Most cited biochemistry, genetics and molecular biology papers
- Verified
Direct analysis of genes encoding 16S rRNA from complex communities reveals many novel molecular species within the human gut
Suau, A., Bonnet, R., Sutren, M., Godon, J.-J., Gibson, G. R., Collins, M. D., & Doré, J. (1999) · Applied and Environmental Microbiology
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 1,490
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A Switch Between Two-, Three-, and Four-stranded Coiled Coils in GCN4 Leucine Zipper Mutants
Harbury, P. B., Zhang, T., Kim, P. S., & Alber, T. (1993) · Science
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 1,490
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Femtomolar Sensitivity of Metalloregulatory Proteins Controlling Zinc Homeostasis
Outten, C. E., & O'Halloran, A. T. V. (2001) · Science
Bacterial Genetics and BiotechnologyTrace Elements in Health
Cited by 1,489
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FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells.
Zhao, J., Brault, J. J., Schild, A., Cao, P., Sandri, M., Schiaffino, S., Lecker, S. H., & Goldberg, A. L. (2007) · Cell Metabolism
Muscle Physiology and DisordersAutophagy in Disease and Therapy
Cited by 1,489
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The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues
Lindsten, T., Ross, A. J., King, A., Zong, W.-X., Rathmell, J. C., Shiels, H. A., Ulrich, E., Waymire, K. G., Mahar, P., Frauwirth, K., et al. (2000) · Molecular Cell
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 1,489
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The long-range interaction landscape of gene promoters
Sanyal, A., Lajoie, B. R., Jain, G., & Dekker, J. (2012) · Nature
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 1,489
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Serine/threonine phosphatases: mechanism through structure
Shi, Y. (2009) · Cell
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 1,488
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mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
Cunningham, J. T., Rodgers, J. T., Arlow, D. H., Vazquez, F., Mootha, V. K., & Puigserver, P. (2007) · Nature
Metabolism, Diabetes, and CancerMitochondrial Function and Pathology
Cited by 1,488
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Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement
Nolfi-Donegan, D., Braganza, A., & Shiva, S. (2020) · Redox Biology
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 1,488
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Absolute quantification by droplet digital PCR versus analog real-time PCR
Hindson, C. M., Chevillet, J. R., Briggs, H. A., Gallichotte, E. N., Ruf, I. K., Hindson, B. J., Vessella, R. L., & Tewari, M. (2013) · Nature Methods
Molecular Biology Techniques and ApplicationsInnovative Microfluidic and Catalytic Techniques Innovation
Cited by 1,488
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The Technology and Biology of Single-Cell RNA Sequencing
Kolodziejczyk, A. A., Kim, J. K., Svensson, V., Marioni, J. C., & Teichmann, S. A. (2015) · Molecular Cell
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,487
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Growth factor regulation of autophagy and cell survival in the absence of apoptosis
Lum, J. J., Bauer, D. E., Kong, M., Harris, M. H., Li, C., Lindsten, T., & Thompson, C. B. (2005) · Cell
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 1,487
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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
Pattanayak, V., Lin, S., Guilinger, J. P., Ma, E., Doudna, J. A., & Liu, D. R. (2013) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,487
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Robust decomposition of cell type mixtures in spatial transcriptomics
Cable, D. M., Murray, E., Zou, L. S., Goeva, A., Macosko, E. Z., Chen, F., & Irizarry, R. A. (2022) · Nature Biotechnology
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 1,487
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Molecular Basis for Feedback Regulation of Bile Acid Synthesis by Nuclear Receptors
Lu, T. T., Makishima, M., Repa, J. J., Schoonjans, K., Kerr, T. A., Auwerx, J., & Mangelsdorf, D. J. (2000) · Molecular Cell
Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms
Cited by 1,487
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Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
Puigserver, P., Rhee, J., Donovan, J., Walkey, C. J., Yoon, J. C., Oriente, F., Kitamura, Y., Altomonte, J., Dong, H., Accili, D., et al. (2003) · Nature
FOXO transcription factor regulationMetabolism, Diabetes, and Cancer
Cited by 1,487
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The Science and Translation of Lactate Shuttle Theory
Brooks, G. A. (2018) · Cell Metabolism
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 1,486
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Ink4a/Arf expression is a biomarker of aging
Krishnamurthy, J., Torrice, C., Ramsey, M. R., Kovalev, G. I., Al-Regaiey, K., Su, L., & Sharpless, N. E. (2004) · Journal of Clinical Investigation
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,486
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‘Improved parameters for the Martini coarse-grained protein force field’
de Jong, D. H., Singh, G., Bennett, W. F. D., Arnarez, C., Wassenaar, T. A., Schäfer, L. V., Periole, X., Tieleman, D. P., & Marrink, S. J. (2013) · Journal of Chemical Theory and Computation
Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions
Cited by 1,486
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Induced protein degradation: an emerging drug discovery paradigm
Lai, A. C., & Crews, C. M. (2017) · Nature Reviews Drug Discovery
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 1,486
- Verified
An insight into gut microbiota and its functionalities
Adak, A., & Khan, M. R. (2019) · Cellular and Molecular Life Sciences
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 1,485
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The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution
Farh, K. K.-H., Grimson, A., Jan, C., Lewis, B. P., Johnston, W. K., Lim, L. P., Burge, C. B., & Bartel, D. P. (2005) · Science
MicroRNA in disease regulationRNA Research and Splicing
Cited by 1,484
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In vivo amplification of the androgen receptor gene and progression of human prostate cancer
Visakorpi, T., Hyytinen, E., Koivisto, P., Tanner, M., Keinänen, R., Palmberg, C., Palotie, A., Tammela, T., Isola, J., & Kallioniemi, O.-P. (1995) · Nature Genetics
Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer
Cited by 1,484
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Bias in template-to-product ratios in multitemplate PCR
Polz, M. F., & Cavanaugh, C. M. (1998) · Applied and Environmental Microbiology
Molecular Biology Techniques and ApplicationsMicrobial Community Ecology and Physiology
Cited by 1,484
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