Most cited biochemistry, genetics and molecular biology papers
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Advances in epigenetics link genetics to the environment and disease
Cavalli, G., & Heard, E. (2019) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 1,509
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Power and predictive accuracy of polygenic risk scores
Dudbridge, F. (2013) · PLoS Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 1,509
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Photodynamic therapy with endogenous protoporphyrin
Kennedy, J. C., Pottier, R. H., & Pross, D. C. (1990) · Journal of Photochemistry and Photobiology B: Biology
Photodynamic Therapy Research StudiesNonmelanoma Skin Cancer Studies
Cited by 1,509
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RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
Sabatini, D. M., Erdjument-Bromage, H., Lui, M., Tempst, P., & Snyder, S. H. (1994) · Cell
PI3K/AKT/mTOR signaling in cancerSignaling Pathways in Disease
Cited by 1,509
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Unravelling the effects of the environment and host genotype on the gut microbiome
Spor, A., Koren, O., & Ley, R. (2011) · Nature Reviews Microbiology
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 1,509
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Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes
BASKERVILLE, S., & BARTEL, D. P. (2005) · RNA
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 1,508
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Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells
Ma, C., Han, M., Heinrich, B., Fu, Q., Zhang, Q., Sandhu, M., Agdashian, D., Terabe, M., Berzofsky, J. A., Fako, V., et al. (2018) · Science
Gut microbiota and healthCholangiocarcinoma and Gallbladder Cancer Studies
Cited by 1,508
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Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.
Schreck, R., Meier, B., Männel, D. N., Dröge, W., & Baeuerle, P. A. (1992) · The Journal of experimental medicine
NF-κB Signaling PathwaysImmune Response and Inflammation
Cited by 1,508
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A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure
Baron, M., Veres, A., Wolock, S. L., Faust, A. L., Gaujoux, R., Vetere, A., Ryu, J. H., Wagner, B. K., Shen-Orr, S. S., Klein, A. M., et al. (2016) · Cell Systems
Single-cell and spatial transcriptomicsPancreatic function and diabetes
Cited by 1,508
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Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy
Cartier, N., Hacein-Bey-Abina, S., Bartholomae, C. C., Veres, G., Schmidt, M., Kutschera, I., Vidaud, M., Abel, U., Dal-Cortivo, L., Caccavelli, L., et al. (2009) · Science
Virus-based gene therapy researchLysosomal Storage Disorders Research
Cited by 1,508
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Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation
Rapraeger, A. C., Krufka, A., & Olwin, B. B. (1991) · Science
Fibroblast Growth Factor ResearchProteoglycans and glycosaminoglycans research
Cited by 1,508
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CO2 CONCENTRATING MECHANISMS IN ALGAE: Mechanisms, Environmental Modulation, and Evolution
Giordano, M., Beardall, J., & Raven, J. A. (2005) · Annual Review of Plant Biology
Photosynthetic Processes and MechanismsAlgal biology and biofuel production
Cited by 1,507
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Efficient Bayesian mixed-model analysis increases association power in large cohorts
Loh, P.-R., Tucker, G., Bulik-Sullivan, B. K., Vilhjálmsson, B. J., Finucane, H. K., Salem, R. M., Chasman, D. I., Ridker, P. M., Neale, B. M., Berger, B., et al. (2015) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,507
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Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex
Zheng, N., Schulman, B. A., Song, L., Miller, J. J., Jeffrey, P. D., Wang, P., Chu, C., Koepp, D. M., Elledge, S. J., Pagano, M., et al. (2002) · Nature
Ubiquitin and proteasome pathwaysEnzyme Structure and Function
Cited by 1,507
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Gut microbiome development along the colorectal adenoma-carcinoma sequence
Feng, Q., Liang, S., Jia, H., Stadlmayr, A., Tang, L., Lan, Z., Zhang, D., Xia, H., Xu, X., Jie, Z., et al. (2015) · Nature Communications
Gut microbiota and healthClostridium difficile and Clostridium perfringens research
Cited by 1,506
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Cancer metabolism: a therapeutic perspective
Martinez-Outschoorn, U. E., Peiris-Pagés, M., Pestell, R. G., Sotgia, F., & Lisanti, M. P. (2017) · Nature Reviews Clinical Oncology
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 1,505
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In vivo three-photon microscopy of subcortical structures within an intact mouse brain
Horton, N. G., Wang, K., Kobat, D., Clark, C. G., Wise, F. W., Schaffer, C. B., & Xu, C. (2013) · Nature Photonics
Advanced Fluorescence Microscopy TechniquesOptical Imaging and Spectroscopy Techniques
Cited by 1,505
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Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion: Roles of AMP-Activated Protein Kinase and Beclin 1 in Mediating Autophagy
Matsui, Y., Takagi, H., Qu, X., Abdellatif, M., Sakoda, H., Asano, T., Levine, B., & Sadoshima, J. (2007) · Circulation Research
Autophagy in Disease and TherapyCardiac Ischemia and Reperfusion
Cited by 1,505
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Visualization of Single RNA Transcripts in Situ
Femino, A. M., Fay, F. S., Fogarty, K., & Singer, R. H. (1998) · Science
Advanced Fluorescence Microscopy TechniquesRNA Research and Splicing
Cited by 1,504
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Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21
Inagaki, T., Dutchak, P., Zhao, G., Ding, X., Gautron, L., Parameswara, V., Li, Y., Goetz, R., Mohammadi, M., Esser, V., et al. (2007) · Cell Metabolism
Fibroblast Growth Factor ResearchPeroxisome Proliferator-Activated Receptors
Cited by 1,504
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Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
Ying, Q.-L., Stavridis, M., Griffiths, D., Li, M., & Smith, A. (2003) · Nature Biotechnology
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 1,504
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Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity
Bouillet, P., Metcalf, D., Huang, D. C. S., Tarlinton, D. M., Kay, T. W. H., Köntgen, F., Adams, J. M., & Strasser, A. (1999) · Science
Cell death mechanisms and regulationT-cell and B-cell Immunology
Cited by 1,504
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Gut/brain axis and the microbiota
Mayer, E. A., Tillisch, K., & Gupta, A. (2015) · Journal of Clinical Investigation
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,503
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Distinguishing Homologous from Analogous Proteins
Fitch, W. M. (1970) · Systematic Zoology
Genomics and Phylogenetic StudiesEvolution and Paleontology Studies
Cited by 1,503
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