Tang, Weiping

Development of the first small molecule histone deacetylase 6 (HDAC6) degraders

Yang, K., Song, Y., Xie, H., Wu, H., Wu, Y.-T., Leisten, E. D., & Tang, W. (2018) · Bioorganic & Medicinal Chemistry Letters

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

Cited by 190

Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity

Wu, H., Yang, K., Zhang, Z., Leisten, E. D., Li, Z., Xie, H., Liu, J., Smith, K. A., Novakova, Z., Barinka, C., et al. (2019) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

Cited by 180

A marine microbiome antifungal targets urgent-threat drug-resistant fungi

Zhang, F., Zhao, M., Braun, D. R., Ericksen, S. S., Piotrowski, J. S., Nelson, J., Peng, J., Ananiev, G. E., Chanana, S., Barns, K., et al. (2020) · Science

Microbial Natural Products and BiosynthesisMarine Sponges and Natural Products

Cited by 177

Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR)

Seok, S.-H., Ma, Z.-X., Feltenberger, J. B., Chen, H., Chen, H., Scarlett, C., Lin, Z., Satyshur, K. A., Cortopassi, M., Jefcoate, C. R., et al. (2018) · Journal of Biological Chemistry

Tryptophan and brain disordersToxic Organic Pollutants Impact

Cited by 157

Development of Selective Histone Deacetylase 6 (HDAC6) Degraders Recruiting Von Hippel–Lindau (VHL) E3 Ubiquitin Ligase

Yang, K., Wu, H., Zhang, Z., Leisten, E. D., Nie, X., Liu, B., Wen, Z., Zhang, J., Cunningham, M. D., & Tang, W. (2020) · ACS Medicinal Chemistry Letters

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

Cited by 124

Development of selective small molecule MDM2 degraders based on nutlin

Wang, B., Wu, S., Liu, J., Yang, K., Xie, H., & Tang, W. (2019) · European Journal of Medicinal Chemistry

Protein Degradation and InhibitorsCancer-related Molecular Pathways

Cited by 77

Development of MDM2 degraders based on ligands derived from Ugi reactions: Lessons and discoveries

Wang, B., Liu, J., Tandon, I., Wu, S., Teng, P., Liao, J., & Tang, W. (2021) · European Journal of Medicinal Chemistry

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 67

In Silico Modeling and Scoring of PROTAC-Mediated Ternary Complex Poses

Liao, J., Nie, X., Unarta, I. C., Ericksen, S. S., & Tang, W. (2022) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsComputational Drug Discovery Methods

Cited by 62

In Silico Modeling and Scoring of PROTAC-Mediated Ternary Complex Poses

Liao, J., Nie, X., Unarta, I., Ericksen, S., & Tang, W. (2021) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsComputational Drug Discovery Methods

Cited by 62