Mielke, Michelle M.

Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study

Jack, C. R., Therneau, T. M., Wiste, H. J., Weigand, S. D., Knopman, D. S., Lowe, V. J., Mielke, M. M., Vemuri, P., Roberts, R. O., Machulda, M. M., et al. (2016) · The Lancet Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 129

The association of psychotropic medication use with the cognitive, functional, and neuropsychiatric trajectory of Alzheimer's disease

Rosenberg, P. B., Mielke, M. M., Han, D., Leoutsakos, J. S., Lyketsos, C. G., Rabins, P. V., Zandi, P. P., Breitner, J. C. S., Norton, M. C., Welsh‐Bohmer, K. A., et al. (2012) · International Journal of Geriatric Psychiatry

Dementia and Cognitive Impairment ResearchPharmaceutical Practices and Patient Outcomes

Cited by 127

Longitudinal, region-specific course of diffusion tensor imaging measures in mild cognitive impairment and Alzheimer’s disease

Nowrangi, M. A., Lyketsos, C. G., Leoutsakos, J. S., Oishi, K., Albert, M., Mori, S., & Mielke, M. M. (2013) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAdvanced Neuroimaging Techniques and Applications

Cited by 120

Predicting future rates of tau accumulation on PET

Jack, C. R., Wiste, H. J., Weigand, S. D., Therneau, T. M., Lowe, V. J., Knopman, D. S., Botha, H., Graff-Radford, J., Jones, D. T., Ferman, T. J., et al. (2020) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 117

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults

Lowe, V. J., Bruinsma, T. J., Wiste, H. J., Min, H.-K., Weigand, S. D., Fang, P., Senjem, M. L., Therneau, T. M., Boeve, B. F., Josephs, K. A., et al. (2019) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 107

Association of plasma biomarkers of Alzheimer disease with cognition and medical comorbidities in a biracial cohort

Ramanan, V. K., Graff-Radford, J., Syrjanen, J., Shir, D., Algeciras-Schimnich, A., Lucas, J., Martens, Y. A., Carrasquillo, M. M., Day, G. S., Ertekin-Taner, N., et al. (2023) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 89

Diffusion models reveal white matter microstructural changes with ageing, pathology and cognition

Raghavan, S., Reid, R. I., Przybelski, S. A., Lesnick, T. G., Graff-Radford, J., Schwarz, C. G., Knopman, D. S., Mielke, M. M., Machulda, M. M., Petersen, R. C., et al. (2021) · Brain Communications

Advanced Neuroimaging Techniques and ApplicationsDementia and Cognitive Impairment Research

Cited by 79

The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals

Wennberg, A. M., Whitwell, J. L., Tosakulwong, N., Weigand, S. D., Murray, M. E., Machulda, M. M., Petrucelli, L., Mielke, M. M., Jack, C. R., Knopman, D. S., et al. (2019) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 79

Diffusion tensor imaging of neuropsychiatric symptoms in mild cognitive impairment and Alzheimer's dementia

Tighe, S. K., Oishi, K., Mori, S., Smith, G. S., Albert, M., Lyketsos, C. G., & Mielke, M. M. (2012) · The Journal of Neuropsychiatry and Clinical Neurosciences

Dementia and Cognitive Impairment ResearchAdvanced Neuroimaging Techniques and Applications

Cited by 77

Associations between biomarkers of cellular senescence and physical function in humans: observations from the lifestyle interventions for elders (LIFE) study

Fielding, R. A., Atkinson, E. J., Aversa, Z., White, T. A., Heeren, A. A., Achenbach, S. J., Mielke, M. M., Cummings, S. R., Pahor, M., Leeuwenburgh, C., et al. (2022) · GeroScience

Telomeres, Telomerase, and SenescenceNutrition and Health in Aging

Cited by 75

Sex differences in longitudinal tau-PET in preclinical Alzheimer disease: a meta-analysis

Coughlan, G. T., Klinger, H. M., Boyle, R., Betthauser, T. J., Binette, A. P., Christenson, L., Chadwick, T., Hansson, O., Harrison, T. M., Healy, B., et al. (2025) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 69

Selective Worsening of Brain Injury Biomarker Abnormalities in Cognitively Normal Elderly Persons With β-Amyloidosis

Knopman, D. S., Jack, C. R., Wiste, H. J., Weigand, S. D., Vemuri, P., Lowe, V. J., Kantarci, K., Gunter, J. L., Senjem, M. L., Mielke, M. M., et al. (2013) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 68

Sex and gender in Alzheimer's disease – Does it matter?

