Most cited biochemistry, genetics and molecular biology papers
- Verified
Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus
Whitesell, L., Robbins, N., Huang, D. S., McLellan, C. A., Shekhar-Guturja, T., LeBlanc, E. V., Nation, C. S., Hui, R., Hutchinson, A., Collins, C., et al. (2019) · Nature Communications
Heat shock proteins researchAntifungal resistance and susceptibility
Cited by 124
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Simvastatin suppresses breast cancer cell proliferation induced by senescent cells
Liu, S., Uppal, H., Demaria, M., Desprez, P.-Y., Campisi, J., & Kapahi, P. (2015) · Scientific Reports
Telomeres, Telomerase, and SenescenceCancer, Lipids, and Metabolism
Cited by 124
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Role of the androgen receptor in human breast cancer.
Birrell, S. N., Hall, R. E., & Tilley, W. D. (1998) · Journal of Mammary Gland Biology and Neoplasia
Estrogen and related hormone effectsBreast Cancer Treatment Studies
Cited by 124
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Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis
Heimburg, T., Chakrabarti, A., Lancelot, J., Marek, M., Melesina, J., Hauser, A.-T., Shaik, T. B., Duclaud, S., Robaa, D., Erdmann, F., et al. (2016) · Journal of Medicinal Chemistry
Histone Deacetylase Inhibitors ResearchParasites and Host Interactions
Cited by 124
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The Potential of Lonidamine in Combination with Chemotherapy and Physical Therapy in Cancer Treatment
Huang, Y., Sun, G., Sun, X., Li, F., Zhao, L., Zhong, R., & Peng, Y. (2020) · Cancers
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 124
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Activation of the Nrf2 Cell Defense Pathway by Ancient Foods: Disease Prevention by Important Molecules and Microbes Lost from the Modern Western Diet
Senger, D. R., Li, D., Jaminet, S.-C., & Cao, S. (2016) · PLOS ONE
Genomics, phytochemicals, and oxidative stressPhytochemicals and Antioxidant Activities
Cited by 124
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Cell-Selective Adeno-Associated Virus-Mediated SCN1A Gene Regulation Therapy Rescues Mortality and Seizure Phenotypes in a Dravet Syndrome Mouse Model and Is Well Tolerated in Nonhuman Primates
Tanenhaus, A., Stowe, T., Young, A., McLaughlin, J., Aeran, R., Lin, I. W., Li, J., Hosur, R., Chen, M., Leedy, J., et al. (2022) · Human Gene Therapy
Virus-based gene therapy researchEpilepsy research and treatment
Cited by 124
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Protein destabilization by electrostatic repulsions in the two‐stranded α‐helical coiled‐coil/leucine zipper
Kohn, W. D., Kay, C. M., & Hodges, R. S. (1995) · Protein Science
Protein Structure and DynamicsChemical Synthesis and Analysis
Cited by 124
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Gating, modulation and subunit composition of voltage‐gated K+ channels in dendritic inhibitory interneurones of rat hippocampus
Lien, C., Martina, M., Schultz, J. H., Ehmke, H., & Jonas, P. (2002) · The Journal of Physiology
Ion channel regulation and functionNeuroscience and Neuropharmacology Research
Cited by 124
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Impact of the solvent capacity constraint on E. coli metabolism
Vazquez, A., Beg, Q. K., deMenezes, M. A., Ernst, J., Bar-Joseph, Z., Barabási, A.-L., Boros, L. G., & Oltvai, Z. N. (2008) · BMC Systems Biology
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 124
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The Bacterium Akkermansia muciniphila: A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation
Ouyang, J., Lin, J., Isnard, S., Fombuena, B., Peng, X., Marette, A., Routy, B., Messaoudene, M., Chen, Y., & Routy, J.-P. (2020) · Frontiers in Immunology
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 124
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Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control
Yang, J.-Y., Deng, X.-Y., Li, Y.-S., Ma, X.-C., Feng, J.-X., Yu, B., Chen, Y., Luo, Y.-L., Wang, X., Chen, M.-L., et al. (2018) · Nature Communications
RNA and protein synthesis mechanismsRNA Research and Splicing
Cited by 124
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Expression Specificity of GFAP Transgenes
Su, M., Hu, H., Lee, Y., D’Azzo, A., Messing, A., & Brenner, M. (2004) · Neurochemical Research
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 124
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Structure and promoter activity of the gene for the erythroid transcription factor GATA-1.
