Most cited biochemistry, genetics and molecular biology papers
- Verified
Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs
Jabłońska-Trypuć, A., Matejczyk, M., & Rosochacki, S. (2016) · Journal of Enzyme Inhibition and Medicinal Chemistry
Protease and Inhibitor MechanismsPeptidase Inhibition and Analysis
Cited by 1,042
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Computational methods for transcriptome annotation and quantification using RNA-seq
Garber, M., Grabherr, M. G., Guttman, M., & Trapnell, C. (2011) · Nature Methods
Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics
Cited by 1,042
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The Osteocyte: An Endocrine Cell … and More
Dallas, S. L., Prideaux, M., & Bonewald, L. F. (2013) · Endocrine Reviews
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 1,042
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A-to-I editing of coding and non-coding RNAs by ADARs
Nishikura, K. (2016) · Nature Reviews Molecular Cell Biology
RNA regulation and diseaseRNA Research and Splicing
Cited by 1,041
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Glutathione in Cancer Biology and Therapy
Estrela, J. M., Ortega, A., & Obrador, E. (2006) · Critical Reviews in Clinical Laboratory Sciences
Sulfur Compounds in BiologyGlutathione Transferases and Polymorphisms
Cited by 1,041
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Generation of human induced pluripotent stem cells from dermal fibroblasts
Lowry, W. E., Richter, L., Yachechko, R., Pyle, A. D., Tchieu, J., Sridharan, R., Clark, A. T., & Plath, K. (2008) · Proceedings of the National Academy of Sciences
Pluripotent Stem Cells ResearchMesenchymal stem cell research
Cited by 1,041
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Oxidative protein folding in eukaryotes
Tu, B. P., & Weissman, J. S. (2004) · The Journal of Cell Biology
Redox biology and oxidative stressEndoplasmic Reticulum Stress and Disease
Cited by 1,041
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Global and Deep Molecular Analysis of Microbiota Signatures in Fecal Samples From Patients With Irritable Bowel Syndrome
Rajilić–Stojanović, M., Biagi, E., Heilig, H. G. H. J., Kajander, K., Kekkonen, R. A., Tims, S., & de Vos, W. M. (2011) · Gastroenterology
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,041
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Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study
Rauch, A., Wieczorek, D., Graf, E., Wieland, T., Endele, S., Schwarzmayr, T., Albrecht, B., Bartholdi, D., Beygo, J., Di Donato, N., et al. (2012) · The Lancet
Genomics and Rare DiseasesGenetics and Neurodevelopmental Disorders
Cited by 1,041
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The UK10K project identifies rare variants in health and disease
The UK10K Consortium, Writing group, Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R. B., Xu, C., et al. (2015) · Nature
Genetic Associations and EpidemiologyGenomics and Rare Diseases
Cited by 1,040
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Microbial Biosynthesis of Alkanes
Schirmer, A., Rude, M. A., Li, X., Popova, E., & del Cardayre, S. B. (2010) · Science
Microbial Metabolic Engineering and BioproductionMicrobial bioremediation and biosurfactants
Cited by 1,040
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Role of TET enzymes in DNA methylation, development, and cancer
Rasmussen, K. D., & Helin, K. (2016) · Genes & Development
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 1,040
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New evidences on the altered gut microbiota in autism spectrum disorders
Strati, F., Cavalieri, D., Albanese, D., De Felice, C., Donati, C., Hayek, J., Jousson, O., Leoncini, S., Renzi, D., Calabrò, A., et al. (2017) · Microbiome
Gut microbiota and healthAutism Spectrum Disorder Research
Cited by 1,040
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Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo
Meng, T.-C., Fukada, T., & Tonks, N. K. (2002) · Molecular Cell
Protein Tyrosine PhosphatasesRedox biology and oxidative stress
Cited by 1,040
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A microRNA array reveals extensive regulation of microRNAs during brain development
KRICHEVSKY, A. M., KING, K. S., DONAHUE, C. P., KHRAPKO, K., & KOSIK, K. S. (2003) · RNA
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 1,040
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Guanylate cyclase and the ⋅NO/cGMP signaling pathway
Denninger, J. W., & Marletta, M. A. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Hemoglobin structure and functionNitric Oxide and Endothelin Effects
Cited by 1,040
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Is a new and general theory of molecular systematics emerging?
Edwards, S. V. (2009) · Evolution
Genomics and Phylogenetic StudiesGenetic diversity and population structure
Cited by 1,040
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p38MAPK is a novel DNA damage response‐independent regulator of the senescence‐associated secretory phenotype
Freund, A., Patil, C. K., & Campisi, J. (2011) · The EMBO Journal
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,039
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Gene expression regulation by retinoic acid
Balmer, J. E., & Blomhoff, R. (2002) · Journal of Lipid Research
Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors
Cited by 1,039
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Advances in therapeutic applications of extracellular vesicles
Wiklander, O. P. B., Brennan, M. Á., Lötvall, J., Breakefield, X. O., & EL Andaloussi, S. (2019) · Science Translational Medicine
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 1,039
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Sphingosine-1-phosphate signaling and its role in disease
Maceyka, M., Harikumar, K. B., Milstien, S., & Spiegel, S. (2012) · Trends in Cell Biology
Sphingolipid Metabolism and SignalingLysosomal Storage Disorders Research
Cited by 1,039
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Autophagy and apoptosis dysfunction in neurodegenerative disorders
Ghavami, S., Shojaei, S., Yeganeh, B., Ande, S. R., Jangamreddy, J. R., Mehrpour, M., Christoffersson, J., Chaabane, W., Moghadam, A. R., Kashani, H. H., et al. (2014) · Progress in Neurobiology
Autophagy in Disease and TherapyAlzheimer's disease research and treatments
Cited by 1,039
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Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits
Hill, W. G., Goddard, M. E., & Visscher, P. M. (2008) · PLoS Genetics
Evolution and Genetic DynamicsGenetic and phenotypic traits in livestock
Cited by 1,039
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Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation
Rajamäki, K., Lappalainen, J., Öörni, K., Välimäki, E., Matikainen, S., Kovanen, P. T., & Eklund, K. K. (2010) · PLoS ONE
Inflammasome and immune disordersAtherosclerosis and Cardiovascular Diseases
Cited by 1,039
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