Mielke, M. M., Ferretti, M. T., Iulita, M. F., Hayden, K., & Khachaturian, A. S. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchSex and Gender in Healthcare

Cited by 67

Association of Initial β-Amyloid Levels With Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive Impairment

Knopman, D. S., Lundt, E. S., Therneau, T. M., Albertson, S. M., Gunter, J. L., Senjem, M. L., Schwarz, C. G., Mielke, M. M., Machulda, M. M., Boeve, B. F., et al. (2021) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 61

A lipid storage–like disorder contributes to cognitive decline in HIV-infected subjects

Bandaru, V. V. R., Mielke, M. M., Sacktor, N., McArthur, J. C., Grant, I., Letendre, S., Chang, L., Wojna, V., Pardo, C., Calabresi, P., et al. (2013) · Neurology

HIV Research and TreatmentHIV-related health complications and treatments

Cited by 61

Comparison of CSF phosphorylated tau 181 and 217 for cognitive decline

Mielke, M. M., Aakre, J. A., Algeciras‐Schimnich, A., Proctor, N. K., Machulda, M. M., Eichenlaub, U., Knopman, D. S., Vemuri, P., Graff‐Radford, J., Jack, C. R., et al. (2022) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 55

Leisure-time physical activity and the risk of incident dementia: the mayo clinic study of aging

Krell-Roesch, J., Feder, N. T., Roberts, R. O., Mielke, M. M., Christianson, T. J., Knopman, D. S., Petersen, R. C., & Geda, Y. E. (2018) · Journal of Alzheimer s Disease

Dementia and Cognitive Impairment ResearchPhysical Activity and Health

Cited by 50

Resilience and brain health in global populations

Udeh-Momoh, C. T., Migeot, J., Blackmon, K., Mielke, M. M., Melloni, M., Cox, L., Yaffe, K., Santamaria-Garcia, H., Stern, Y., & Ibanez, A. (2025) · Nature Medicine

Resilience and Mental HealthHealth, psychology, and well-being

Cited by 42

Association of Hospitalization with Long‐Term Cognitive Trajectories in Older Adults

Sprung, J., Knopman, D. S., Petersen, R. C., Mielke, M. M., Weingarten, T. N., Vassilaki, M., Martin, D. P., Schulte, P. J., Hanson, A. C., Schroeder, D. R., et al. (2021) · Journal of the American Geriatrics Society

Dementia and Cognitive Impairment ResearchIntensive Care Unit Cognitive Disorders

Cited by 39

Biomarkers of cellular senescence predict the onset of mobility disability and are reduced by physical activity in older adults

Fielding, R. A., Atkinson, E. J., Aversa, Z., White, T. A., Heeren, A. A., Mielke, M. M., Cummings, S. R., Pahor, M., Leeuwenburgh, C., & LeBrasseur, N. K. (2024) · The Journals of Gerontology: Series A

Telomeres, Telomerase, and SenescenceFrailty in Older Adults

Cited by 38

Timeline of Rapid Eye Movement Sleep Behavior Disorder in Overt Alpha‐Synucleinopathies

Stang, C. D., Mullan, A. F., Hajeb, M., Camerucci, E., Turcano, P., Martin, P., Mielke, M. M., Josephs, K. A., Bower, J. H., St Louis, E. K., et al. (2021) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsSleep and related disorders

Cited by 29

Genetic risk scores enhance the diagnostic value of plasma biomarkers of brain amyloidosis

Ramanan, V. K., Gebre, R. K., Graff-Radford, J., Hofrenning, E., Algeciras-Schimnich, A., Figdore, D. J., Lowe, V. J., Mielke, M. M., Knopman, D. S., Ross, O. A., et al. (2023) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 24

Aging: What We Can Learn From Elephants

Chusyd, D. E., Ackermans, N. L., Austad, S. N., Hof, P. R., Mielke, M. M., Sherwood, C. C., & Allison, D. B. (2021) · Frontiers in Aging

Genetics, Aging, and Longevity in Model OrganismsAging and Gerontology Research

Cited by 23

Sex and gender considerations in dementia: a call for global research

Vila-Castelar, C., Udeh-Momoh, C., Aggarwal, N. T., & Mielke, M. M. (2023) · Nature Aging

Dementia and Cognitive Impairment ResearchSex and Gender in Healthcare

Cited by 21