Most cited biochemistry, genetics and molecular biology papers
- Verified
mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy
Bordi, M., Darji, S., Sato, Y., Mellén, M., Berg, M. J., Kumar, A., Jiang, Y., & Nixon, R. A. (2019) · Cell Death & Disease
Autophagy in Disease and TherapyDown syndrome and intellectual disability research
Cited by 124
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Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues
Huby, T., Doucet, C., Dachet, C., Ouzilleau, B., Ueda, Y., Afzal, V., Rubin, E., Chapman, M. J., & Lesnik, P. (2006) · Journal of Clinical Investigation
Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases
Cited by 124
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Cell-specific production, secretion, and function of apolipoprotein E
Kockx, M., Traini, M., & Kritharides, L. (2018) · Journal of Molecular Medicine
Cholesterol and Lipid MetabolismLipid metabolism and disorders
Cited by 124
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DNA Double-Strand Break Formation upon UV-Induced Replication Stress Activates ATM and DNA-PKcs Kinases
Yajima, H., Lee, K.-J., Zhang, S., Kobayashi, J., & Chen, B. P. C. (2009) · Journal of Molecular Biology
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 124
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GTP-State-Selective Cyclic Peptide Ligands of K-Ras(G12D) Block Its Interaction with Raf
Zhang, Z., Gao, R., Hu, Q., Peacock, H., Peacock, D. M., Dai, S., Shokat, K. M., & Suga, H. (2020) · ACS Central Science
Protein Kinase Regulation and GTPase SignalingChemical Synthesis and Analysis
Cited by 124
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A Complex of Pdi1p and the Mannosidase Htm1p Initiates Clearance of Unfolded Glycoproteins from the Endoplasmic Reticulum
Gauss, R., Kanehara, K., Carvalho, P., Ng, D. T. W., & Aebi, M. (2011) · Molecular Cell
Endoplasmic Reticulum Stress and DiseaseGlycosylation and Glycoproteins Research
Cited by 124
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Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage
Walmacq, C., Cheung, A. C. M., Kireeva, M. L., Lubkowska, L., Ye, C., Gotte, D., Strathern, J. N., Carell, T., Cramer, P., & Kashlev, M. (2012) · Molecular Cell
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 124
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Senolytics for Cancer Therapy: Is All that Glitters Really Gold?
Carpenter, V. J., Saleh, T., & Gewirtz, D. A. (2021) · Cancers
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 124
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Beginning at the ends: telomeres and human disease
Savage, S. A. (2018) · F1000Research
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 124
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Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis
Zhang, D., Mott, J. L., Chang, S.-W., Denniger, G., Feng, Z., & Zassenhaus, H. P. (2000) · Genomics
Mitochondrial Function and PathologyDNA Repair Mechanisms
Cited by 124
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Oxidized proteins: Mechanisms of removal and consequences of accumulation
Dunlop, R. A., Brunk, U. T., & Rodgers, K. J. (2009) · IUBMB Life
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 124
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Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification
Şentürk, M., Lin, G., Zuo, Z., Mao, D., Watson, E., Mikos, A. G., & Bellen, H. J. (2019) · Nature Cell Biology
Autophagy in Disease and TherapyAmyotrophic Lateral Sclerosis Research
Cited by 124
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Graded expression of zinc-responsive genes through two regulatory zinc-binding sites in Zur
Shin, J.-H., Jung, H. J., An, Y. J., Cho, Y.-B., Cha, S.-S., & Roe, J.-H. (2011) · Proceedings of the National Academy of Sciences
Bacterial Genetics and BiotechnologyTrace Elements in Health
Cited by 124
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Allosteric SHP2 inhibitors in cancer: Targeting the intersection of RAS, resistance, and the immune microenvironment
Kerr, D. L., Haderk, F., & Bivona, T. G. (2021) · Current Opinion in Chemical Biology
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 124
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Natural history of rhizomelic chondrodysplasia punctata
White, A. L., Modaff, P., Holland‐Morris, F., & Pauli, R. M. (2003) · American Journal of Medical Genetics Part A
Connective tissue disorders researchCongenital limb and hand anomalies
Cited by 124
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Vildagliptin increases butyrate-producing bacteria in the gut of diabetic rats
Zhang, Q., Xiao, X., Li, M., Yu, M., Ping, F., Zheng, J., Wang, T., & Wang, X. (2017) · PLOS ONE
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 124
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Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects
Ciaraldi, T. P., Abrams, L., Nikoulina, S., Mudaliar, S., & Henry, R. R. (1995) · Journal of Clinical Investigation
Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 124
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Multiplexed Detection of MicroRNA Biomarkers Using SERS-Based Inverse Molecular Sentinel (iMS) Nanoprobes
Wang, H.-N., Crawford, B. M., Fales, A. M., Bowie, M. L., Seewaldt, V. L., & Vo-Dinh, T. (2016) · The Journal of Physical Chemistry C
Advanced biosensing and bioanalysis techniquesGold and Silver Nanoparticles Synthesis and Applications
Cited by 124
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Nitrogen Fixing Cyanobacteria: Future Prospect
A., A., Hemida, M., & Ohyam, T. (2014) · Advances in Biology and Ecology of Nitrogen Fixation
Metalloenzymes and iron-sulfur proteinsAquatic Ecosystems and Phytoplankton Dynamics
Cited by 124
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Spontaneous autoimmune diabetes mellitus in the BB rat
Like, A. A., Butler, L., Williams, R. M., Appel, M. C., Weringer, E. J., & Rossini, A. A. (1982) · Diabetes
Diabetes and associated disordersT-cell and B-cell Immunology
Cited by 124
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Approximate Bayesian computation with deep learning supports a third archaic introgression in Asia and Oceania
Mondal, M., Bertranpetit, J., & Lao, O. (2019) · Nature Communications
Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology
Cited by 124
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Automated synapse-level reconstruction of neural circuits in the larval zebrafish brain
Svara, F., Förster, D., Kubo, F., Januszewski, M., dal Maschio, M., Schubert, P. J., Kornfeld, J., Wanner, A. A., Laurell, E., Denk, W., et al. (2022) · Nature Methods
Advanced Electron Microscopy Techniques and ApplicationsCell Image Analysis Techniques
Cited by 124
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The mutational impact of culturing human pluripotent and adult stem cells
Kuijk, E., Jager, M., van der Roest, B., Locati, M. D., Van Hoeck, A., Korzelius, J., Janssen, R., Besselink, N., Boymans, S., van Boxtel, R., et al. (2020) · Nature Communications
Pluripotent Stem Cells ResearchCancer Genomics and Diagnostics
Cited by 124
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Differential Role of Actin, Clathrin, and Dynamin in Fcγ Receptor-mediated Endocytosis and Phagocytosis
Tse, S. M. L., Furuya, W., Gold, E., Schreiber, A. D., Sandvig, K., Inman, R. D., & Grinstein, S. (2003) · Journal of Biological Chemistry
Cellular transport and secretionPhagocytosis and Immune Regulation
Cited by 124
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