Hesselink, Matthijs K.C.

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Timmers, S., Konings, E., Bilet, L., Houtkooper, R. H., van de Weijer, T., Goossens, G. H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S., et al. (2011) · Cell Metabolism

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 1,320

Oxidative Capacity, Lipotoxicity, and Mitochondrial Damage in Type 2 Diabetes

Schrauwen, P., & Hesselink, M. K. C. (2004) · Diabetes

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 408

Lower intrinsic ADP-stimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male type 2 diabetic patients

Phielix, E., Schrauwen-Hinderling, V. B., Mensink, M., Lenaers, E., Meex, R., Hoeks, J., Kooi, M. E., Moonen-Kornips, E., Sels, J.-P., Hesselink, M. K. C., et al. (2008) · Diabetes

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 359

Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

Meex, R. C. R., Schrauwen-Hinderling, V. B., Moonen-Kornips, E., Schaart, G., Mensink, M., Phielix, E., van de Weijer, T., Sels, J.-P., Schrauwen, P., & Hesselink, M. K. C. (2010) · Diabetes

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 355

Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects

Schrauwen-Hinderling, V. B., Kooi, M. E., Hesselink, M. K. C., Jeneson, J. A. L., Backes, W. H., van Echteld, C. J. A., van Engelshoven, J. M. A., Mensink, M., & Schrauwen, P. (2007) · Diabetologia

Diabetes, Cardiovascular Risks, and LipoproteinsAdipose Tissue and Metabolism

Cited by 304

Mitochondrial dysfunction and lipotoxicity

Schrauwen, P., Schrauwen-Hinderling, V., Hoeks, J., & Hesselink, M. K. C. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 268

Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

Hesselink, M. K. C., Schrauwen-Hinderling, V., & Schrauwen, P. (2016) · Nature Reviews Endocrinology

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 242

Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity

van Moorsel, D., Hansen, J., Havekes, B., Scheer, F. A. J. L., Jörgensen, J. A., Hoeks, J., Schrauwen-Hinderling, V. B., Duez, H., Lefebvre, P., Schaper, N. C., et al. (2016) · Molecular Metabolism

Circadian rhythm and melatoninAdipose Tissue and Metabolism

Cited by 218

Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes

Duvivier, B. M. F. M., Schaper, N. C., Hesselink, M. K. C., van Kan, L., Stienen, N., Winkens, B., Koster, A., & Savelberg, H. H. C. M. (2017) · Diabetologia

Physical Activity and HealthDiabetes Management and Research

Cited by 212

Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals

Phielix, E., Meex, R., Moonen-Kornips, E., Hesselink, M. K. C., & Schrauwen, P. (2010) · Diabetologia

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 206

Intramyocellular Lipid Content in Human Skeletal Muscle

Schrauwen‐Hinderling, V. B., Hesselink, M. K. C., Schrauwen, P., & Kooi, M. E. (2006) · Obesity

Muscle metabolism and nutritionAdipose Tissue and Metabolism

Cited by 202

An alternative function for human uncoupling protein 3: protection of mitochondria against accumulation of nonesterified fatty acids inside the mitochondrial matrix

SCHRAUWEN, P., SARIS, W. H. M., & HESSELINK, M. K. C. (2001) · The FASEB Journal

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 172

Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1α and PPARβ/δ gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus

Mensink, M., Hesselink, M. K. C., Russell, A. P., Schaart, G., Sels, J.-P., & Schrauwen, P. (2007) · International Journal of Obesity

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 160

Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance

Hoeks, J., van Herpen, N. A., Mensink, M., Moonen-Kornips, E., van Beurden, D., Hesselink, M. K. C., & Schrauwen, P. (2010) · Diabetes

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 156

Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise

Catoire, M., Alex, S., Paraskevopulos, N., Mattijssen, F., Evers-van Gogh, I., Schaart, G., Jeppesen, J., Kneppers, A., Mensink, M., Voshol, P. J., et al. (2014) · Proceedings of the National Academy of Sciences

Lipid metabolism and disordersPeroxisome Proliferator-Activated Receptors

Cited by 150

Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels

Bosma, M., Hesselink, M. K. C., Sparks, L. M., Timmers, S., Ferraz, M. J., Mattijssen, F., van Beurden, D., Schaart, G., de Baets, M. H., Verheyen, F. K., et al. (2012) · Diabetes

Lipid metabolism and biosynthesisAdipose Tissue and Metabolism

Cited by 149

Effect of training in the fasted state on metabolic responses during exercise with carbohydrate intake

De Bock, K., Derave, W., Eijnde, B. O., Hesselink, M. K., Koninckx, E., Rose, A. J., Schrauwen, P., Bonen, A., Richter, E. A., & Hespel, P. (2008) · Journal of Applied Physiology

Muscle metabolism and nutritionCardiovascular and exercise physiology

Cited by 144

Evidence for a Direct Effect of the NAD+ Precursor Acipimox on Muscle Mitochondrial Function in Humans

van de Weijer, T., Phielix, E., Bilet, L., Williams, E. G., Ropelle, E. R., Bierwagen, A., Livingstone, R., Nowotny, P., Sparks, L. M., Paglialunga, S., et al. (2015) · Diabetes

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 139

Effects of creatine loading and prolonged creatine supplementation on body composition, fuel selection, sprint and endurance performance in humans

LOON, L. J. C. V., OOSTERLAAR, A. M., HARTGENS, F., HESSELINK, M. K. C., SNOW, R. J., & WAGENMAKERS, A. J. M. (2003) · Clinical Science

Muscle metabolism and nutritionSports Performance and Training

Cited by 128

Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes

Sparks, L. M., Johannsen, N. M., Church, T. S., Earnest, C. P., Moonen-Kornips, E., Moro, C., Hesselink, M. K. C., Smith, S. R., & Schrauwen, P. (2013) · The Journal of Clinical Endocrinology & Metabolism

Cardiovascular and exercise physiologyAdipose Tissue and Metabolism

Cited by 123

Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes

Schrauwen, P., Hesselink, M. K. C., Blaak, E. E., Borghouts, L. B., Schaart, G., Saris, W. H. M., & Keizer, H. A. (2001) · Diabetes

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 112

Glucose ingestion during exercise blunts exercise-induced gene expression of skeletal muscle fat oxidative genes

Civitarese, A. E., Hesselink, M. K. C., Russell, A. P., Ravussin, E., & Schrauwen, P. (2005) · American Journal of Physiology-Endocrinology and Metabolism

Muscle metabolism and nutritionMetabolism, Diabetes, and Cancer

Cited by 99

High Oxidative Capacity Due to Chronic Exercise Training Attenuates Lipid-Induced Insulin Resistance

Phielix, E., Meex, R., Ouwens, D. M., Sparks, L., Hoeks, J., Schaart, G., Moonen-Kornips, E., Hesselink, M. K. C., & Schrauwen, P. (2012) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 99

Effects of exercise training on intrahepatic lipid content in humans

Brouwers, B., Hesselink, M. K. C., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2016) · Diabetologia

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 94