Simell, Tuula

Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children

Ziegler, A. G., Rewers, M., Simell, O., Simell, T., Lempainen, J., Steck, A., Winkler, C., Ilonen, J., Veijola, R., Knip, M., et al. (2013) · JAMA

Diabetes and associated disordersDiabetes Management and Research

Cited by 1,312

Toward defining the autoimmune microbiome for type 1 diabetes

Giongo, A., Gano, K. A., Crabb, D. B., Mukherjee, N., Novelo, L. L., Casella, G., Drew, J. C., Ilonen, J., Knip, M., Hyöty, H., et al. (2011) · The ISME Journal

Gut microbiota and healthDiabetes and associated disorders

Cited by 806

Gut Microbiome Metagenomics Analysis Suggests a Functional Model for the Development of Autoimmunity for Type 1 Diabetes

Brown, C. T., Davis-Richardson, A. G., Giongo, A., Gano, K. A., Crabb, D. B., Mukherjee, N., Casella, G., Drew, J. C., Ilonen, J., Knip, M., et al. (2011) · PLoS ONE

Gut microbiota and healthDiabetes and associated disorders

Cited by 778

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

Orešič, M., Simell, S., Sysi-Aho, M., Näntö-Salonen, K., Seppänen-Laakso, T., Parikka, V., Katajamaa, M., Hekkala, A., Mattila, I., Keskinen, P., et al. (2008) · The Journal of Experimental Medicine

Diabetes and associated disordersMetabolomics and Mass Spectrometry Studies

Cited by 449

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial

Näntö-Salonen, K., Kupila, A., Simell, S., Siljander, H., Salonsaari, T., Hekkala, A., Korhonen, S., Erkkola, R., Sipilä, J. I., Haavisto, L., et al. (2008) · The Lancet

Diabetes and associated disordersDiabetes Management and Research

Cited by 382

Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk

Parikka, V., Näntö-Salonen, K., Saarinen, M., Simell, T., Ilonen, J., Hyöty, H., Veijola, R., Knip, M., & Simell, O. (2012) · Diabetologia

Diabetes and associated disordersDiabetes Management and Research

Cited by 235

Natural History of β-Cell Autoimmunity in Young Children with Increased Genetic Susceptibility to Type 1 Diabetes Recruited from the General Population

Kimpimäki, T., Kulmala, P., Savola, K., Kupila, A., Korhonen, S., Simell, T., Ilonen, J., Simell, O., & Knip, M. (2002) · The Journal of Clinical Endocrinology & Metabolism

Diabetes and associated disordersDiabetes Management and Research

Cited by 146

Dynamics of Diabetes-Associated Autoantibodies in Young Children with Human Leukocyte Antigen-Conferred Risk of Type 1 Diabetes Recruited from the General Population

Kukko, M., Kimpimäki, T., Korhonen, S., Kupila, A., Simell, S., Veijola, R., Simell, T., Ilonen, J., Simell, O., & Knip, M. (2005) · The Journal of Clinical Endocrinology & Metabolism

Diabetes and associated disordersDiabetes Management and Research

Cited by 116

Intranasally administered insulin intended for prevention of type 1 diabetes—a safety study in healthy adults

Kupila, A., Sipilä, J., Keskinen, P., Simell, T., Knip, M., Pulkki, K., & Simell, O. (2003) · Diabetes/Metabolism Research and Reviews

Diabetes and associated disordersDiabetes Management and Research

Cited by 64

Role of insulin autoantibody affinity as a predictive marker for type 1 diabetes in young children with HLA-conferred disease susceptibility

Siljander, H., Härkönen, T., Hermann, R., Simell, S., Hekkala, A., Salonsaari, R., Simell, T., Simell, O., Ilonen, J., Veijola, R., et al. (2009) · Diabetes/Metabolism Research and Reviews

Diabetes and associated disordersDiabetes Management and Research

Cited by 30