Most cited biochemistry, genetics and molecular biology papers
- Verified
An LTR Retrotransposon-Derived Long Noncoding RNA lncMER52A Promotes Hepatocellular Carcinoma Progression by Binding p120-Catenin
Wu, Y., Zhao, Y., Huan, L., Zhao, J., Zhou, Y., Xu, L., Hu, Z., Liu, Y., Chen, Z., Wang, L., et al. (2020) · Cancer Research
Cancer-related molecular mechanisms researchChromosomal and Genetic Variations
Cited by 72
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Stimulation of sulfated glycosaminoglycan synthesis by the tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu2+
Wegrowski, Y., Maquart, F. X., & Borel, J. P. (1992) · Life Sciences
Proteoglycans and glycosaminoglycans researchWound Healing and Treatments
Cited by 72
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Targeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene
Morano, A., Angrisano, T., Russo, G., Landi, R., Pezone, A., Bartollino, S., Zuchegna, C., Babbio, F., Bonapace, I. M., Allen, B., et al. (2014) · Nucleic Acids Research
Epigenetics and DNA MethylationDNA Repair Mechanisms
Cited by 72
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Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes
Wu, Y., Sommers, J. A., Suhasini, A. N., Leonard, T., Deakyne, J. S., Mazin, A. V., Shin-ya, K., Kitao, H., & Brosh, R. M. (2010) · Blood
DNA Repair MechanismsBlood disorders and treatments
Cited by 72
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TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: implications for a replication restart-based mechanism for ATR checkpoint activation
Yan, S., & Michael, W. M. (2009) · Cell Cycle
DNA Repair MechanismsBacterial Genetics and Biotechnology
Cited by 72
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ARSyN: a method for the identification and removal of systematic noise in multifactorial time course microarray experiments
Nueda, M. J., Ferrer, A., & Conesa, A. (2012) · Biostatistics
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 72
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Novel machine learning approaches revolutionize protein knowledge
Bordin, N., Dallago, C., Heinzinger, M., Kim, S., Littmann, M., Rauer, C., Steinegger, M., Rost, B., & Orengo, C. (2023) · Trends in Biochemical Sciences
Protein Structure and DynamicsMachine Learning in Bioinformatics
Cited by 72
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Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors
Burnett, G. L., Yang, Y. C., Aggen, J. B., Pitzen, J., Gliedt, M. K., Semko, C. M., Marquez, A., Evans, J. W., Wang, G., Won, W. S., et al. (2023) · Journal of Medicinal Chemistry
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling
Cited by 72
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Hematopoietic stem cell ageing is uncoupled from p16INK4A-mediated senescence
Attema, J. L., Pronk, C. J. H., Norddahl, G. L., Nygren, J. M., & Bryder, D. (2009) · Oncogene
Telomeres, Telomerase, and SenescenceHematopoietic Stem Cell Transplantation
Cited by 72
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Marine-derived angiogenesis inhibitors for cancer therapy
Wang, Y.-Q., & Miao, Z.-H. (2013) · Marine Drugs
Angiogenesis and VEGF in CancerBioactive natural compounds
Cited by 72
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Sphingosine‐1‐phosphate promotes tumor development and liver fibrosis in mouse model of congestive hepatopathy
Kawai, H., Osawa, Y., Matsuda, M., Tsunoda, T., Yanagida, K., Hishikawa, D., Okawara, M., Sakamoto, Y., Shimagaki, T., Tsutsui, Y., et al. (2022) · Hepatology
Sphingolipid Metabolism and SignalingLiver physiology and pathology
Cited by 72
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Comparison of DNA damage responses following equimutagenic doses of UVA and UVB: a less effective cell cycle arrest with UVA may render UVA-induced pyrimidine dimers more mutagenic than UVB-induced ones
Rünger, T. M., Farahvash, B., Hatvani, Z., & Rees, A. (2012) · Photochemical & Photobiological Sciences
DNA Repair MechanismsSkin Protection and Aging
Cited by 72
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Physiological role of the GlnK signal transduction protein of Escherichia coli: survival of nitrogen starvation
Blauwkamp, T. A., & Ninfa, A. J. (2002) · Molecular Microbiology
Bacterial Genetics and BiotechnologyBiochemical and Molecular Research
Cited by 72
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The role of CIP2A in cancer: A review and update
Soofiyani, S. R., Hejazi, M. S., & Baradaran, B. (2017) · Biomedicine & Pharmacotherapy
Cancer Mechanisms and TherapyCancer-related molecular mechanisms research
Cited by 72
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A novel milk-clotting cysteine protease from Ficus johannis: Purification and characterization
Afsharnezhad, M., Shahangian, S. S., & Sariri, R. (2019) · International Journal of Biological Macromolecules
Enzyme Production and CharacterizationPineapple and bromelain studies
Cited by 72
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Preprotein mature domains contain translocase targeting signals that are essential for secretion.
