Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

Zakikhani, M., Dowling, R., Fantus, I. G., Sonenberg, N., & Pollak, M. (2006) · Cancer Research

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 1,048

Genetic determinants of the gut microbiome in UK twins

Goodrich, J. K., Davenport, E. R., Beaumont, M., Jackson, M. A., Knight, R., Ober, C., Spector, T. D., Bell, J. T., Clark, A. G., & Ley, R. E. (2016) · Cell Host & Microbe

Gut microbiota and healthGenetic Associations and Epidemiology

Cited by 1,048

Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells.

Udagawa, N., Takahashi, N., Akatsu, T., Tanaka, H., Sasaki, T., Nishihara, T., Koga, T., Martin, T. J., & Suda, T. (1990) · Proceedings of the National Academy of Sciences

Bone Metabolism and DiseasesOsteomyelitis and Bone Disorders Research

Cited by 1,048

Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks

Kelley, D. R., Snoek, J., & Rinn, J. L. (2016) · Genome Research

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 1,048

Vascular Endothelial Growth Factor Inhibits the Development of Dendritic Cells and Dramatically Affects the Differentiation of Multiple Hematopoietic Lineages In Vivo

Gabrilovich, D., Ishida, T., Oyama, T., Ran, S., Kravtsov, V., Nadaf, S., & Carbone, D. P. (1998) · Blood

Angiogenesis and VEGF in CancerImmunotherapy and Immune Responses

Cited by 1,048

Impacts of chilling temperatures on photosynthesis in warm-climate plants.

Allen, D. J., & Ort, D. R. (2001) · Trends in Plant Science

Photosynthetic Processes and MechanismsPlant Stress Responses and Tolerance

Cited by 1,047

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

Akhmanova, A., & Steinmetz, M. O. (2008) · Nature Reviews Molecular Cell Biology

Microtubule and mitosis dynamicsCellular Mechanics and Interactions

Cited by 1,047

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

Kotschy, A., Szlavik, Z., Murray, J., Davidson, J., Maragno, A. L., Le Toumelin-Braizat, G., Chanrion, M., Kelly, G. L., Gong, J.-N., Moujalled, D. M., et al. (2016) · Nature

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 1,047

Super-resolution microscopy with DNA-PAINT

Schnitzbauer, J., Strauss, M. T., Schlichthaerle, T., Schueder, F., & Jungmann, R. (2017) · Nature Protocols

Advanced Fluorescence Microscopy TechniquesAdvanced biosensing and bioanalysis techniques

Cited by 1,047

The role of regulatory variation in complex traits and disease

Albert, F. W., & Kruglyak, L. (2015) · Nature Reviews Genetics

Genetic Associations and EpidemiologyRNA Research and Splicing

Cited by 1,047

Detection of ultra-rare mutations by next-generation sequencing

Schmitt, M. W., Kennedy, S. R., Salk, J. J., Fox, E. J., Hiatt, J. B., & Loeb, L. A. (2012) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesGenomics and Rare Diseases

Cited by 1,047

The signals and pathways activating cellular senescence

Ben-Porath, I., & Weinberg, R. A. (2005) · The International Journal of Biochemistry & Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,046

Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits

Comery, T. A., Harris, J. B., Willems, P. J., Oostra, B. A., Irwin, S. A., Weiler, I. J., & Greenough, W. T. (1997) · Proceedings of the National Academy of Sciences

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 1,046

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

Tabebordbar, M., Zhu, K., Cheng, J. K. W., Chew, W. L., Widrick, J. J., Yan, W. X., Maesner, C., Wu, E. Y., Xiao, R., Ran, F. A., et al. (2016) · Science

CRISPR and Genetic EngineeringMuscle Physiology and Disorders

Cited by 1,046

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

Javierre, B. M., Burren, O. S., Wilder, S. P., Kreuzhuber, R., Hill, S. M., Sewitz, S., Cairns, J., Wingett, S. W., Várnai, C., Thiecke, M. J., et al. (2016) · Cell

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 1,046

High resolution of quantitative traits into multiple loci via interval mapping.

Jansen, R. C., & Stam, P. (1994) · Genetics

Genetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock

Cited by 1,046

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

Chien, Y., Scuoppo, C., Wang, X., Fang, X., Balgley, B., Bolden, J. E., Premsrirut, P., Luo, W., Chicas, A., Lee, C. S., et al. (2011) · Genes & Development

Telomeres, Telomerase, and SenescenceNF-κB Signaling Pathways

Cited by 1,046

A role for ATR in the DNA damage-induced phosphorylation of p53

Tibbetts, R. S., Brumbaugh, K. M., Williams, J. M., Sarkaria, J. N., Cliby, W. A., Shieh, S.-Y., Taya, Y., Prives, C., & Abraham, R. T. (1999) · Genes & Development

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 1,046

Cell Hashing with barcoded antibodies enables multiplexing and doublet detection for single cell genomics

Stoeckius, M., Zheng, S., Houck-Loomis, B., Hao, S., Yeung, B. Z., Mauck, W. M., Smibert, P., & Satija, R. (2018) · Genome Biology

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,046

Lamin B1 loss is a senescence-associated biomarker

Freund, A., Laberge, R.-M., Demaria, M., & Campisi, J. (2012) · Molecular Biology of the Cell

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 1,046

Hypoxic enhancement of exosome release by breast cancer cells

King, H. W., Michael, M. Z., & Gleadle, J. M. (2012) · BMC Cancer

Extracellular vesicles in diseaseCancer, Hypoxia, and Metabolism

Cited by 1,045

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer

Wang, K., Yuen, S. T., Xu, J., Lee, S. P., Yan, H. H. N., Shi, S. T., Siu, H. C., Deng, S., Chu, K. M., Law, S., et al. (2014) · Nature Genetics

Cancer Genomics and DiagnosticsGastric Cancer Management and Outcomes

Cited by 1,045

Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas

Moncada, R., Barkley, D., Wagner, F., Chiodin, M., Devlin, J. C., Baron, M., Hajdu, C. H., Simeone, D. M., & Yanai, I. (2020) · Nature Biotechnology

Single-cell and spatial transcriptomicsPancreatic and Hepatic Oncology Research

Cited by 1,045

Caspase Cleaved BID Targets Mitochondria and Is Required for Cytochrome c Release, while BCL-XL Prevents This Release but Not Tumor Necrosis Factor-R1/Fas Death

Gross, A., Yin, X.-M., Wang, K., Wei, M. C., Jockel, J., Milliman, C., Erdjument-Bromage, H., Tempst, P., & Korsmeyer, S. J. (1999) · Journal of Biological Chemistry

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 1,045