Most cited biochemistry, genetics and molecular biology papers
- Verified
Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant Stress
Lander, H. M., Tauras, J. M., Ogiste, J. S., Hori, O., Moss, R. A., & Schmidt, A. M. (1997) · Journal of Biological Chemistry
Advanced Glycation End Products researchProtein Kinase Regulation and GTPase Signaling
Cited by 813
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Beclin–phosphatidylinositol 3‐kinase complex functions at the trans‐Golgi network
Kihara, A., Kabeya, Y., Ohsumi, Y., & Yoshimori, T. (2001) · The EMBO Reports
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 813
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Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family
Eckelman, B. P., Salvesen, G. S., & Scott, F. L. (2006) · The EMBO Reports
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 813
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Membrane Electroporation and Electropermeabilization: Mechanisms and Models
Kotnik, T., Rems, L., Tarek, M., & Miklavčič, D. (2019) · Annual Review of Biophysics
Microbial Inactivation MethodsLipid Membrane Structure and Behavior
Cited by 813
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The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
Heddleston, J. M., Li, Z., McLendon, R. E., Hjelmeland, A. B., & Rich, J. N. (2009) · Cell Cycle
Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis
Cited by 813
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The Radical-Pair Mechanism of Magnetoreception
Hore, P. J., & Mouritsen, H. (2016) · Annual Review of Biophysics
Electromagnetic Fields and Biological EffectsElectron Spin Resonance Studies
Cited by 813
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Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
Shi, Y., Kirwan, P., Smith, J., Robinson, H. P. C., & Livesey, F. J. (2012) · Nature Neuroscience
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 813
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Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration
Dinan, T. G., & Cryan, J. F. (2017) · The Journal of Physiology
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 813
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AMP-Activated Protein Kinase – Development of the Energy Sensor Concept
Hardie, D. G., Hawley, S. A., & Scott, J. W. (2006) · The Journal of Physiology
Metabolism, Diabetes, and CancerBiochemical and Molecular Research
Cited by 813
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Defining cell types and states with single-cell genomics
Trapnell, C. (2015) · Genome Research
Single-cell and spatial transcriptomicsGene Regulatory Network Analysis
Cited by 813
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Strong association of de novo copy number mutations with sporadic schizophrenia
Xu, B., Roos, J. L., Levy, S., van Rensburg, E. J., Gogos, J. A., & Karayiorgou, M. (2008) · Nature Genetics
Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment
Cited by 813
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Epigenetics of colorectal cancer: biomarker and therapeutic potential
Jung, G., Hernández-Illán, E., Moreira, L., Balaguer, F., & Goel, A. (2020) · Nature Reviews Gastroenterology & Hepatology
Epigenetics and DNA MethylationGenetic factors in colorectal cancer
Cited by 813
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Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution
Zhang, G., Campbell, E. A., Minakhin, L., Richter, C., Severinov, K., & Darst, S. A. (1999) · Cell
Enzyme Structure and FunctionGenomics and Chromatin Dynamics
Cited by 813
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Evidence-based path to newborn screening for Duchenne muscular dystrophy
Mendell, J. R., Shilling, C., Leslie, N. D., Flanigan, K. M., al‐Dahhak, R., Gastier‐Foster, J., Kneile, K., Dunn, D. M., Duval, B., Aoyagi, A., et al. (2012) · Annals of Neurology
Muscle Physiology and DisordersGenomics and Rare Diseases
Cited by 813
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Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
Wong, Y. C., & Holzbaur, E. L. F. (2014) · Proceedings of the National Academy of Sciences
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 812
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Chromosome aberrations in solid tumors
Albertson, D. G., Collins, C., McCormick, F., & Gray, J. W. (2003) · Nature Genetics
Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics
Cited by 812
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The Pathways Connecting G Protein-coupled Receptors to the Nucleus through Divergent Mitogen-activated Protein Kinase Cascades
Gutkind, J. S. (1998) · Journal of Biological Chemistry
Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling
Cited by 812
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The i -AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
Anand, R., Wai, T., Baker, M. J., Kladt, N., Schauss, A. C., Rugarli, E., & Langer, T. (2014) · Journal of Cell Biology
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 812
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Metal homeostasis and resistance in bacteria
Chandrangsu, P., Rensing, C., & Helmann, J. D. (2017) · Nature Reviews Microbiology
Bacterial Genetics and BiotechnologyEscherichia coli research studies
Cited by 812
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Evidence for Two Independent Domestications of Cattle
Loftus, R. T., MacHugh, D. E., Bradley, D. G., Sharp, P. M., & Cunningham, P. (1994) · Proceedings of the National Academy of Sciences
Genetic and phenotypic traits in livestockGenetic diversity and population structure
Cited by 812
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Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases.
Zheng, J., Haberland, V., Baird, D., Walker, V., Haycock, P., Hurle, M., Gutteridge, A., Erola, P., Liu, Y., Luo, S., et al. (2019) · Nature Genetics
Genetic Associations and EpidemiologyBioinformatics and Genomic Networks
Cited by 812
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Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion
Shimatani, Z., Kashojiya, S., Takayama, M., Terada, R., Arazoe, T., Ishii, H., Teramura, H., Yamamoto, T., Komatsu, H., Miura, K., et al. (2017) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 812
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A patch-clamp study of bovine chromaffin cells and of their sensitivity to acetylcholine
Fenwick, E. M., Marty, A., & Neher, E. (1982) · The Journal of Physiology
Ion channel regulation and functionNicotinic Acetylcholine Receptors Study
Cited by 812
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Pyruvate kinase type M2 and its role in tumor growth and spreading
Mazurek, S., Boschek, C. B., Hugo, F., & Eigenbrodt, E. (2005) · Seminars in Cancer Biology
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 812
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