Most cited biochemistry, genetics and molecular biology papers
- Verified
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
Cortellino, S., Xu, J., Sannai, M., Moore, R., Caretti, E., Cigliano, A., Le Coz, M., Devarajan, K., Wessels, A., Soprano, D., et al. (2011) · Cell
Epigenetics and DNA MethylationDNA Repair Mechanisms
Cited by 809
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Nucleus segmentation across imaging experiments: the 2018 Data Science Bowl
Caicedo, J. C., Goodman, A., Karhohs, K. W., Cimini, B. A., Ackerman, J., Haghighi, M., Heng, C., Becker, T., Doan, M., McQuin, C., et al. (2019) · Nature Methods
Cell Image Analysis TechniquesDigital Imaging for Blood Diseases
Cited by 809
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Circulating Exosomal microRNAs as Biomarkers of Colon Cancer
Ogata-Kawata, H., Izumiya, M., Kurioka, D., Honma, Y., Yamada, Y., Furuta, K., Gunji, T., Ohta, H., Okamoto, H., Sonoda, H., et al. (2014) · PLoS ONE
Extracellular vesicles in diseaseMicroRNA in disease regulation
Cited by 809
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A nutrient sensor mechanism controls Drosophila growth
Colombani, J., Raisin, S., Pantalacci, S., Radimerski, T., Montagne, J., & Léopold, P. (2003) · Cell
PI3K/AKT/mTOR signaling in cancerGenetics, Aging, and Longevity in Model Organisms
Cited by 809
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Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus
Vafiadis, P., Bennett, S. T., Todd, J. A., Nadeau, J., Grabs, R., Goodyer, C. G., Wickramasinghe, S., Colle, E., & Polychronakos, C. (1997) · Nature Genetics
Diabetes and associated disordersT-cell and B-cell Immunology
Cited by 809
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Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters
Miyake, S., Kim, S., Suda, W., Oshima, K., Nakamura, M., Matsuoka, T., Chihara, N., Tomita, A., Sato, W., Kim, S.-W., et al. (2015) · PLoS ONE
Gut microbiota and healthMultiple Sclerosis Research Studies
Cited by 809
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Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription
Zhang, Y., Feng, X.-H., & Derynck, R. (1998) · Nature
TGF-β signaling in diseasesSignaling Pathways in Disease
Cited by 809
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LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation
Solovei, I., Wang, A. S., Thanisch, K., Schmidt, C. S., Krebs, S., Zwerger, M., Cohen, T. V., Devys, D., Foisner, R., Peichl, L., et al. (2013) · Cell
Nuclear Structure and FunctionGenomics and Chromatin Dynamics
Cited by 809
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Mechanisms of normal and tumor-derived angiogenesis
Papetti, M., & Herman, I. M. (2002) · American Journal of Physiology-Cell Physiology
Angiogenesis and VEGF in CancerLymphatic System and Diseases
Cited by 809
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Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches
Sartor, R. B., & Wu, G. D. (2017) · Gastroenterology
Gut microbiota and healthInflammatory Bowel Disease
Cited by 808
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Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1
Chang, S. S., Grunder, S., Hanukoglu, A., Rösler, A., Mathew, P. M., Hanukoglu, I., Schild, L., Lu, Y., Shimkets, R. A., Nelson-Williams, C., et al. (1996) · Nature Genetics
Ion Transport and Channel RegulationIon channel regulation and function
Cited by 808
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Principles for the Buffering of Genetic Variation
Hartman IV, J. L. (2001) · Science
Evolution and Genetic DynamicsPhilosophy of Biology and Scientific Explanation
Cited by 808
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Genetic Misdiagnoses and the Potential for Health Disparities
Manrai, A. K., Funke, B. H., Rehm, H. L., Olesen, M. S., Maron, B. A., Szolovits, P., Margulies, D. M., Loscalzo, J., & Kohane, I. S. (2016) · New England Journal of Medicine
Genomics and Rare DiseasesCardiomyopathy and Myosin Studies
Cited by 808
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Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
Citorik, R. J., Mimee, M., & Lu, T. K. (2014) · Nature Biotechnology
CRISPR and Genetic EngineeringBacteriophages and microbial interactions
Cited by 808
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Properties of the Permeability Transition Pore in Mitochondria Devoid of Cyclophilin D
Basso, E., Fante, L., Fowlkes, J., Petronilli, V., Forte, M. A., & Bernardi, P. (2005) · Journal of Biological Chemistry
Mitochondrial Function and PathologySignaling Pathways in Disease
Cited by 808
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Principles for the buffering of genetic variation
Hartman, J. L., Garvik, B., & Hartwell, L. (2001) · Science
Evolution and Genetic DynamicsPhilosophy of Biology and Scientific Explanation
Cited by 808
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Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA
Chandra, V., Huang, P., Hamuro, Y., Raghuram, S., Wang, Y., Burris, T. P., & Rastinejad, F. (2008) · Nature
Peroxisome Proliferator-Activated ReceptorsProtein Structure and Dynamics
Cited by 808
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Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity
Chang, M. T., Asthana, S., Gao, S. P., Lee, B. H., Chapman, J. S., Kandoth, C., Gao, J., Socci, N. D., Solit, D. B., Olshen, A. B., et al. (2016) · Nature Biotechnology
Cancer Genomics and DiagnosticsGenomics and Rare Diseases
Cited by 808
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Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses
Calcedo, R., Vandenberghe, L. H., Gao, G., Lin, J., & Wilson, J. M. (2009) · The Journal of Infectious Diseases
Virus-based gene therapy researchVirology and Viral Diseases
Cited by 808
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The host shapes the gut microbiota via fecal microRNA
Liu, S., da Cunha, A. P., Rezende, R. M., Cialic, R., Wei, Z., Bry, L., Comstock, L. E., Gandhi, R., & Weiner, H. L. (2016) · Cell Host & Microbe
Gut microbiota and healthMicroRNA in disease regulation
Cited by 808
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Archaea and fungi of the human gut microbiome: correlations with diet and bacterial residents
Hoffmann, C., Dollive, S., Grunberg, S., Chen, J., Li, H., Wu, G. D., Lewis, J. D., & Bushman, F. D. (2013) · PLoS ONE
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 808
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A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21
the CORGI Consortium, Tomlinson, I., Webb, E., Carvajal-Carmona, L., Broderick, P., Kemp, Z., Spain, S., Penegar, S., Chandler, I., Gorman, M., et al. (2007) · Nature Genetics
Genetic Associations and EpidemiologyGenetic factors in colorectal cancer
Cited by 808
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A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog
Ichida, J. K., Blanchard, J., Lam, K., Son, E. Y., Chung, J. E., Egli, D., Loh, K. M., Carter, A. C., Di Giorgio, F. P., Koszka, K., et al. (2009) · Cell Stem Cell
Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation
Cited by 808
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Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6
Zhang, Q., Zhao, K., Shen, Q., Han, Y., Gu, Y., Li, X., Zhao, D., Liu, Y., Wang, C., Zhang, X., et al. (2015) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 807
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