Südhof, Thomas C.

Structure and Evolution of Neurexin Genes: Insight into the Mechanism of Alternative Splicing

Tabuchi, K., & Südhof, T. C. (2002) · Genomics

RNA Research and SplicingNeuroscience and Neuropharmacology Research

Cited by 305

Purification of component A of Rab geranylgeranyl transferase: possible identity with the choroideremia gene product

Seabra, M. C., Brown, M. S., Slaughter, C. A., Südhof, T. C., & Goldstein, J. L. (1992) · Cell

Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling

Cited by 300

A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?

Dulubova, I., Lou, X., Lu, J., Huryeva, I., Alam, A., Schneggenburger, R., Südhof, T. C., & Rizo, J. (2005) · The EMBO Journal

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 289

RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13

Deng, L., Kaeser, P. S., Xu, W., & Südhof, T. C. (2011) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 287

Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling

Földy, C., Malenka, R. C., & Südhof, T. C. (2013) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 287

Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release

Xu, J., Pang, Z. P., Shin, O.-H., & Südhof, T. C. (2009) · Nature Neuroscience

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 274

CASK Functions as a Mg2+-independent neurexin kinase

Mukherjee, K., Sharma, M., Urlaub, H., Bourenkov, G. P., Jahn, R., Südhof, T. C., & Wahl, M. C. (2008) · Cell

Protein Kinase Regulation and GTPase SignalingNeuroscience and Neuropharmacology Research

Cited by 271

Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release

McMahon, H. T., Bolshakov, V. Y., Janz, R., Hammer, R. E., Siegelbaum, S. A., & Südhof, T. C. (1996) · Proceedings of the National Academy of Sciences

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 262

Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1α

Chevaleyre, V., Heifets, B. D., Kaeser, P. S., Südhof, T. C., & Castillo, P. E. (2007) · Neuron

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 261

A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones

Wang, Y., Liu, X., Biederer, T., & Südhof, T. C. (2002) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 256

Close membrane-membrane proximity induced by Ca2+-dependent multivalent binding of synaptotagmin-1 to phospholipids

Araç, D., Chen, X., Khant, H. A., Ubach, J., Ludtke, S. J., Kikkawa, M., Johnson, A. E., Chiu, W., Südhof, T. C., & Rizo, J. (2006) · Nature Structural & Molecular Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 256

The RIM/NIM Family of Neuronal C2 Domain Proteins

Wang, Y., Sugita, S., & Südhof, T. C. (2000) · Journal of Biological Chemistry

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 243

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

Shin, O.-H., Lu, J., Rhee, J.-S., Tomchick, D. R., Pang, Z. P., Wojcik, S. M., Camacho-Perez, M., Brose, N., Machius, M., Rizo, J., et al. (2010) · Nature Structural & Molecular Biology

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 243

Autonomous Function of Synaptotagmin 1 in Triggering Synchronous Release Independent of Asynchronous Release

Maximov, A., & Südhof, T. C. (2005) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 238

LTP Requires a Unique Postsynaptic SNARE Fusion Machinery

Jurado, S., Goswami, D., Zhang, Y., Molina, A. J. M., Südhof, T. C., & Malenka, R. C. (2013) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 232

Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates

Mall, M., Kareta, M. S., Chanda, S., Ahlenius, H., Perotti, N., Zhou, B., Grieder, S. D., Ge, X., Drake, S., Euong Ang, C., et al. (2017) · Nature

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 225

Binding of F-spondin to amyloid-β precursor protein: a candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage

Ho, A., & Südhof, T. C. (2004) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 224

Deletion of CASK in mice is lethal and impairs synaptic function

Atasoy, D., Schoch, S., Ho, A., Nadasy, K. A., Liu, X., Zhang, W., Mukherjee, K., Nosyreva, E. D., Fernandez-Chacon, R., Missler, M., et al. (2007) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 212

Understanding Synapses: Past, Present, and Future

Südhof, T. C., & Malenka, R. C. (2008) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 207

Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity

Schlüter, O. M., Basu, J., Südhof, T. C., & Rosenmund, C. (2006) · The Journal of Neuroscience

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 199

Postsynaptic synaptotagmins mediate AMPA receptor exocytosis during LTP

Wu, D., Bacaj, T., Morishita, W., Goswami, D., Arendt, K. L., Xu, W., Chen, L., Malenka, R. C., & Südhof, T. C. (2017) · Nature

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 195

Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis

Mukherjee, K., Yang, X., Gerber, S. H., Kwon, H.-B., Ho, A., Castillo, P. E., Liu, X., & Südhof, T. C. (2010) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 195

The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins

Bolliger, M. F., Martinelli, D. C., & Südhof, T. C. (2011) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 189

Single-cell RNAseq reveals cell adhesion molecule profiles in electrophysiologically defined neurons

Földy, C., Darmanis, S., Aoto, J., Malenka, R. C., Quake, S. R., & Südhof, T. C. (2016) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchSingle-cell and spatial transcriptomics

Cited by 179