Most cited biochemistry, genetics and molecular biology papers
- Verified
The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II
Elmlund, H., Baraznenok, V., Lindahl, M., Samuelsen, C. O., Koeck, P. J. B., Holmberg, S., Hebert, H., & Gustafsson, C. M. (2006) · Proceedings of the National Academy of Sciences
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 230
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Expression of the Hevea brasiliensis (H.B.K.) Mull. Arg. 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase 1 in Tobacco Results in Sterol Overproduction
Schaller, H., Grausem, B., Benveniste, P., Chye, M. L., Tan, C. T., Song, Y. H., & Chua, N. H. (1995) · Plant Physiology
Plant biochemistry and biosynthesisLipid metabolism and biosynthesis
Cited by 230
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Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism
Weivoda, M. M., Chew, C. K., Monroe, D. G., Farr, J. N., Atkinson, E. J., Geske, J. R., Eckhardt, B., Thicke, B., Ruan, M., Tweed, A. J., et al. (2020) · Nature Communications
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 230
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Tip60: Connecting chromatin to DNA damage signaling
Sun, Y., Jiang, X., & Price, B. D. (2010) · Cell Cycle
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 230
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Detection and Clearance of Damaged Lysosomes by the Endo-Lysosomal Damage Response and Lysophagy
Papadopoulos, C., & Meyer, H. (2017) · Current Biology
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 230
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A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function
Araya, C. L., Fowler, D. M., Chen, W., Muniez, I., Kelly, J. W., & Fields, S. (2012) · Proceedings of the National Academy of Sciences
Protein Structure and Dynamicsthermodynamics and calorimetric analyses
Cited by 230
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Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome
Osterweil, E. K., Chuang, S.-C., Chubykin, A. A., Sidorov, M., Bianchi, R., Wong, R. K. S., & Bear, M. F. (2013) · Neuron
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 230
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Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer’s type (SDAT)
Ishrat, T., Hoda, M. N., Khan, M. B., Yousuf, S., Ahmad, M., Khan, M. M., Ahmad, A., & Islam, F. (2009) · European Neuropsychopharmacology
Curcumin's Biomedical ApplicationsAlzheimer's disease research and treatments
Cited by 230
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Oxidative Stress Causes Heart Failure with Impaired Mitochondrial Respiration
Nojiri, H., Shimizu, T., Funakoshi, M., Yamaguchi, O., Zhou, H., Kawakami, S., Ohta, Y., Sami, M., Tachibana, T., Ishikawa, H., et al. (2006) · Journal of Biological Chemistry
Mitochondrial Function and PathologyNitric Oxide and Endothelin Effects
Cited by 230
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Adolescent nicotine exposure causes persistent upregulation of nicotinic cholinergic receptors in rat brain regions
Trauth, J. A., Seidler, F. J., McCook, E. C., & Slotkin, T. A. (1999) · Brain Research
Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation
Cited by 230
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Some new aspects of creatine kinase (CK): compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology
Wallimann, T., Dolder, M., Schlattner, U., Eder, M., Hornemann, T., O'Gorman, E., Rück, A., & Brdiczka, D. (1998) · BioFactors
Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer
Cited by 230
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Southern blotting
Southern, E. (2006) · Nature Protocols
Molecular Biology Techniques and ApplicationsDNA and Nucleic Acid Chemistry
Cited by 230
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NADP + Reduction with Reduced Ferredoxin and NADP + Reduction with NADH Are Coupled via an Electron-Bifurcating Enzyme Complex in Clostridium kluyveri
Wang, S., Huang, H., Moll, J., & Thauer, R. K. (2010) · Journal of Bacteriology
Metalloenzymes and iron-sulfur proteinsMicrobial metabolism and enzyme function
Cited by 230
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Synaptic regulation of translation of dendritic mRNAs
Schuman, E. M., Dynes, J. L., & Steward, O. (2006) · The Journal of Neuroscience
RNA and protein synthesis mechanismsNeuroscience and Neuropharmacology Research
Cited by 230
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Open-Channel Block by the Cytoplasmic Tail of Sodium Channel β4 as a Mechanism for Resurgent Sodium Current
Grieco, T. M., Malhotra, J. D., Chen, C., Isom, L. L., & Raman, I. M. (2005) · Neuron
Ion channel regulation and functionCardiac electrophysiology and arrhythmias
Cited by 230
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High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects
Tong, H., Huang, J., Xiao, Q., He, B., Dong, X., Liu, Y., Yang, X., Han, D., Wang, Z., Wang, X., et al. (2023) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 230
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A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3
Tajan, M., Hock, A. K., Blagih, J., Robertson, N. A., Labuschagne, C. F., Kruiswijk, F., Humpton, T. J., Adams, P. D., & Vousden, K. H. (2018) · Cell Metabolism
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism
Cited by 230
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Elevated leukocyte cyclic AMP—phosphodiesterase in atopic disease: a possible mechanism for cyclic AMP—agonist hyporesponsiveness
Grewe, S. R., Chan, S. C., & Hanifin, J. M. (1982) · Journal of Allergy and Clinical Immunology
Phosphodiesterase function and regulationAsthma and respiratory diseases
Cited by 230
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Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial
Bjarnadottir, O., Romero, Q., Bendahl, P.-O., Jirström, K., Rydén, L., Loman, N., Uhlén, M., Johannesson, H., Rose, C., Grabau, D., et al. (2013) · Breast Cancer Research and Treatment
Cancer, Lipids, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 230
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Permeability barrier dysfunction in transgenic mice overexpressing claudin 6
Turksen, K., & Troy, T.-C. (2002) · Development
Skin and Cellular Biology ResearchBarrier Structure and Function Studies
Cited by 230
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Locus control regions of mammalian β-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights
Hardison, R., Slightom, J. L., Gumucio, D. L., Goodman, M., Stojanovic, N., & Miller, W. (1997) · Gene
Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders
Cited by 230
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Overall survival with [177Lu]Lu-PSMA-617 versus cabazitaxel in metastatic castration-resistant prostate cancer (TheraP): secondary outcomes of a randomised, open-label, phase 2 trial
Hofman, M. S., Emmett, L., Sandhu, S., Iravani, A., Buteau, J. P., Joshua, A. M., Goh, J. C., Pattison, D. A., Tan, T. H., Kirkwood, I. D., et al. (2024) · The Lancet Oncology
Prostate Cancer Treatment and ResearchRadiopharmaceutical Chemistry and Applications
Cited by 230
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miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels
Abdelmohsen, K., Srikantan, S., Kuwano, Y., & Gorospe, M. (2008) · Proceedings of the National Academy of Sciences
MicroRNA in disease regulationRNA Research and Splicing
Cited by 230
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Gene Therapy for Leber Hereditary Optic Neuropathy
Feuer, W. J., Schiffman, J. C., Davis, J. L., Porciatti, V., Gonzalez, P., Koilkonda, R. D., Yuan, H., Lalwani, A., Lam, B. L., & Guy, J. (2016) · Ophthalmology
Virus-based gene therapy researchRetinal Development and Disorders
Cited by 230
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