Johnson, Keith A.

Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis

Zhou, X., Chen, Y., Mok, K. Y., Zhao, Q., Chen, K., Chen, Y., Hardy, J., Li, Y., Fu, A. K. Y., Guo, Q., et al. (2018) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 96

Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia

Sepulveda-Falla, D., Sanchez, J. S., Almeida, M. C., Boassa, D., Acosta-Uribe, J., Vila-Castelar, C., Ramirez-Gomez, L., Baena, A., Aguillon, D., Villalba-Moreno, N. D., et al. (2022) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 92

Plasma IL-12/IFN-γ axis predicts cognitive trajectories in cognitively unimpaired older adults

Yang, H., Zhang, C., Carlyle, B. C., Zhen, S. Y., Trombetta, B. A., Schultz, A. P., Pruzin, J. J., Fitzpatrick, C. D., Yau, W. W., Kirn, D. R., et al. (2022) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 90

APOE effects on regional tau in preclinical Alzheimer’s disease

Young, C. B., Johns, E., Kennedy, G., Belloy, M. E., Insel, P. S., Greicius, M. D., Sperling, R. A., Johnson, K. A., Poston, K. L., Mormino, E. C., et al. (2023) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 80

Amyloid‐associated increases in longitudinal report of subjective cognitive complaints

Amariglio, R. E., Buckley, R. F., Mormino, E. C., Marshall, G. A., Johnson, K. A., Rentz, D. M., & Sperling, R. A. (2018) · Alzheimer's & Dementia: Translational Research & Clinical Interventions

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 80

Divergent Cortical Tau Positron Emission Tomography Patterns Among Patients With Preclinical Alzheimer Disease

Young, C. B., Winer, J. R., Younes, K., Cody, K. A., Betthauser, T. J., Johnson, S. C., Schultz, A., Sperling, R. A., Greicius, M. D., Cobos, I., et al. (2022) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 79

Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex

Sepulcre, J., Grothe, M. J., Sabuncu, M., Chhatwal, J., Schultz, A. P., Hanseeuw, B., El Fakhri, G., Sperling, R., & Johnson, K. A. (2017) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 73

Apathy is associated with increased amyloid burden in mild cognitive impairment

Marshall, G. A., Donovan, N. J., Lorius, N., Gidicsin, C. M., Maye, J., Pepin, L. C., Becker, J. A., Amariglio, R. E., Rentz, D. M., Sperling, R. A., et al. (2013) · The Journal of Neuropsychiatry and Clinical Neurosciences

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 73

Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

Chen, S.-D., Lu, J.-Y., Li, H.-Q., Yang, Y.-X., Jiang, J.-H., Cui, M., Zuo, C.-T., Tan, L., Dong, Q., Yu, J.-T., et al. (2021) · Translational Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 71

Sex differences in longitudinal tau-PET in preclinical Alzheimer disease: a meta-analysis

Coughlan, G. T., Klinger, H. M., Boyle, R., Betthauser, T. J., Binette, A. P., Christenson, L., Chadwick, T., Hansson, O., Harrison, T. M., Healy, B., et al. (2025) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 69

APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer’s Disease

Quiroz, Y. T., Aguillon, D., Aguirre-Acevedo, D. C., Vasquez, D., Zuluaga, Y., Baena, A. Y., Madrigal, L., Hincapié, L., Sanchez, J. S., Langella, S., et al. (2024) · New England Journal of Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

Estimating Total Cerebral Microinfarct Burden From Diffusion-Weighted Imaging

Auriel, E., Westover, M. B., Bianchi, M. T., Reijmer, Y., Martinez-Ramirez, S., Ni, J., Van Etten, E., Frosch, M. P., Fotiadis, P., Schwab, K., et al. (2015) · Stroke

Intracerebral and Subarachnoid Hemorrhage ResearchCerebrovascular and genetic disorders

Cited by 61

Association of anxiety with subcortical amyloidosis in cognitively normal older adults

Hanseeuw, B. J., Jonas, V., Jackson, J., Betensky, R. A., Rentz, D. M., Johnson, K. A., Sperling, R. A., & Donovan, N. J. (2020) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 61

Hippocampal hypometabolism in older adults with memory complaints and increased amyloid burden

Vannini, P., Hanseeuw, B., Munro, C. E., Amariglio, R. E., Marshall, G. A., Rentz, D. M., Pascual-Leone, A., Johnson, K. A., & Sperling, R. A. (2017) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 61

Apathy is associated with lower inferior temporal cortical thickness in mild cognitive impairment and normal elderly individuals

Guercio, B. J., Donovan, N. J., Ward, A., Schultz, A., Lorius, N., Amariglio, R. E., Rentz, D. M., Johnson, K. A., Sperling, R. A., & Marshall, G. A. (2015) · The Journal of Neuropsychiatry and Clinical Neurosciences

Dementia and Cognitive Impairment ResearchCancer-related cognitive impairment studies

Cited by 61

Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals

Chhatwal, J. P., Schultz, A. P., Dang, Y., Ostaszewski, B., Liu, L., Yang, H.-S., Johnson, K. A., Sperling, R. A., & Selkoe, D. J. (2020) · Nature Communications

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 60

Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer’s disease: findings from the Colombia-Boston (COLBOS) biomarker study

Sanchez, J. S., Hanseeuw, B. J., Lopera, F., Sperling, R. A., Baena, A., Bocanegra, Y., Aguillon, D., Guzmán-Vélez, E., Pardilla-Delgado, E., Ramirez-Gomez, L., et al. (2021) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 58

KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease

Neitzel, J., Franzmeier, N., Rubinski, A., Dichgans, M., Brendel, M., (ADNI), A. D. N. I., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., et al. (2021) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 57

Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer’s Disease: Results from the DIAN Study Group

Su, Y., Blazey, T. M., Owen, C. J., Christensen, J. J., Friedrichsen, K., Joseph-Mathurin, N., Wang, Q., Hornbeck, R. C., Ances, B. M., Snyder, A. Z., et al. (2016) · PLOS ONE

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 56

Aggregated Tau Measured by Visual Interpretation of Flortaucipir Positron Emission Tomography and the Associated Risk of Clinical Progression of Mild Cognitive Impairment and Alzheimer Disease: Results From 2 Phase III Clinical Trials

Lu, M., Pontecorvo, M. J., Devous, M. D., Arora, A. K., Galante, N., McGeehan, A., Devadanam, C., Salloway, S. P., Doraiswamy, P. M., Curtis, C., et al. (2021) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 56

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer’s disease

Huang, M., Yang, W., Feng, Q., Chen, W., Initiative, T. A. D. N., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., et al. (2017) · Scientific Reports

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 55

Plasma p‐tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease

Aguillon, D., Langella, S., Chen, Y., Sanchez, J. S., Su, Y., Vila‐Castelar, C., Vasquez, D., Zetterberg, H., Hansson, O., Dage, J. L., et al. (2023) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 54

Cued memory decline in biomarker-defined preclinical Alzheimer disease

Papp, K. V., Rentz, D. M., Mormino, E. C., Schultz, A. P., Amariglio, R. E., Quiroz, Y., Johnson, K. A., & Sperling, R. A. (2017) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 52

Network Tau spreading is vulnerable to the expression gradients of APOE and glutamatergic-related genes

Montal, V., Diez, I., Kim, C.-M., Orwig, W., Bueichekú, E., Gutiérrez-Zúñiga, R., Bejanin, A., Pegueroles, J., Dols-Icardo, O., Vannini, P., et al. (2022) · Science Translational Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 52