Südhof, Thomas C.

SV2 Renders Primed Synaptic Vesicles Competent for Ca2+-Induced Exocytosis

Chang, W.-P., & Südhof, T. C. (2009) · The Journal of Neuroscience

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 176

Spatial transcriptomics reveal neuron–astrocyte synergy in long-term memory

Sun, W., Liu, Z., Jiang, X., Chen, M. B., Dong, H., Liu, J., Südhof, T. C., & Quake, S. R. (2024) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 165

Continuous and Discrete Neuron Types of the Adult Murine Striatum

Stanley, G., Gokce, O., Malenka, R. C., Südhof, T. C., & Quake, S. R. (2020) · Neuron

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 158

Augmenting neurotransmitter release by enhancing the apparent Ca 2+ affinity of synaptotagmin 1

Rhee, J.-S., Li, L. Y., Shin, O.-H., Rah, J.-C., Rizo, J., Südhof, T. C., & Rosenmund, C. (2005) · Proceedings of the National Academy of Sciences

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 155

Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk

Huang, Y.-W. A., Zhou, B., Nabet, A. M., Wernig, M., & Südhof, T. C. (2019) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 152

Presynaptic neuronal pentraxin receptor organizes excitatory and inhibitory synapses

Lee, S.-J., Wei, M., Zhang, C., Maxeiner, S., Pak, C., Calado Botelho, S., Trotter, J., Sterky, F. H., & Südhof, T. C. (2017) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchBiomarkers in Disease Mechanisms

Cited by 146

A molecular pathway of neurodegeneration linking α-synuclein to ApoE and Aβ peptides

Gallardo, G., Schlüter, O. M., & Südhof, T. C. (2008) · Nature Neuroscience

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 145

The Presynaptic Active Zone Protein RIM1α Is Critical for Normal Learning and Memory

Powell, C. M., Schoch, S., Monteggia, L., Barrot, M., Matos, M. F., Feldmann, N., Südhof, T. C., & Nestler, E. J. (2004) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 143

Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution

Brewer, K. D., Bacaj, T., Cavalli, A., Camilloni, C., Swarbrick, J. D., Liu, J., Zhou, A., Zhou, P., Barlow, N., Xu, J., et al. (2015) · Nature Structural & Molecular Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 142

An autism‐associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor‐mediated synaptic transmission in hippocampus

Etherton, M. R., Tabuchi, K., Sharma, M., Ko, J., & Südhof, T. C. (2011) · The EMBO Journal

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 140

Postsynaptic Complexin Controls AMPA Receptor Exocytosis during LTP

Ahmad, M., Polepalli, J. S., Goswami, D., Yang, X., Kaeser-Woo, Y. J., Südhof, T. C., & Malenka, R. C. (2012) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 133

Structural Basis for a Munc13–1 Homodimer to Munc13–1/RIM Heterodimer Switch

Lu, J., Machius, M., Dulubova, I., Dai, H., Südhof, T. C., Tomchick, D. R., & Rizo, J. (2006) · PLoS Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 132

CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein

Tabuchi, K., Biederer, T., Butz, S., & Südhof, T. C. (2002) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 131

RIM genes differentially contribute to organizing presynaptic release sites

Kaeser, P. S., Deng, L., Fan, M., & Südhof, T. C. (2012) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 115

Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment

Gan, K. J., & Südhof, T. C. (2019) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 114

Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release

Zhou, P., Bacaj, T., Yang, X., Pang, Z. P., & Südhof, T. C. (2013) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 114

A Gain-of-Function Mutation in Synaptotagmin-1 Reveals a Critical Role of Ca 2+ -Dependent Soluble N -Ethylmaleimide-Sensitive Factor Attachment Protein Receptor Complex Binding in Synaptic Exocytosis

Pang, Z. P., Shin, O.-H., Meyer, A. C., Rosenmund, C., & Südhof, T. C. (2006) · The Journal of Neuroscience

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 113

Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins☆☆Sequence data from this article have been deposited with the GenBank Data Library under Accession Nos. AF548738 and AF548739.

Wang, Y., & Südhof, T. C. (2003) · Genomics

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 112

Persistent transcriptional programmes are associated with remote memory

Chen, M. B., Jiang, X., Quake, S. R., & Südhof, T. C. (2020) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 111

ELKS2α/CAST deletion selectively increases neurotransmitter release at inhibitory synapses

Kaeser, P. S., Deng, L., Chávez, A. E., Liu, X., Castillo, P. E., & Südhof, T. C. (2009) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 102

Synaptotagmin‐7 is a principal Ca2+ sensor for Ca2+‐induced glucagon exocytosis in pancreas

Gustavsson, N., Wei, S., Hoang, D. N., Lao, Y., Zhang, Q., Radda, G. K., Rorsman, P., Südhof, T. C., & Han, W. (2009) · The Journal of Physiology

Cellular transport and secretionPancreatic function and diabetes

Cited by 100

Deletion of α‐neurexins does not cause a major impairment of axonal pathfinding or synapse formation

Dudanova, I., Tabuchi, K., Rohlmann, A., Südhof, T. C., & Missler, M. (2007) · Journal of Comparative Neurology

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 98

Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning

Tsetsenis, T., Younts, T. J., Chiu, C. Q., Kaeser, P. S., Castillo, P. E., & Südhof, T. C. (2011) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 81

Synaptotagmin-7 phosphorylation mediates GLP-1–dependent potentiation of insulin secretion from β-cells

Wu, B., Wei, S., Petersen, N., Ali, Y., Wang, X., Bacaj, T., Rorsman, P., Hong, W., Südhof, T. C., & Han, W. (2015) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesCellular transport and secretion

Cited by 76