Most cited biochemistry, genetics and molecular biology papers
- Verified
Caspases and their substrates
Julien, O., & Wells, J. A. (2017) · Cell Death & Differentiation
Cell death mechanisms and regulationInflammasome and immune disorders
Cited by 816
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Mesenchymal Stem/Stromal Cells (MSCs): Role as Guardians of Inflammation
Prockop, D. J., & Youn Oh, J. (2012) · Molecular Therapy
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 816
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Why highly expressed proteins evolve slowly
Drummond, D. A., Bloom, J. D., Adami, C., Wilke, C. O., & Arnold, F. H. (2005) · Proceedings of the National Academy of Sciences
Evolution and Genetic DynamicsRNA and protein synthesis mechanisms
Cited by 815
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The Molecular Diversity of Adaptive Convergence
Tenaillon, O., Rodríguez-Verdugo, A., Gaut, R. L., McDonald, P., Bennett, A. F., Long, A. D., & Gaut, B. S. (2012) · Science
Evolution and Genetic DynamicsPhilosophy of Biology and Scientific Explanation
Cited by 815
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Opening the Iron Box: Transcriptional Metalloregulation by the Fur Protein
Escolar, L., Pérez-Martín, J., & de Lorenzo, V. (1999) · Journal of Bacteriology
Bacterial Genetics and BiotechnologyIron Metabolism and Disorders
Cited by 815
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miR-155 gene: A typical multifunctional microRNA
Faraoni, I., Antonetti, F. R., Cardone, J., & Bonmassar, E. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 815
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Molecular biology of 5-HT receptors
Hannon, J., & Hoyer, D. (2008) · Behavioural Brain Research
Receptor Mechanisms and SignalingNeurotransmitter Receptor Influence on Behavior
Cited by 815
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PoPoolation2: Identifying differentiation between populations using sequencing of pooled DNA samples (Pool-Seq)
Kofler, R., Pandey, R. V., & Schlötterer, C. (2011) · Bioinformatics
Genetic diversity and population structureGenomics and Phylogenetic Studies
Cited by 815
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Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies
Horvath, S., Oshima, J., Martin, G. M., Lu, A. T., Quach, A., Cohen, H., Felton, S., Matsuyama, M., Lowe, D., Kabacik, S., et al. (2018) · Aging
Telomeres, Telomerase, and SenescenceEpigenetics and DNA Methylation
Cited by 815
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Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome
Davoli, T., Xu, A. W., Mengwasser, K. E., Sack, L. M., Yoon, J. C., Park, P. J., & Elledge, S. J. (2013) · Cell
Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities
Cited by 815
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Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
Lucas, S., Omata, Y., Hofmann, J., Böttcher, M., Iljazovic, A., Sarter, K., Albrecht, O., Schulz, O., Krishnacoumar, B., Krönke, G., et al. (2018) · Nature Communications
Bone Metabolism and DiseasesGut microbiota and health
Cited by 815
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FINEMAP: efficient variable selection using summary data from genome-wide association studies
Benner, C., Spencer, C. C. A., Havulinna, A. S., Salomaa, V., Ripatti, S., & Pirinen, M. (2016) · Bioinformatics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 815
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The mutual information: detecting and evaluating dependencies between variables
Steuer, R., Kurths, J., Daub, C. O., Weise, J., & Selbig, J. (2002) · Bioinformatics
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 815
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Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes
Young, A. R. J., Chan, E. Y. W., Hu, X. W., Köchl, R., Crawshaw, S. G., High, S., Hailey, D. W., Lippincott-Schwartz, J., & Tooze, S. A. (2006) · Journal of Cell Science
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 815
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Severe Toxicity in Nonhuman Primates and Piglets Following High-Dose Intravenous Administration of an Adeno-Associated Virus Vector Expressing Human SMN
Hinderer, C., Katz, N., Buza, E. L., Dyer, C., Goode, T., Bell, P., Richman, L. K., & Wilson, J. M. (2018) · Human Gene Therapy
Virus-based gene therapy researchNeurogenetic and Muscular Disorders Research
Cited by 814
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L1 retrotransposition in human neural progenitor cells
Coufal, N. G., Garcia-Perez, J. L., Peng, G. E., Yeo, G. W., Mu, Y., Lovci, M. T., Morell, M., O’Shea, K. S., Moran, J. V., & Gage, F. H. (2009) · Nature
Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities
Cited by 814
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Generation of Pluripotent Stem Cells from Neonatal Mouse Testis
Kanatsu-Shinohara, M., Inoue, K., Lee, J., Yoshimoto, M., Ogonuki, N., Miki, H., Baba, S., Kato, T., Kazuki, Y., Toyokuni, S., et al. (2004) · Cell
Pluripotent Stem Cells ResearchAnimal Genetics and Reproduction
Cited by 814
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CIRCLE-Seq: A highly sensitive in vitro screen for genome-wide CRISPR-cas9 nuclease off-targets
Tsai, S. Q., Nguyen, N. T., Malagon-Lopez, J., Topkar, V. V., Aryee, M. J., & Joung, J. K. (2017) · Nature Methods
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 814
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Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
Lopez-Girona, A., Mendy, D., Ito, T., Miller, K., Gandhi, A. K., Kang, J., Karasawa, S., Carmel, G., Jackson, P., Abbasian, M., et al. (2012) · Leukemia
Protein Degradation and InhibitorsMultiple Myeloma Research and Treatments
Cited by 814
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High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging
He, S., Bhatt, R., Brown, C., Brown, E. A., Buhr, D. L., Chantranuvatana, K., Danaher, P., Dunaway, D., Garrison, R. G., Geiss, G., et al. (2022) · Nature Biotechnology
Single-cell and spatial transcriptomicsAdvanced Fluorescence Microscopy Techniques
Cited by 814
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Assessing the Impact of Transgenerational Epigenetic Variation on Complex Traits
Johannes, F., Porcher, E., Teixeira, F. K., Saliba-Colombani, V., Simon, M., Agier, N., Bulski, A., Albuisson, J., Heredia, F., Audigier, P., et al. (2009) · PLoS Genetics
Epigenetics and DNA MethylationChromosomal and Genetic Variations
Cited by 814
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EIF2AK3, encoding translation initiation factor 2-α kinase 3, is mutated in patients with Wolcott-Rallison syndrome
Delépine, M., Nicolino, M., Barrett, T., Golamaully, M., Mark Lathrop, G., & Julier, C. (2000) · Nature Genetics
Diabetes and associated disordersGenomics and Rare Diseases
Cited by 813
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Genetic rescue to the rescue
Whiteley, A. R., Fitzpatrick, S. W., Funk, W. C., & Tallmon, D. A. (2015) · Trends in Ecology & Evolution
Genetic diversity and population structureEvolution and Genetic Dynamics
Cited by 813
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Estrogen promotes apoptosis of murine osteoclasts mediated by TGF–β
Hughes, D. E., Dai, A., Tiffee, J. C., Li, H. H., Mundy, G. R., & Boyce, B. F. (1996) · Nature Medicine
Bone Metabolism and DiseasesEstrogen and related hormone effects
Cited by 813
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