Most cited biochemistry, genetics and molecular biology papers
- Verified
HSP90AB1: Helping the good and the bad
Haase, M., & Fitze, G. (2016) · Gene
Heat shock proteins researchUbiquitin and proteasome pathways
Cited by 179
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Proteasomes are regulated by interferon gamma: implications for antigen processing
Yang, Y., Waters, J. B., Früh, K., & Peterson, P. A. (1992) · Proceedings of the National Academy of Sciences
Ubiquitin and proteasome pathwaysProtease and Inhibitor Mechanisms
Cited by 179
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Association of type 2 diabetes mellitus and the risk of colorectal cancer: A meta-analysis and systematic review
Guraya, S. Y. (2015) · World Journal of Gastroenterology
Metabolism, Diabetes, and CancerCancer Risks and Factors
Cited by 179
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Templates are available to model nearly all complexes of structurally characterized proteins
Kundrotas, P. J., Zhu, Z., Janin, J., & Vakser, I. A. (2012) · Proceedings of the National Academy of Sciences
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 179
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Late local recurrences in a randomised trial comparing conservative treatment with total mastectomy in early breast cancer patients
Arriagada, R., Lê, M. G., Guinebretière, J.-M., Dunant, A., Rochard, F., & Tursz, T. (2003) · Annals of Oncology
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 179
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Endoplasmic reticulum retention is a common defect associated with tyrosinase-negative albinism
Halaban, R., Svedine, S., Cheng, E., Smicun, Y., Aron, R., & Hebert, D. N. (2000) · Proceedings of the National Academy of Sciences
melanin and skin pigmentationCellular transport and secretion
Cited by 179
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AB ‐Bind: Antibody binding mutational database for computational affinity predictions
Sirin, S., Apgar, J. R., Bennett, E. M., & Keating, A. E. (2016) · Protein Science
Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research
Cited by 179
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Mediation of the antiapoptotic activity of Bcl-xL protein upon interaction with VDAC1 protein
Arbel, N., Ben-Hail, D., & Shoshan-Barmatz, V. (2012) · Journal of Biological Chemistry
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 179
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Chromosome Conservation in the Bovidae
Gallagher, D. S., & Womack, J. E. (1992) · Journal of Heredity
Chromosomal and Genetic VariationsEvolution and Paleontology Studies
Cited by 179
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Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease
Reardon, J. T., & Sancar, A. (2003) · Genes & Development
DNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cited by 179
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PHGDH defines a metabolic subtype in lung adenocarcinomas with poor prognosis
Zhang, B., Zheng, A., Hydbring, P., Ambroise, G., Ouchida, A. T., Goiny, M., Vakifahmetoglu-Norberg, H., & Norberg, E. (2017) · Cell Reports
Cancer, Hypoxia, and MetabolismFerroptosis and cancer prognosis
Cited by 178
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Short Telomeres Induce a DNA Damage Response in Saccharomyces cerevisiae
IJpma, A. S., & Greider, C. W. (2003) · Molecular Biology of the Cell
Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms
Cited by 178
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Metformin: A Hopeful Promise in Aging Research
Novelle, M. G., Ali, A., Diéguez, C., Bernier, M., & de Cabo, R. (2016) · Cold Spring Harbor Perspectives in Medicine
Metabolism, Diabetes, and CancerGenetics, Aging, and Longevity in Model Organisms
Cited by 178
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From Thalidomide to Rational Molecular Glue Design for Targeted Protein Degradation
Oleinikovas, V., Gainza, P., Ryckmans, T., Fasching, B., & Thomä, N. H. (2024) · Annual Review of Pharmacology and Toxicology
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 178
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RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies
Tulloch, F., Atkinson, N. J., Evans, D. J., Ryan, M. D., & Simmonds, P. (2014) · eLife
RNA and protein synthesis mechanismsEvolution and Genetic Dynamics
Cited by 178
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EPAS1 trans-activation during hypoxia requires p42/p44 MAPK
Conrad, P. W., Freeman, T. L., Beitner-Johnson, D., & Millhorn, D. E. (1999) · Journal of Biological Chemistry
Cancer, Hypoxia, and MetabolismNeuroscience of respiration and sleep
Cited by 178
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A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells
Winter-Vann, A. M., Baron, R. A., Wong, W., dela Cruz, J., York, J. D., Gooden, D. M., Bergo, M. O., Young, S. G., Toone, E. J., & Casey, P. J. (2005) · Proceedings of the National Academy of Sciences
Protein Kinase Regulation and GTPase SignalingCancer-related gene regulation
Cited by 178
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Neuronal activity‐dependent increase of net matrix metalloproteinase activity is associated with MMP‐9 neurotoxicity after kainate
Jourquin, J., Tremblay, E., Décanis, N., Charton, G., Hanessian, S., Chollet, A., Le Diguardher, T., Khrestchatisky, M., & Rivera, S. (2003) · European Journal of Neuroscience
Protease and Inhibitor MechanismsNeuroscience and Neuropharmacology Research
Cited by 178
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Non-enzymatic template-directed synthesis on RNA random copolymers
Joyce, G. F., Inoue, T., & Orgel, L. E. (1984) · Journal of Molecular Biology
DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms
Cited by 178
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Structural basis for the action of the drug trametinib at KSR-bound MEK
Khan, Z. M., Real, A. M., Marsiglia, W. M., Chow, A., Duffy, M. E., Yerabolu, J. R., Scopton, A. P., & Dar, A. C. (2020) · Nature
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 178
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Deep learning extends de novo protein modelling coverage of genomes using iteratively predicted structural constraints
Greener, J. G., Kandathil, S. M., & Jones, D. T. (2019) · Nature Communications
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 178
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The Proteasome Regulatory Particle Alters the SAGA Coactivator to Enhance Its Interactions with Transcriptional Activators
Lee, D., Ezhkova, E., Li, B., Pattenden, S. G., Tansey, W. P., & Workman, J. L. (2005) · Cell
Genomics and Chromatin DynamicsUbiquitin and proteasome pathways
Cited by 178
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Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli
Yuan, J., Doucette, C. D., Fowler, W. U., Feng, X., Piazza, M., Rabitz, H. A., Wingreen, N. S., & Rabinowitz, J. D. (2009) · Molecular Systems Biology
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 178
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Omental adipose tissue-derived stromal cells promote vascularization and growth of endometrial tumors
Klopp, A. H., Zhang, Y., Solley, T., Amaya-Manzanares, F., Marini, F., Andreeff, M., Debeb, B., Woodward, W., Schmandt, R., Broaddus, R., et al. (2012) · Clinical Cancer Research
Mesenchymal stem cell researchCancer Cells and Metastasis
Cited by 178
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