Bertozzi, Carolyn R.

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

Sletten, E. M., & Bertozzi, C. R. (2009) · Angewandte Chemie International Edition

Click Chemistry and ApplicationsAdvanced Polymer Synthesis and Characterization

Cited by 3,165

Cu-free click cycloaddition reactions in chemical biology

Jewett, J. C., & Bertozzi, C. R. (2010) · Chemical Society Reviews

Click Chemistry and ApplicationsOrganic Chemistry Cycloaddition Reactions

Cited by 1,684

Lipid droplet accumulating microglia represent a dysfunctional and pro-inflammatory state in the aging brain

Marschallinger, J., Iram, T., Zardeneta, M., Lee, S. E., Lehallier, B., Haney, M. S., Pluvinage, J. V., Mathur, V., Hahn, O., Morgens, D. W., et al. (2019) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 1,414

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

Marschallinger, J., Iram, T., Zardeneta, M., Lee, S. E., Lehallier, B., Haney, M. S., Pluvinage, J. V., Mathur, V., Hahn, O., Morgens, D. W., et al. (2020) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 1,384

Lysosome-targeting chimaeras for degradation of extracellular proteins

Banik, S. M., Pedram, K., Wisnovsky, S., Ahn, G., Riley, N. M., & Bertozzi, C. R. (2020) · Nature

Protein Degradation and InhibitorsRNA Interference and Gene Delivery

Cited by 1,199

How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., et al. (2018) · Nature Chemical Biology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 907

The cancer glycocalyx mechanically primes integrin-mediated growth and survival

Paszek, M. J., DuFort, C. C., Rossier, O., Bainer, R., Mouw, J. K., Godula, K., Hudak, J. E., Lakins, J. N., Wijekoon, A. C., Cassereau, L., et al. (2014) · Nature

Cell Adhesion Molecules ResearchGlycosylation and Glycoproteins Research

Cited by 699

Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones

Jewett, J. C., Sletten, E. M., & Bertozzi, C. R. (2010) · Journal of the American Chemical Society

Click Chemistry and ApplicationsBiotin and Related Studies

Cited by 697

Physiological blood–brain transport is impaired with age by a shift in transcytosis

Yang, A. C., Stevens, M. Y., Chen, M. B., Lee, D. P., Stähli, D., Gate, D., Contrepois, K., Chen, W., Iram, T., Zhang, L., et al. (2020) · Nature

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 477

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains

Pluvinage, J. V., Haney, M. S., Smith, B. A. H., Sun, J., Iram, T., Bonanno, L., Li, L., Lee, D. P., Morgens, D. W., Yang, A. C., et al. (2019) · Nature

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 459

d -Amino Acid Chemical Reporters Reveal Peptidoglycan Dynamics of an Intracellular Pathogen

Siegrist, M. S., Whiteside, S., Jewett, J. C., Aditham, A., Cava, F., & Bertozzi, C. R. (2013) · ACS Chemical Biology

Click Chemistry and ApplicationsBiochemical and Structural Characterization

Cited by 246

Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry

Swarts, B. M., Holsclaw, C. M., Jewett, J. C., Alber, M., Fox, D. M., Siegrist, M. S., Leary, J. A., Kalscheuer, R., & Bertozzi, C. R. (2012) · Journal of the American Chemical Society

Click Chemistry and ApplicationsTuberculosis Research and Epidemiology

Cited by 184

Subpolar addition of new cell wall is directed by DivIVA in mycobacteria

Meniche, X., Otten, R., Siegrist, M. S., Baer, C. E., Murphy, K. C., Bertozzi, C. R., & Sassetti, C. M. (2014) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 175

Membrane proteomics of phagosomes suggests a connection to autophagy

Shui, W., Sheu, L., Liu, J., Smart, B., Petzold, C. J., Hsieh, T.-Y., Pitcher, A., Keasling, J. D., & Bertozzi, C. R. (2008) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyPhagocytosis and Immune Regulation

Cited by 114

Deconvoluting the Functions of Polypeptide N-α-Acetylgalactosaminyltransferase Family Members by Glycopeptide Substrate Profiling

Pratt, M. R., Hang, H. C., Ten Hagen, K. G., Rarick, J., Gerken, T. A., Tabak, L. A., & Bertozzi, C. R. (2004) · Chemistry & Biology

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 98

Sequential assembly of the septal cell envelope prior to V snapping in Corynebacterium glutamicum

Zhou, X., Rodriguez-Rivera, F. P., Lim, H. C., Bell, J. C., Bernhardt, T. G., Bertozzi, C. R., & Theriot, J. A. (2019) · Nature Chemical Biology

Bacterial Genetics and BiotechnologyTuberculosis Research and Epidemiology

Cited by 61

Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE

Chongsaritsinsuk, J., Steigmeyer, A. D., Mahoney, K. E., Rosenfeld, M. A., Lucas, T. M., Smith, C. M., Li, A., Ince, D., Kearns, F. L., Battison, A. S., et al. (2023) · Nature Communications

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 52

Training the next generation of biomedical investigators in glycosciences

Agre, P., Bertozzi, C., Bissell, M., Campbell, K. P., Cummings, R. D., Desai, U. R., Estes, M., Flotte, T., Fogleman, G., Gage, F., et al. (2016) · Journal of Clinical Investigation

Glycosylation and Glycoproteins ResearchHealth and Medical Research Impacts

Cited by 34

Microglia Mediate Contact-Independent Neuronal Network Remodeling via Secreted Neuraminidase-3 Associated with Extracellular Vesicles

Delaveris, C. S., Wang, C. L., Riley, N. M., Li, S., Kulkarni, R. U., & Bertozzi, C. R. (2023) · ACS Central Science

Neuroinflammation and Neurodegeneration MechanismsGlycosylation and Glycoproteins Research

Cited by 25