Most cited biochemistry, genetics and molecular biology papers
- Verified
Molecular and Physiological Diversity of Nicotinic Acetylcholine Receptors in the Midbrain Dopaminergic Nuclei
Klink, R., d'Exaerde, A. D. K., Zoli, M., & Changeux, J.-P. (2001) · The Journal of Neuroscience
Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research
Cited by 674
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Targeting the cancer kinome through polypharmacology
Knight, Z. A., Lin, H., & Shokat, K. M. (2010) · Nature reviews. Cancer
Cancer Mechanisms and TherapyProtein Kinase Regulation and GTPase Signaling
Cited by 674
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Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
Perkins, N. D. (2006) · Oncogene
NF-κB Signaling PathwaysSignaling Pathways in Disease
Cited by 674
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A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism
Samuel, B. S., & Gordon, J. I. (2006) · Proceedings of the National Academy of Sciences
Gut microbiota and healthAnaerobic Digestion and Biogas Production
Cited by 674
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Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery
Angers, S., Li, T., Yi, X., MacCoss, M. J., Moon, R. T., & Zheng, N. (2006) · Nature
Ubiquitin and proteasome pathwaysEnzyme Structure and Function
Cited by 674
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A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
The Coronary Artery Disease (C4D) Genetics Consortium (2011) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 674
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BACH1, a Novel Helicase-like Protein, Interacts Directly with BRCA1 and Contributes to Its DNA Repair Function
Cantor, S. B., Bell, D. W., Ganesan, S., Kass, E. M., Drapkin, R., Grossman, S., Wahrer, D. C. R., Sgroi, D. C., Lane, W. S., Haber, D. A., et al. (2001) · Cell
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 674
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Clinical assessment incorporating a personal genome
Ashley, E. A., Butte, A. J., Wheeler, M. T., Chen, R., Klein, T. E., Dewey, F. E., Dudley, J. T., Ormond, K. E., Pavlovic, A., Morgan, A. A., et al. (2010) · The Lancet
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 674
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miRNA interplay: mechanisms and consequences in cancer
Hill, M., & Tran, N. (2021) · Disease Models & Mechanisms
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 674
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Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging
Youm, Y.-H., Grant, R. W., McCabe, L. R., Albarado, D. C., Nguyen, K. Y., Ravussin, A., Pistell, P., Newman, S., Carter, R., Laque, A., et al. (2013) · Cell Metabolism
Inflammasome and immune disordersGenetics, Aging, and Longevity in Model Organisms
Cited by 674
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The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
Wu, X., Senechal, K., Neshat, M. S., Whang, Y. E., & Sawyers, C. L. (1998) · Proceedings of the National Academy of Sciences
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 674
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Nucleotide excision repair and human syndromes
de Boer, J., & Hoeijmakers, J. H. J. (2000) · Carcinogenesis
DNA Repair MechanismsGenetic and rare skin diseases.
Cited by 674
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Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway
Guo, X., Aviles, G., Liu, Y., Tian, R., Unger, B. A., Lin, Y.-H. T., Wiita, A. P., Xu, K., Correia, M. A., & Kampmann, M. (2020) · Nature
Endoplasmic Reticulum Stress and DiseaseMitochondrial Function and Pathology
Cited by 674
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Small‐Molecule PROTACS: New Approaches to Protein Degradation
Toure, M., & Crews, C. M. (2016) · Angewandte Chemie International Edition
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 674
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Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer
Jeselsohn, R., Yelensky, R., Buchwalter, G., Frampton, G., Meric-Bernstam, F., Gonzalez-Angulo, A. M., Ferrer-Lozano, J., Perez-Fidalgo, J. A., Cristofanilli, M., Gómez, H., et al. (2014) · Clinical Cancer Research
Estrogen and related hormone effectsAdvanced Breast Cancer Therapies
Cited by 674
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Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data
Meisner, J., & Albrechtsen, A. (2018) · Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 673
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Formation of new chromatin domains determines pathogenicity of genomic duplications
Franke, M., Ibrahim, D. M., Andrey, G., Schwarzer, W., Heinrich, V., Schöpflin, R., Kraft, K., Kempfer, R., Jerković, I., Chan, W.-L., et al. (2016) · Nature
Genomics and Chromatin DynamicsGenomic variations and chromosomal abnormalities
Cited by 673
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Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
Sebastián, D., Hernández-Alvarez, M. I., Segalés, J., Sorianello, E., Muñoz, J. P., Sala, D., Waget, A., Liesa, M., Paz, J. C., Gopalacharyulu, P., et al. (2012) · Proceedings of the National Academy of Sciences
Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer
Cited by 673
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SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
Rebsamen, M., Pochini, L., Stasyk, T., de Araújo, M. E. G., Galluccio, M., Kandasamy, R. K., Snijder, B., Fauster, A., Rudashevskaya, E. L., Bruckner, M., et al. (2015) · Nature
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 673
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Transcellular degradation of axonal mitochondria
Davis, C.-H. O., Kim, K.-Y., Bushong, E. A., Mills, E. A., Boassa, D., Shih, T., Kinebuchi, M., Phan, S., Zhou, Y., Bihlmeyer, N. A., et al. (2014) · Proceedings of the National Academy of Sciences
Autophagy in Disease and TherapyMitochondrial Function and Pathology
Cited by 673
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ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells
Lewis, S. C., Uchiyama, L. F., & Nunnari, J. (2016) · Science
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 673
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Novel therapeutic applications of cardiac glycosides
Prassas, I., & Diamandis, E. P. (2008) · Nature Reviews Drug Discovery
Ion Transport and Channel RegulationPhytochemistry and Bioactive Compounds
Cited by 673
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Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
Ren, D., Villeneuve, N. F., Jiang, T., Wu, T., Lau, A., Toppin, H. A., & Zhang, D. D. (2011) · Proceedings of the National Academy of Sciences
Genomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents
Cited by 673
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An initial map of insertion and deletion (INDEL) variation in the human genome
Mills, R. E., Luttig, C. T., Larkins, C. E., Beauchamp, A., Tsui, C., Pittard, W. S., & Devine, S. E. (2006) · Genome Research
Genomic variations and chromosomal abnormalitiesGenetic Associations and Epidemiology
Cited by 673
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