Most cited biochemistry, genetics and molecular biology papers
- Verified
Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle
Sinha, M., Jang, Y. C., Oh, J., Khong, D., Wu, E. Y., Manohar, R., Miller, C., Regalado, S. G., Loffredo, F. S., Pancoast, J. R., et al. (2014) · Science
Muscle Physiology and DisordersTelomeres, Telomerase, and Senescence
Cited by 824
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Tobacco smoking leads to extensive genome-wide changes in DNA methylation
Zeilinger, S., Kühnel, B., Klopp, N., Baurecht, H., Kleinschmidt, A., Gieger, C., Weidinger, S., Lattka, E., Adamski, J., Peters, A., et al. (2013) · PLoS ONE
Epigenetics and DNA MethylationSmoking Behavior and Cessation
Cited by 824
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Reconstructions of centriole formation and ciliogenesis in mammalian lungs
Sorokin, S. P. (1968) · Journal of Cell Science
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 824
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Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
Koh, A., Molinaro, A., Ståhlman, M., Khan, M. T., Schmidt, C., Mannerås-Holm, L., Wu, H., Carreras, A., Jeong, H., Olofsson, L. E., et al. (2018) · Cell
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 824
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Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway
Han, J. M., Jeong, S. J., Park, M. C., Kim, G., Kwon, N. H., Kim, H. K., Ha, S. H., Ryu, S. H., & Kim, S. (2012) · Cell
PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms
Cited by 824
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Reactive oxygen species in health and disease
Alfadda, A. A., & Sallam, R. M. (2012) · Journal of Biomedicine and Biotechnology
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 824
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Differentiation of diabetes by pathophysiology, natural history, and prognosis
Skyler, J. S., Bakris, G. L., Bonifacio, E., Darsow, T., Eckel, R. H., Groop, L., Groop, P.-H., Handelsman, Y., Insel, R. A., Mathieu, C., et al. (2017) · Diabetes
Diabetes and associated disordersDiabetes Management and Research
Cited by 823
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Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
Stadtfeld, M., Maherali, N., Breault, D. T., & Hochedlinger, K. (2008) · Cell stem cell
Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation
Cited by 823
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The clinical progress of mRNA vaccines and immunotherapies
Barbier, A. J., Jiang, A. Y., Zhang, P., Wooster, R., & Anderson, D. G. (2022) · Nature Biotechnology
RNA Interference and Gene DeliverySARS-CoV-2 and COVID-19 Research
Cited by 823
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Engineering Yeast Transcription Machinery for Improved Ethanol Tolerance and Production
Alper, H., Moxley, J., Nevoigt, E., Fink, G. R., & Stephanopoulos, G. (2006) · Science
Microbial Metabolic Engineering and BioproductionFungal and yeast genetics research
Cited by 823
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Nascent transcript sequencing visualizes transcription at nucleotide resolution
Churchman, L. S., & Weissman, J. S. (2011) · Nature
Genomics and Chromatin DynamicsRNA Research and Splicing
Cited by 823
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Inflammation, antibiotics, and diet as environmental stressors of the gut microbiome in pediatric Crohn's disease
Lewis, J. D., Chen, E. Z., Baldassano, R. N., Otley, A. R., Griffiths, A. M., Lee, D., Bittinger, K., Bailey, A., Friedman, E. S., Hoffmann, C., et al. (2015) · Cell Host & Microbe
Gut microbiota and healthInflammatory Bowel Disease
Cited by 823
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Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): An overview of their mechanisms of formation
Vistoli, G., De Maddis, D., Cipak, A., Zarkovic, N., Carini, M., & Aldini, G. (2013) · Free Radical Research
Advanced Glycation End Products researchPotato Plant Research
Cited by 823
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Telomeres and telomerase in cancer
Artandi, S. E., & DePinho, R. A. (2010) · Carcinogenesis
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 823
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p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin
Watanabe, N., Madaule, P., Reid, T., Ishizaki, T., Watanabe, G., Kakizuka, A., Saito, Y., Nakao, K., Jockusch, B. M., & Narumiya, S. (1997) · The EMBO Journal
Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions
Cited by 823
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Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
‡ (2012) · The Lancet
Genetic Associations and EpidemiologyAtherosclerosis and Cardiovascular Diseases
Cited by 823
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An RNA G-quadruplex in the 5′ UTR of the NRAS proto-oncogene modulates translation
Kumari, S., Bugaut, A., Huppert, J. L., & Balasubramanian, S. (2007) · Nature Chemical Biology
DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms
Cited by 822
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The Fanconi anaemia/BRCA pathway
D'Andrea, A. D., & Grompe, M. (2003) · Nature Reviews Cancer
DNA Repair MechanismsBlood disorders and treatments
Cited by 822
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The gut microbiota regulates bone mass in mice
Sjögren, K., Engdahl, C., Henning, P., Lerner, U. H., Tremaroli, V., Lagerquist, M. K., Bäckhed, F., & Ohlsson, C. (2012) · Journal of Bone and Mineral Research
Bone Metabolism and DiseasesGut microbiota and health
Cited by 822
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The Post-GWAS Era: From Association to Function
Gallagher, M. D., & Chen-Plotkin, A. S. (2018) · The American Journal of Human Genetics
Genetic Associations and EpidemiologyBioinformatics and Genomic Networks
Cited by 822
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Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
Broughton, S. J., Piper, M. D. W., Ikeya, T., Bass, T. M., Jacobson, J., Driege, Y., Martinez, P., Hafen, E., Withers, D. J., Leevers, S. J., et al. (2005) · Proceedings of the National Academy of Sciences
Genetics, Aging, and Longevity in Model OrganismsNeurobiology and Insect Physiology Research
Cited by 822
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Dysfunctional HDL and atherosclerotic cardiovascular disease
Rosenson, R. S., Brewer, H. B., Ansell, B. J., Barter, P., Chapman, M. J., Heinecke, J. W., Kontush, A., Tall, A. R., & Webb, N. R. (2016) · Nature Reviews Cardiology
Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases
Cited by 822
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The Advanced Glycation End Product, N∊-(Carboxymethyl)lysine, Is a Product of both Lipid Peroxidation and Glycoxidation Reactions
Fu, M.-X., Requena, J. R., Jenkins, A. J., Lyons, T. J., Baynes, J. W., & Thorpe, S. R. (1996) · Journal of Biological Chemistry
Advanced Glycation End Products researchAntioxidant Activity and Oxidative Stress
Cited by 822
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Induced fit, conformational selection and independent dynamic segments: an extended view of binding events
Csermely, P., Palotai, R., & Nussinov, R. (2010) · Trends in Biochemical Sciences
Protein Structure and DynamicsProtein Interaction Studies and Fluorescence Analysis
Cited by 821
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