Hannon, R., Evans, T., Felsenfeld, G., & Gould, H. (1991) · Proceedings of the National Academy of Sciences
Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders
Cited by 124
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The Otx family
Simeone, A., Puelles, E., & Acampora, D. (2002) · Current Opinion in Genetics & Development
Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms
Cited by 124
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Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity
Williamson, I., Lettice, L. A., Hill, R. E., & Bickmore, W. A. (2016) · Development
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 124
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The interaction between gut microbiota and age-related changes in immune function and inflammation
Magrone, T., & Jirillo, E. (2013) · Immunity & Ageing
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 124
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Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle
Chen, C. C. W., Erlich, A. T., & Hood, D. A. (2018) · Skeletal Muscle
Autophagy in Disease and TherapyMuscle Physiology and Disorders
Cited by 124
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mTOR Inhibition Specifically Sensitizes Colorectal Cancers with KRAS or BRAF Mutations to BCL-2/BCL-XL Inhibition by Suppressing MCL-1
Faber, A. C., Coffee, E. M., Costa, C., Dastur, A., Ebi, H., Hata, A. N., Yeo, A. T., Edelman, E. J., Song, Y., Tam, A. T., et al. (2014) · Cancer Discovery
Cell death mechanisms and regulationPI3K/AKT/mTOR signaling in cancer
Cited by 124
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1H NMR-Based Metabonomic Investigation of the Effect of Two Different Exercise Sessions on the Metabolic Fingerprint of Human Urine
Pechlivanis, A., Kostidis, S., Saraslanidis, P., Petridou, A., Tsalis, G., Mougios, V., Gika, H. G., Mikros, E., & Theodoridis, G. A. (2010) · Journal of Proteome Research
Metabolomics and Mass Spectrometry StudiesExercise and Physiological Responses
Cited by 124
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Recruitment of the Cell Cycle Checkpoint Kinase ATR to Chromatin during S-phase
Dart, D. A., Adams, K. E., Akerman, I., & Lakin, N. D. (2004) · Journal of Biological Chemistry
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 124
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Combination Therapy with the Advanced Glycation End Product Cross-Link Breaker, Alagebrium, and Angiotensin Converting Enzyme Inhibitors in Diabetes: Synergy or Redundancy?
Coughlan, M. T., Thallas-Bonke, V., Pete, J., Long, D. M., Gasser, A., Tong, D. C. K., Arnstein, M., Thorpe, S. R., Cooper, M. E., & Forbes, J. M. (2007) · Endocrinology
Advanced Glycation End Products researchChronic Kidney Disease and Diabetes
Cited by 124
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Alveolar rhabdomyosarcoma–associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression
Crose, L. E. S., Galindo, K. A., Kephart, J. G., Chen, C., Fitamant, J., Bardeesy, N., Bentley, R. C., Galindo, R. L., Ashley Chi, J.-T., & Linardic, C. M. (2014) · Journal of Clinical Investigation
Hippo pathway signaling and YAP/TAZSarcoma Diagnosis and Treatment
Cited by 124
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Correlated mutations in models of protein sequences: phylogenetic and structural effects
Lapedes, A. S., Giraud, B., Liu, L., & Stormo, G. D. (1999) · Institute of Mathematical Statistics Lecture Notes - Monograph Series
Genomics and Phylogenetic StudiesProtein Structure and Dynamics
Cited by 124
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