Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Mechanism by which metformin reduces glucose production in type 2 diabetes.

Hundal, R. S., Krssak, M., Dufour, S., Laurent, D., Lebon, V, Chandramouli, V, Inzucchi, S. E., Schumann, W. C., Petersen, K. F., Landau, B. R., et al. (2000) · Diabetes

Metabolism, Diabetes, and CancerDiabetes Treatment and Management

Cited by 1,052

The Biochemical Basis of an All-or-None Cell Fate Switch in Xenopus Oocytes

Ferrell, J. E., & Machleder, E. M. (1998) · Science

Gene Regulatory Network AnalysisDevelopmental Biology and Gene Regulation

Cited by 1,052

Gut microbiota and cardiovascular disease.

Witkowski, M., Weeks, T. L., & Hazen, S. L. (2020) · Circulation Research

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 1,051

An improved zinc-finger nuclease architecture for highly specific genome editing

Miller, J. C., Holmes, M. C., Wang, J., Guschin, D. Y., Lee, Y.-L., Rupniewski, I., Beausejour, C. M., Waite, A. J., Wang, N. S., Kim, K. A., et al. (2007) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,051

NF-κB in oxidative stress

Lingappan, K. (2018) · Current Opinion in Toxicology

NF-κB Signaling PathwaysRedox biology and oxidative stress

Cited by 1,051

Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function

Bassell, G. J., & Warren, S. T. (2008) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 1,051

Best practices for single-cell analysis across modalities

Heumos, L., Schaar, A. C., Lance, C., Litinetskaya, A., Drost, F., Zappia, L., Lücken, M. D., Strobl, D. C., Henao, J., Curion, F., et al. (2023) · Nature Reviews Genetics

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 1,051

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

Zhu, S., Wu, H., Wu, F., Nie, D., Sheng, S., & Mo, Y.-Y. (2008) · Cell Research

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 1,051

DNA repair dysregulation from cancer driver to therapeutic target

Curtin, N. J. (2012) · Nature Reviews Cancer

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 1,051

The genetic architecture of type 2 diabetes

Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., et al. (2016) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,051

Role of Translocation in the Activation and Function of Protein Kinase B

Andjelkovic, M., Alessi, D. R., Meier, R., Fernandez, A., Lamb, N. J. C., Frech, M., Cron, P., Cohen, P., Lucocq, J. M., & Hemmings, B. A. (1997) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 1,051

The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters

Bar-Even, A., Noor, E., Savir, Y., Liebermeister, W., Davidi, D., Tawfik, D. S., & Milo, R. (2011) · Biochemistry

Evolution and Genetic DynamicsEnzyme Catalysis and Immobilization

Cited by 1,050

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

Peric-Hupkes, D., Meuleman, W., Pagie, L., Bruggeman, S. W. M., Solovei, I., Brugman, W., Gräf, S., Flicek, P., Kerkhoven, R. M., van Lohuizen, M., et al. (2010) · Molecular Cell

Nuclear Structure and FunctionGenomics and Chromatin Dynamics

Cited by 1,050

Defining normoxia, physoxia and hypoxia in tumours—implications for treatment response

McKeown, S. R. (2014) · The British Journal of Radiology

Cancer, Hypoxia, and MetabolismMathematical Biology Tumor Growth

Cited by 1,050

Blood Flow Regulation by S -Nitrosohemoglobin in the Physiological Oxygen Gradient

Stamler, J. S., Jia, L., Eu, J. P., McMahon, T. J., Demchenko, I. T., Bonaventura, J., Gernert, K., & Piantadosi, C. A. (1997) · Science

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 1,050

A Senescence Program Controlled by p53 and p16INK4a Contributes to the Outcome of Cancer Therapy

Schmitt, C. A., Fridman, J. S., Yang, M., Lee, S., Baranov, E., Hoffman, R. M., & Lowe, S. W. (2002) · Cell

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 1,050

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

Stegle, O., Parts, L., Piipari, M., Winn, J., & Durbin, R. (2012) · Nature Protocols

Genetic Associations and EpidemiologyGene expression and cancer classification

Cited by 1,049

Robustness of cellular functions

Stelling, J., Sauer, U., Szallasi, Z., Doyle, F. J., & Doyle, J. (2004) · Cell

Gene Regulatory Network AnalysisEvolution and Genetic Dynamics

Cited by 1,049

G-protein-coupled receptors and signaling networks: emerging paradigms

Marinissen, M. J., & Gutkind, J. S. (2001) · Trends in Pharmacological Sciences

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 1,049

Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

Li, W., Notani, D., Ma, Q., Tanasa, B., Nunez, E., Chen, A. Y., Merkurjev, D., Zhang, J., Ohgi, K., Song, X., et al. (2013) · Nature

Cancer-related molecular mechanisms researchGenomics and Chromatin Dynamics

Cited by 1,049

Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: Prospective cohort study of about 300,000 women in us seer cancer registries

Darby, S. C., McGale, P., Taylor, C. W., & Peto, R. (2005) · The Lancet Oncology

Breast Cancer Treatment StudiesEffects of Radiation Exposure

Cited by 1,049

The gut microbiota at the intersection of diet and human health

Gentile, C. L., & Weir, T. L. (2018) · Science

Gut microbiota and healthNutritional Studies and Diet

Cited by 1,049

mRNA localization: Gene expression in the spatial dimension

Martin, K. C., & Ephrussi, A. (2009) · Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 1,048

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

Stecher, B., Robbiani, R., Walker, A. W., Westendorf, A. M., Barthel, M., Kremer, M., Chaffron, S., Macpherson, A. J., Buer, J., Parkhill, J., et al. (2007) · PLoS Biology

Gut microbiota and healthSalmonella and Campylobacter epidemiology

Cited by 1,048