealy, C. E., Hesselink, M. K. C., Schrauwen, P., & Hoeks, J. (2021) · Diabetologia

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 83

Increased uncoupling protein 3 content does not affect mitochondrial function in human skeletal muscle in vivo

Hesselink, M. K. C., Greenhaff, P. L., Constantin-Teodosiu, D., Hultman, E., Saris, W. H. M., Nieuwlaat, R., Schaart, G., Kornips, E., & Schrauwen, P. (2003) · Journal of Clinical Investigation

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 82

Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity

Timmers, S., Nabben, M., Bosma, M., van Bree, B., Lenaers, E., van Beurden, D., Schaart, G., Westerterp-Plantenga, M. S., Langhans, W., Hesselink, M. K. C., et al. (2012) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 80