Most cited biochemistry, genetics and molecular biology papers
- Verified
Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?
Levinson, D. F., Mostafavi, S., Milaneschi, Y., Rivera, M., Ripke, S., Wray, N. R., & Sullivan, P. F. (2014) · Biological Psychiatry
Genetic Associations and EpidemiologyTreatment of Major Depression
Cited by 159
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Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization
Dai, H., Smith, A., Meng, X. W., Schneider, P. A., Pang, Y.-P., & Kaufmann, S. H. (2011) · Journal of Cell Biology
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 159
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The role of tubulin–tubulin lattice contacts in the mechanism of microtubule dynamic instability
Manka, S. W., & Moores, C. A. (2018) · Nature Structural & Molecular Biology
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 159
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Molecular mechanisms of brain aging and neurodegenerative disorders: Lessons from dietary restriction
Prolla, T. A., & Mattson, M. P. (2001) · Trends in Neurosciences
Genetics, Aging, and Longevity in Model OrganismsAntioxidants, Aging, Portulaca oleracea
Cited by 159
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CNVs in neuropsychiatric disorders
Kirov, G. (2015) · Human Molecular Genetics
Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment
Cited by 159
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Exploring deep learning for complex trait genomic prediction in polyploid outcrossing species
Zingaretti, L. M., Gezan, S. A., Ferrão, L. F. V., Osorio, L. F., Monfort, A., Muñoz, P. R., Whitaker, V. M., & Pérez-Enciso, M. (2020) · Frontiers in Plant Science
Genetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals
Cited by 159
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Axillary staging after neoadjuvant chemotherapy for breast cancer: a pilot study combining sentinel lymph node biopsy with radioactive seed localization of pre-treatment positive axillary lymph nodes
Diego, E. J., McAuliffe, P. F., Soran, A., McGuire, K. P., Johnson, R. R., Bonaventura, M., & Ahrendt, G. M. (2016) · Annals of Surgical Oncology
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 159
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Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation
Diehl, F. F., Lewis, C. A., Fiske, B. P., & Vander Heiden, M. G. (2019) · Nature Metabolism
Cancer, Hypoxia, and MetabolismBiochemical and Molecular Research
Cited by 159
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Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing
Sato, K., Oiwa, R., Kumita, W., Henry, R., Sakuma, T., Ito, R., Nozu, R., Inoue, T., Katano, I., Sato, K., et al. (2016) · Cell Stem Cell
CRISPR and Genetic EngineeringAnimal Genetics and Reproduction
Cited by 159
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How mitochondria record the effects of UV exposure and oxidative stress using human skin as a model tissue
Birch-Machin, M. A., & Swalwell, H. (2010) · Mutagenesis
Mitochondrial Function and PathologySkin Protection and Aging
Cited by 159
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Potentiation of glucocorticoid receptor transcriptional activity by sumoylation
Le Drean, Y., Mincheneau, N., Le Goff, P., & Michel, D. (2002) · Endocrinology
Estrogen and related hormone effectsUbiquitin and proteasome pathways
Cited by 159
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The evolution and population diversity of human-specific segmental duplications
Dennis, M. Y., Harshman, L., Nelson, B. J., Penn, O., Cantsilieris, S., Huddleston, J., Antonacci, F., Penewit, K., Denman, L., Raja, A., et al. (2017) · Nature Ecology & Evolution
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 159
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Hsp47 as a Collagen-Specific Molecular Chaperone
Ishida, Y., & Nagata, K. (2011) · Methods in Enzymology
Heat shock proteins researchEndoplasmic Reticulum Stress and Disease
Cited by 159
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YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer
Mi, W., Guan, H., Lyu, J., Zhao, D., Xi, Y., Jiang, S., Andrews, F. H., Wang, X., Gagea, M., Wen, H., et al. (2017) · Nature Communications
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 159
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Constructing and Deconstructing Stem Cell Models of Neurological Disease
Han, S. S. W., Williams, L. A., & Eggan, K. C. (2011) · Neuron
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 159
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NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nettles, K. W., Bruning, J. B., Gil, G., Nowak, J., Sharma, S. K., Hahm, J. B., Kulp, K., Hochberg, R. B., Zhou, H., Katzenellenbogen, J. A., et al. (2008) · Nature Chemical Biology
Estrogen and related hormone effectsReceptor Mechanisms and Signaling
Cited by 159
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Reduced oxidative power but unchanged antioxidative capacity in skeletal muscle from aged humans
Tonkonogi, M., Fernström, M., Walsh, B., Ji, L. L., Rooyackers, O., Hammarqvist, F., Wernerman, J., & Sahlin, K. (2003) · Pflügers Archiv - European Journal of Physiology
Mitochondrial Function and PathologyExercise and Physiological Responses
Cited by 159
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Mechanisms of BRCA1 Tumor Suppression
Silver, D. P., & Livingston, D. M. (2012) · Cancer Discovery
BRCA gene mutations in cancerCancer-related Molecular Pathways
Cited by 159
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miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity
Allen, R. M., Marquart, T. J., Albert, C. J., Suchy, F. J., Wang, D. Q. ‐., Ananthanarayanan, M., Ford, D. A., & Baldán, Á. (2012) · EMBO Molecular Medicine
Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms
Cited by 159
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Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1
Kondratov, R. V., Vykhovanets, O., Kondratova, A. A., & Antoch, M. P. (2009) · Aging
Genetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatonin
Cited by 159
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Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis.
Shao, L., Fujii, H., Colmegna, I., Oishi, H., Goronzy, J. J., & Weyand, C. M. (2009) · Journal of Experimental Medicine
DNA Repair MechanismsRheumatoid Arthritis Research and Therapies
Cited by 159
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A combined1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR-α null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome
Atherton, H. J., Bailey, N. J., Zhang, W., Taylor, J., Major, H., Shockcor, J., Clarke, K., & Griffin, J. L. (2006) · Physiological Genomics
Peroxisome Proliferator-Activated ReceptorsMetabolomics and Mass Spectrometry Studies
Cited by 159
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Aberrant Membranes and Double-Membrane Structures Accumulate in the Axons of Atg5-Null Purkinje Cells before Neuronal Death
Nishiyama, J., Miura, E., Mizushima, N., Watanabe, M., & Yuzaki, M. (2007) · Autophagy
Autophagy in Disease and TherapyGenetic Neurodegenerative Diseases
Cited by 159
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Regional distribution of nicotinic receptors during prenatal development of human brain and spinal cord
Hellström-Lindahl, E., Gorbounova, O., Seiger, Å., Mousavi, M., & Nordberg, A. (1998) · Developmental Brain Research
Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research
Cited by 159
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