Most cited biochemistry, genetics and molecular biology papers
- Verified
Functions of heparan sulfate proteoglycans in cell signaling during development
Lin, X. (2004) · Development
Proteoglycans and glycosaminoglycans researchDevelopmental Biology and Gene Regulation
Cited by 678
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Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
Park, J.-H., Wacholder, S., Gail, M. H., Peters, U., Jacobs, K. B., Chanock, S. J., & Chatterjee, N. (2010) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 678
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Dietary Polyphenols Promote Growth of the Gut Bacterium Akkermansia muciniphila and Attenuate High-Fat Diet–Induced Metabolic Syndrome
Roopchand, D. E., Carmody, R. N., Kuhn, P., Moskal, K., Rojas-Silva, P., Turnbaugh, P. J., & Raskin, I. (2015) · Diabetes
Gut microbiota and healthPhytochemicals and Antioxidant Activities
Cited by 678
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The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
Kapitein, L. C., Peterman, E. J. G., Kwok, B. H., Kim, J. H., Kapoor, T. M., & Schmidt, C. F. (2005) · Nature
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 678
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Progress towards in Vivo Use of siRNAs
Behlke, M. A. (2006) · Molecular Therapy
RNA Interference and Gene DeliveryCRISPR and Genetic Engineering
Cited by 677
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Hsp90 inhibitors as novel cancer chemotherapeutic agents
Neckers, L. (2002) · Trends in Molecular Medicine
Heat shock proteins researchUbiquitin and proteasome pathways
Cited by 677
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CIP2A inhibits PP2A in human malignancies
Junttila, M. R., Puustinen, P., Niemelä, M., Ahola, R., Arnold, H., Böttzauw, T., Ala-aho, R., Nielsen, C., Ivaska, J., Taya, Y., et al. (2007) · Cell
Cancer Mechanisms and TherapyProtein Tyrosine Phosphatases
Cited by 677
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Telomerase activity in human ovarian carcinoma.
Counter, C. M., Hirte, H. W., Bacchetti, S., & Harley, C. B. (1994) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceOvarian cancer diagnosis and treatment
Cited by 677
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CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus
Splinter, E., Heath, H., Kooren, J., Palstra, R.-J., Klous, P., Grosveld, F., Galjart, N., & de Laat, W. (2006) · Genes & Development
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 677
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Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation
Coletta, C., Papapetropoulos, A., Erdelyi, K., Olah, G., Módis, K., Panopoulos, P., Asimakopoulou, A., Gerö, D., Sharina, I., Martin, E., et al. (2012) · Proceedings of the National Academy of Sciences
Sulfur Compounds in BiologyNitric Oxide and Endothelin Effects
Cited by 677
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A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy
Ruas, J. L., White, J. P., Rao, R. R., Kleiner, S., Brannan, K. T., Harrison, B. C., Greene, N. P., Wu, J., Estall, J. L., Irving, B. A., et al. (2012) · Cell
Muscle Physiology and DisordersAdipose Tissue and Metabolism
Cited by 677
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Energy metabolism in uncoupling protein 3 gene knockout mice
Vidal-Puig, A. J., Grujic, D., Zhang, C.-Y., Hagen, T., Boss, O., Ido, Y., Szczepanik, A., Wade, J., Mootha, V., Cortright, R., et al. (2000) · Journal of Biological Chemistry
Mitochondrial Function and PathologyAdipose Tissue and Metabolism
Cited by 677
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Dissecting cell identity via network inference and in silico gene perturbation
Kamimoto, K., Stringa, B., Hoffmann, C. M., Jindal, K., Solnica-Krezel, L., & Morris, S. A. (2023) · Nature
Gene Regulatory Network AnalysisSingle-cell and spatial transcriptomics
Cited by 677
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Fecal microbiota transplantation and emerging applications
Borody, T. J., & Khoruts, A. (2012) · Nature Reviews Gastroenterology & Hepatology
Gut microbiota and healthClostridium difficile and Clostridium perfringens research
Cited by 677
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Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally
Huang, H., Weng, H., Zhou, K., Wu, T., Zhao, B. S., Sun, M., Chen, Z., Deng, X., Xiao, G., Auer, F., et al. (2019) · Nature
RNA modifications and cancerEpigenetics and DNA Methylation
Cited by 677
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Antiangiogenic Agents Can Increase Lymphocyte Infiltration into Tumor and Enhance the Effectiveness of Adoptive Immunotherapy of Cancer
Shrimali, R. K., Yu, Z., Theoret, M. R., Chinnasamy, D., Restifo, N. P., & Rosenberg, S. A. (2010) · Cancer Research
Angiogenesis and VEGF in CancerCancer Immunotherapy and Biomarkers
Cited by 677
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Rejuvenation of the muscle stem cell population restores strength to injured aged muscles
Cosgrove, B. D., Gilbert, P. M., Porpiglia, E., Mourkioti, F., Lee, S. P., Corbel, S. Y., Llewellyn, M. E., Delp, S. L., & Blau, H. M. (2014) · Nature Medicine
Muscle Physiology and DisordersMesenchymal stem cell research
Cited by 677
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Histone acetylation and deacetylation in yeast
Kurdistani, S. K., & Grunstein, M. (2003) · Nature Reviews Molecular Cell Biology
Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research
Cited by 677
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The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris
Martina, J. A., Diab, H. I., Lishu, L., Jeong-A, L., Patange, S., Raben, N., & Puertollano, R. (2014) · Science Signaling
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 677
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Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.
Morris, E. J., Jha, S., Restaino, C. R., Dayananth, P., Zhu, H., Cooper, A., Carr, D., Deng, Y., Jin, W., Black, S., et al. (2013) · Cancer Discovery
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 676
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Multiple roles of HDAC inhibition in neurodegenerative conditions
Chuang, D.-M., Leng, Y., Marinova, Z., Kim, H.-J., & Chiu, C.-T. (2009) · Trends in Neurosciences
Histone Deacetylase Inhibitors ResearchAlzheimer's disease research and treatments
Cited by 676
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Neural KCNQ (Kv7) channels
Brown, D. A., & Passmore, G. M. (2009) · British Journal of Pharmacology
Ion channel regulation and functionNeuroscience and Neuropharmacology Research
Cited by 676
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Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome
Shin, Y., Chang, Y.-C., Lee, D. S. W., Berry, J., Sanders, D. W., Ronceray, P., Wingreen, N. S., Haataja, M., & Brangwynne, C. P. (2018) · Cell
Genomics and Chromatin DynamicsRNA Research and Splicing
Cited by 676
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BRAKER3: Fully automated genome annotation using RNA-seq and protein evidence with GeneMark-ETP, AUGUSTUS, and TSEBRA
Gabriel, L., Brůna, T., Hoff, K. J., Ebel, M., Lomsadze, A., Borodovsky, M., & Stanke, M. (2024) · Genome Research
Genomics and Phylogenetic StudiesChromosomal and Genetic Variations
Cited by 676
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