Chatzi, K. E., Sardis, M. F., Tsirigotaki, A., Koukaki, M., Šoštarić, N., Konijnenberg, A., Sobott, F., Kalodimos, C. G., Karamanou, S., & Economou, A. (2017) · Journal of Cell Biology
Bacterial Genetics and BiotechnologyCellular transport and secretion
Cited by 72
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RNA Sequencing and Proteogenomics Reveal the Importance of Leaderless mRNAs in the Radiation-Tolerant Bacterium Deinococcus deserti
de Groot, A., Roche, D., Fernandez, B., Ludanyi, M., Cruveiller, S., Pignol, D., Vallenet, D., Armengaud, J., & Blanchard, L. (2014) · Genome Biology and Evolution
RNA and protein synthesis mechanismsGenomics and Phylogenetic Studies
Cited by 72
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Metal Binding Specificity of the MntABC Permease of Neisseria gonorrhoeae and Its Influence on Bacterial Growth and Interaction with Cervical Epithelial Cells
Lim, K. H. L., Jones, C. E., vanden Hoven, R. N., Edwards, J. L., Falsetta, M. L., Apicella, M. A., Jennings, M. P., & McEwan, A. G. (2008) · Infection and Immunity
Bacterial Genetics and BiotechnologyDrug Transport and Resistance Mechanisms
Cited by 72
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Sulforaphane as anticancer agent: a double-edged sword? Tricky balance between effects on tumor cells and immune cells
Liang, J., Hänsch, G. M., Hübner, K., & Samstag, Y. (2019) · Advances in Biological Regulation
Genomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents
Cited by 72
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Tertiary alphabet for the observable protein structural universe
Mackenzie, C. O., Zhou, J., & Grigoryan, G. (2016) · Proceedings of the National Academy of Sciences
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 72
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Glymphatic fluid transport controls paravascular clearance of AAV vectors from the brain
Murlidharan, G., Crowther, A., Reardon, R. A., Song, J., & Asokan, A. (2016) · JCI Insight
Virus-based gene therapy researchCerebrospinal fluid and hydrocephalus
Cited by 72
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Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP)
Tamanini, E., Buck, I. M., Chessari, G., Chiarparin, E., Day, J. E. H., Frederickson, M., Griffiths-Jones, C. M., Hearn, K., Heightman, T. D., Iqbal, A., et al. (2017) · Journal of Medicinal Chemistry
Cell death mechanisms and regulationChemical Synthesis and Analysis
Cited by 72
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Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation
Wlodarchak, N., Guo, F., Satyshur, K. A., Jiang, L., Jeffrey, P. D., Sun, T., Stanevich, V., Mumby, M. C., & Xing, Y. (2013) · Cell Research
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 72
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Fragile X mental retardation protein is required for chemically‐induced long‐term potentiation of the hippocampus in adult mice
Shang, Y., Wang, H., Mercaldo, V., Li, X., Chen, T., & Zhuo, M. (2009) · Journal of Neurochemistry
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 72
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